Condition

Borderline Personality Disorder (BPD) clinical trials and research

• 11Clinical trials
• 2New in 30 days
• 8Countries

Newest Borderline Personality Disorder (BPD) clinical trials

All recruiting trials (11)

• Left DLPFC rTMS vs iTBS for emotional dysregulation, impulsivity, and NSSI in Borderline Personality Disorder

  This trial tests whether high-frequency rTMS or intermittent theta-burst stimulation over the left DLPFC can help reduce emotional instability, impulsivity, and non-suicidal self-injury in adults with Borderline Personality Disorder.

  Recruiting Ain Shams University · Cairo, Cairo Governorate · NCT07919587

• Enhanced DBT skills group for Borderline Personality Disorder

  This study tests whether a 12-week DBT skills group helps reduce self-harm and suicidal behavior in people with borderline personality disorder better than a shorter 6-month program or usual care.

  Recruiting at 7 sites Hospital Dr Sotero del Rio · Padre Las Casas, Araucania and 6 other locations · NCT07875166

• Emotional dysregulation in adolescents with complex trauma traits

  Researchers will observe teens to see how emotional dysregulation shows up in CPTSD and how it differs from BPD and PTSD.

  Recruiting University Hospital, Strasbourg, France · Strasbourg, Grand Est · NCT07794332

• TMS plus Emotion Regulation Skills Training for Borderline Personality Disorder

  This study tests whether adding transcranial magnetic stimulation to emotion regulation skills training helps people with borderline personality disorder improve their ability to manage emotions.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT07714005

• Gender and Borderline Personality Disorder: a look at relationships and self-view

  This study tests how gender identities relate to relationship experiences and self-perception in people with borderline personality disorder.

  Recruiting University Hospital Heidelberg · Heidelberg · NCT07639957

• Ketamine with DBT for suicidality in adults with treatment-resistant depression or bipolar disorder and BPD

  This study tests whether four ketamine infusions plus Dialectical Behavioural Therapy can more quickly reduce suicidal thoughts in adults with Borderline Personality Disorder and treatment-resistant depression or bipolar disorder.

  Recruiting Phase 2 University Health Network, Toronto · Toronto, Ontario · NCT07569198

• One-Day Accelerated TMS with D-cycloserine in adults with borderline personality disorder

  This study tests whether a single day of fast-tracked TMS combined with the drug D-cycloserine can help adults with Borderline Personality Disorder who have recent suicidal thoughts.

  Recruiting Phase 1/2 Mclean Hospital · Belmont, Massachusetts · NCT07460947

• Internal Family Systems therapy for borderline personality disorder

  This pilot will try Internal Family Systems (IFS) therapy to see if it reduces symptoms in people with borderline personality disorder who can participate from Ontario.

  Recruiting Waypoint Centre for Mental Health Care · Tiny, Ontario · NCT07342907

• Physical activity to help manage borderline or avoidant personality disorder

  This project will test whether an 8-week pedometer-based walking program or supervised karate can be safe, acceptable, and helpful for adults with borderline or avoidant personality disorder who are receiving outpatient treatment.

  Recruiting at 2 sites Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital · Gentofte Municipality, Capital Region and 1 other locations · NCT07341438

• See if Borderline Personality Disorder can be viewed as a Relationship-Use Disorder

  Researchers are testing whether BPD symptoms reflect an addiction-like reliance on interpersonal relationships, compared with bipolar disorder and healthy controls.

  Recruiting University Hospital, Montpellier · Montpellier · NCT07337889

• Using STEPPS therapy for patients with Borderline Personality Disorder and their families

  This study is testing whether a combined therapy program for people with Borderline Personality Disorder and their families can help them improve more than standard treatments.

  Recruiting Universitat Jaume I · Castellon, Spain · NCT06195553

Related topics

Quick answers

How many Borderline Personality Disorder (BPD) clinical trials are recruiting right now?

11, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (2 trials), Canada (2 trials), France (2 trials), Chile (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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