Clinical trial Recruiting at 2 sites Observational Ages 18 and up

Long-term outcomes after MBT for borderline personality disorder

Official title: MBT-EVOLVE: Mentalization-Based Treatment: Exploring Variability in Outcomes, Long-term Value and Experiences: A 10+ Year Follow-up of Two Types of MBT for BPD - Quantitative and Qualitative Perspectives on Long-term Functioning

Run by De Viersprong · NCT07509216 · Data updated 2026-11-12

This long-term follow-up checks how people with borderline personality disorder who received MBT in the past are doing more than 10 years later and whether the two MBT formats differ in long-term outcomes.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment113 (estimated)
SponsorDe Viersprong
Academic / other
Locations2 sites (Amsterdam and 1 other locations)
StatusRecruiting
StartedApril 2, 2026
Main results expectedDecember 2026
Study endsJune 2027
Registry record updatedSeptember 30, 2026
Trial IDNCT07509216 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with borderline personality disorder who participated in the original MBT-DH vs MBT-IOP trial and consented to long-term follow-up.

Probably not a fit

Individuals not reachable for follow-up or who did not consent may not receive insight from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational follow-up of a prior multicenter randomized trial comparing two MBT formats for borderline personality disorder. The study aims to examine long-term functioning, health care use, and costs, more than a decade after initial MBT treatment. It assesses current symptoms, interpersonal functioning, daily living skills, identity development, and participation in society to understand sustained effects and differences between MBT-DH and MBT-IOP. The investigation may help refine MBT delivery models and inform cost-effectiveness considerations. Participants include individuals who were originally randomized to MBT-DH or MBT-IOP and agreed to be contacted for follow-up.

Why it matters

Potential benefit: If successful, the study could clarify long-term benefits of MBT and guide future treatment choices and resource allocation for people with BPD.

How similar studies have gone: Prior MBT trials showed benefits up to three years; this study is novel in exploring outcomes beyond ten years.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participation in the original randomized controlled trial of mentalization-based treatment (MBT-DH versus MBT-IOP)
* Did not decline to be contacted for future research
* Able to provide informed consent at the time of the long-term follow-up assessment

(No separate exclusion criteria are specified, as exclusion follows directly from these inclusion criteria.)

Where it's running

  • Arkin - NPI
    Amsterdam, Netherlands
    Recruiting
  • De Viersprong
    Halsteren, Netherlands
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.