Condition

Arteriovenous Fistula clinical trials and research

• 10Clinical trials
• 35NIH research projects
• 9Countries

Newest Arteriovenous Fistula clinical trials

All recruiting trials (10)

• Apixaban to help arm fistulas mature in people with end-stage kidney disease

  This trial will try a short course of apixaban in adults with end-stage kidney disease getting a new arm arteriovenous fistula to see if it helps the fistula mature for hemodialysis.

  Recruiting Combined military hospital lahore · Lahore, Punjab Province · NCT07559942

• Single-needle distal return for long-term AV fistula care

  This trial tests a single-needle method that draws blood from your arm fistula and returns it through a foot or lower-leg vein to see if it reduces damage and the need for repeat procedures in adults on thrice-weekly hemodialysis.

  Recruiting Suzhou Municipal Hospital of Anhui Province · Suzhou, Anhui · NCT07372027

• Liquid embolic treatment for brain arteriovenous malformations

  This study will test a new liquid embolic agent against the Onyx system in adults (18–80) with brain arteriovenous malformations to see if it is as safe and effective.

  Recruiting MicroPort NeuroTech Co., Ltd. · Shanghai, Shanghai Municipality · NCT07314047

• Velocity pAVF system for creating dialysis fistulas through a small skin puncture

  This trial will test whether the minimally invasive Velocity pAVF system can create a dependable dialysis fistula in adults with kidney failure or those expected to need hemodialysis soon.

  Recruiting at 13 sites Venova Medical · Dothan, Alabama and 12 other locations · NCT07153939

• Comparing drug-coated balloons to plain balloons for treating AVF stenosis

  This study is testing if a special drug-coated balloon works better than a regular balloon for treating narrow spots in blood vessels for patients with arteriovenous fistula stenosis.

  Recruiting Phase 3 Singapore General Hospital · Singapore · NCT06553443

• Comparing drug-coated balloons and cutting balloons for treating arteriovenous fistula stenosis

  This study is testing whether drug-coated balloons or cutting balloons work better and are safer for treating narrowing in arteriovenous fistulas in patients.

  Recruiting at 3 sites RenJi Hospital · Zhengzhou, Henan and 2 other locations · NCT06527963

• Follow-up on the Lifetech Cera Vascular Plug System

  This study is looking to see how well the Lifetech Cera Vascular Plug System works and if it’s safe for people who need treatment for blood vessel issues.

  Recruiting at 9 sites Lifetech Scientific (Shenzhen) Co., Ltd. · Bad Hersfeld and 8 other locations · NCT06099015

• SelfWrap-Assisted Arteriovenous Fistulas for Chronic Kidney Disease

  This study is testing if a new wrap called SelfWrap can make it safer and more effective for people with chronic kidney disease to have a new arteriovenous fistula created.

  Recruiting at 28 sites VenoStent · Bullhead City, Arizona and 27 other locations · NCT06001827

• Predicting Arteriovenous Fistula Maturation Using Inflammatory Markers

  This study is testing if certain inflammation markers can help predict how well arteriovenous fistulas will mature in patients with end-stage renal disease who need dialysis.

  Recruiting National Taiwan University Hospital · Taipei · NCT05136859

• Using the BD® WavelinQ™ EndoAVF System to create arteriovenous fistulas for dialysis patients

  This study is testing a new device to see if it can safely create access points for dialysis in patients with severe kidney disease.

  Recruiting at 15 sites C. R. Bard · La Jolla, California and 16 other locations · NCT04634916

NIH-funded research (35)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Cardiovascular changes after AV fistula creation and how autophagy affects it

  A VA-led project looks at how blood vessel remodeling after AV fistula surgery may be helped by understanding and targeting autophagy.

  NIH research Birmingham VA Medical Center · Birmingham, United States · NIH-11640677

• Nanoparticle delivery to prevent AV fistula narrowing

  A new nanoparticle-based approach aims to prevent AV fistula narrowing in people with kidney failure who rely on dialysis.

  NIH research Pavaj Vascular Corporation · Rochester, United States · NIH-11405688

• Molecular control of arterial-to-vein remodeling in fistula maturation

  This study explores how vein cells change to help arteriovenous fistulas mature, with the aim of improving outcomes for people needing hemodialysis.

  NIH research Augusta University · Augusta, United States · NIH-11377673

• How the protein calprotectin affects healing of dialysis fistulas

  Looking at whether a protein called calprotectin causes narrowing that keeps new dialysis fistulas from becoming usable for people with kidney failure.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11377242

• Improving AV fistula longevity by guiding vein remodeling

  A research project is exploring how to help veins adapt better when used for hemodialysis access so patients have fewer costly procedures.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11369681

• Bioabsorbable wrap to improve AV fistula outcomes

  A new bioabsorbable wrap is being studied to help AV fistula surgery heal better and stay open longer for people needing hemodialysis.

  NIH research Venostent, INC. · Houston, UNITED STATES · NIH-11358673

• AI tool to screen AV fistula stenosis using stethoscope sounds in dialysis patients

  A new AI tool uses sound recordings from a digital stethoscope to screen for narrowing in dialysis fistulas, helping clinicians catch problems earlier.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11333306

• Activating a cell protein to prevent early dialysis fistula failure

  This research tests a drug-like activator of the Mac-1 protein to reduce inflammation and help new dialysis fistulas work better for people with end-stage kidney disease.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11262322

• Helping dialysis fistulas heal and open better in older adults

  This research looks at why dialysis fistulas often don't grow enough in people with kidney failure, especially older adults, and explores ways to help them open and work better.

  NIH research VA Salt Lake City Healthcare System · Salt Lake City, United States · NIH-11247067

• How immune cells and hormones affect dialysis fistula veins

  This work looks at how the immune system and sex hormones change the vein used for dialysis fistulas in people with kidney failure.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11238427

• RAGE–SIRT1 medicines to help dialysis fistulas mature

  This project looks at whether drugs that block RAGE or boost SIRT1 can help newly created dialysis arteriovenous fistulas mature and stay open for people who need hemodialysis.

  NIH research VA Salt Lake City Healthcare System · Salt Lake City, United States · NIH-11206899

• Treatment to keep dialysis fistulas open

  A local nanoparticle therapy delivering active vitamin D aims to stop vein narrowing in people who use arteriovenous fistulas for hemodialysis.

  NIH research Pavaj Vascular Corporation · Rochester, United States · NIH-11194473

• AI-guided 3D ultrasound to reduce needle injuries for people with dialysis fistulas

  An AI-guided 3D ultrasound tool to help dialysis technicians find and use arteriovenous fistulas more safely for people receiving hemodialysis.

  NIH research Sonavex, INC. · Baltimore, UNITED STATES · NIH-11193967

• Improving Arteriovenous Fistulas for Dialysis

  This research explores ways to help arteriovenous fistulas (AVFs) work better and last longer for people who need hemodialysis.

  NIH research Yale University · New Haven, United States · NIH-11141596

• Using AI to detect narrowing in dialysis patients' blood vessels through sound recordings

  This study is testing a new AI tool that listens to sounds from dialysis patients' arteriovenous fistulas to see if it can spot problems like stenosis, and it aims to find out if this tool can be used just as well by trained technicians and patients as the current standard method.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11132384

• Understanding why dialysis access veins fail to mature

  This research looks at how vein cells change after surgery to create a dialysis access, aiming to understand why these access points often don't work well for patients with kidney disease.

  NIH research Augusta University · Augusta, United States · NIH-11128778

• Using biodegradable scaffolds with stem cells to improve vascular access for dialysis patients

  This study is looking at a new way to help improve the success of arteriovenous fistulas (AVFs) for people on hemodialysis by using special materials that can help reduce inflammation and make it easier for doctors to see how well the AVF is working.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11054662

• Using integrin activation to improve the success of dialysis access in kidney disease patients

  This study is looking at a new way to help improve the success of arteriovenous fistulas for people on hemodialysis, by using a special treatment that may reduce inflammation and prevent problems that can cause these important connections to fail.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11019793

• Investigating why arteriovenous fistulas fail in patients with kidney disease

  This study is looking into why some arteriovenous fistulas (AVFs) don’t work well for people on hemodialysis, especially how central venous catheters (CVCs) might cause problems, and it hopes to find ways to help more AVFs succeed.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11011503

• Improving ultrasound imaging to help arteriovenous fistulas mature for dialysis

  This study is looking at new ways to use ultrasound to see how well arteriovenous fistulas (AVFs) are developing for patients on hemodialysis, helping doctors spot any issues early so they can ensure you get the dialysis treatment you need.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-10996083

• How the immune system affects the remodeling of blood vessels used for dialysis.

  This study is looking at how the immune system affects the way blood vessels called arteriovenous fistulas (AVFs) develop in patients on dialysis for kidney disease, with the hope of finding better ways to help these blood vessels work well and improve treatment for patients.

  NIH research Yale University · New Haven, United States · NIH-10983772

• Understanding how arteriovenous fistulas develop problems after creation

  This study is looking into why some arteriovenous fistulas (AVFs), which are important for patients on dialysis, don’t develop as they should, and it hopes to find ways to help more of them work better for those who need them.

  NIH research Birmingham VA Medical Center · Birmingham, United States · NIH-10925548

• Understanding how aging affects the success of vascular access for dialysis patients

  This study is looking at why older patients sometimes have trouble with the creation of arteriovenous fistulas (AVFs) needed for dialysis, and it hopes to find ways to make these procedures more successful so that patients can have a better quality of life.

  NIH research VA Salt Lake City Healthcare System · Salt Lake City, United States · NIH-10924543

• Using AI and 3D ultrasound to improve dialysis access procedures

  This study is testing a new 3D ultrasound system that helps dialysis technicians find blood vessels more easily when starting treatment, with the goal of making the process safer and improving your overall experience during hemodialysis.

  NIH research Sonavex, INC. · Baltimore, UNITED STATES · NIH-10922007

• Investigating a new therapy to improve the maturation of arteriovenous fistulas in older adults

  This study is looking at how specific proteins in blood vessel cells can help improve the growth of arteriovenous fistulas (AVFs) for people on hemodialysis, and it’s testing different small molecules to see if they can make these fistulas work better.

  NIH research VA Salt Lake City Healthcare System · Salt Lake City, United States · NIH-10921808

• Improving the function of arteriovenous fistulas for dialysis patients

  This study is testing a new treatment to help improve the function of arteriovenous fistulas (AVFs) for people on hemodialysis, aiming to prevent problems that can cause these important access points to fail.

  NIH research Pavaj Vascular Corporation · Rochester, United States · NIH-10919089

• Surgery versus inside-the-vessel methods to create dialysis arteriovenous fistulas

  This project compares traditional surgical versus newer endovascular ways of creating arteriovenous fistulas for people who need hemodialysis.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-10913412

• Understanding how blood vessels adapt in arteriovenous fistulas for dialysis

  This study is looking at how certain cells in your veins react to blood flow changes to help improve the way arteriovenous fistulas (AVFs) develop, which is important for people on dialysis due to kidney disease.

  NIH research Augusta University · Augusta, United States · NIH-10871833

• Using nanotechnology to improve the success of arteriovenous fistulas for dialysis patients

  This study is looking at how certain proteins and special tiny drug carriers can help improve the growth of arteriovenous fistulas (AVFs) for people on hemodialysis, aiming to make the process easier and more effective for patients.

  NIH research University of Utah · Salt Lake City, United States · NIH-10839381

• Comparing outcomes of two methods for creating access points for dialysis.

  This study is looking at two ways to create access points for dialysis—one that's been used for a long time and a newer method—to see which one works better and has fewer problems for people needing dialysis.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-10839297

• Investigating how autophagy affects the maturation of arteriovenous fistulas for dialysis.

  This study is looking into why some arteriovenous fistulas (AVFs) don’t develop as they should for people on hemodialysis, and it aims to find ways to help them mature better by understanding how certain cellular processes work, especially for those with chronic kidney disease.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-10831413

• Improving the success of arteriovenous fistulas for dialysis patients

  This study is looking at ways to make arteriovenous fistulas (AVFs) work better for people on hemodialysis by understanding how veins can adapt and improve their function, which could help patients have more successful treatments and fewer surgeries.

  NIH research Yale University · New Haven, United States · NIH-10813093

• Comparing two methods for creating vascular access for kidney dialysis

  This study is looking at two ways to create a special connection in your blood vessels that helps people with kidney disease get dialysis, comparing traditional surgery with a newer method to see which one works better and is safer for you.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-10709628

• Understanding barriers to using arteriovenous fistulas in black patients on dialysis

  This study is looking into why black patients with kidney failure are less likely to use a certain type of access for dialysis compared to white patients, and it aims to gather insights from both patients and healthcare providers to help improve care for everyone.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-10551916

• New approach to improve the success of arteriovenous fistulas for dialysis

  This study is looking into why some arteriovenous fistulas (AVFs) don’t develop properly for dialysis and is testing new treatments that could help them mature better, which could be really helpful for patients who rely on dialysis.

  NIH research Western University of Health Sciences · Pomona, United States · NIH-10457852

Related topics

Quick answers

How many Arteriovenous Fistula clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in China (3 trials), United States (3 trials), Pakistan (1 trial), Taiwan (1 trial), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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