Surgery versus inside-the-vessel methods to create dialysis arteriovenous fistulas
Comparing surgical and endovascular arteriovenous fistula creation
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10913412
This project compares traditional surgical versus newer endovascular ways of creating arteriovenous fistulas for people who need hemodialysis.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10913412 on ClinicalTrials.gov |
What this research studies
If you need a new arteriovenous fistula (the blood vessel connection used for hemodialysis), this research will look at outcomes after the usual surgical operation versus newer devices that create the fistula from inside the blood vessels. The team will collect procedural and short-term outcome data on patients treated with either approach to learn which patients do better with each method. They will also document how often patients meet the anatomic requirements for the endovascular devices, since not everyone is eligible for those methods. The goal is to use these results to plan a larger trial that would directly guide patient and clinician choices about fistula creation.
Who could benefit from this research
Good fit: Adults with end-stage kidney disease who need a new arteriovenous fistula for hemodialysis and who meet the anatomic criteria for surgical or endovascular AVF creation would be the ideal candidates.
Not a fit: People who do not need dialysis access, who are not candidates for either surgical or endovascular fistula creation, or whose blood vessel anatomy makes endovascular devices unsuitable may not benefit from this work.
Why it matters
Potential benefit: Results could help patients and doctors choose the approach that leads to better initial success, fewer additional procedures, and fewer complications when creating dialysis access.
How similar studies have performed: Early industry-sponsored trials and small studies showed the endovascular devices can work and they are FDA-approved, but no large prospective head-to-head comparisons with surgical AVF have been done.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WOO, KAREN — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: WOO, KAREN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.