Predicting Arteriovenous Fistula Maturation Using Inflammatory Markers

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the relationship between inflammation and pre-existing venous fibrosis in predicting the maturation of arteriovenous fistulas (AVFs) in patients with end-stage renal disease. It aims to analyze blood and tissue samples to assess the impact of these factors on AVF success rates. The research focuses on understanding how perivascular fat around the cephalic vein may influence AVF maturation, which is critical for effective hemodialysis access. By identifying these predictors, the study seeks to improve outcomes for patients requiring vascular access for dialysis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age of 20 and older adult patients.
2. preoperatively clinical and ultrasound assessment of the arm vessels are visible for the creation of a native HDAVF that include：the augmented diameters of the veins is \> 2.0 mm and the diameter of the radial artery is\> 2.0 mm. Besides, there is no obvious stenosis of vessels in the forearm.

Exclusion Criteria:

1. The patient refused to join the study
2. serious heart failure (Physicians identify insufficient cardiac output that may affect sacral blood flow development after surgery)
3. Unconsciousness
4. Bedridden for long time
5. systemic lupus erythematosus(SLE), or other known autoimmune diseases
6. The physician excludes the possibility of creating a wrist HDAVF before surgery
7. Surgeon preoperatively identifies vessel inadequacy for the creation of a wrist HDAVF
8. Choose a site other than the wrist for surgery
9. Unexpected complications happen during the surgery that prevent the completion of a wrist HDAVF

Where it's running

• National Taiwan University Hospital
  Taipei, Taiwan Recruiting

Study contacts

• Study coordinator: Chih-Yang Chan, PhD
• Email: chanchihyang@gmail.com
• Phone: +886972651147

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Apixaban to help arm fistulas mature in people with end-stage kidney disease

  This trial will try a short course of apixaban in adults with end-stage kidney disease getting a new arm arteriovenous fistula to see if it helps the fistula mature for hemodialysis.

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• Single-needle distal return for long-term AV fistula care

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• Liquid embolic treatment for brain arteriovenous malformations

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  Recruiting MicroPort NeuroTech Co., Ltd. · Shanghai, Shanghai Municipality · NCT07314047

• Velocity pAVF system for creating dialysis fistulas through a small skin puncture

  This trial will test whether the minimally invasive Velocity pAVF system can create a dependable dialysis fistula in adults with kidney failure or those expected to need hemodialysis soon.

  Recruiting at 13 sites Venova Medical · Dothan, Alabama and 12 other locations · NCT07153939

• Comparing drug-coated balloons to plain balloons for treating AVF stenosis

  This study is testing if a special drug-coated balloon works better than a regular balloon for treating narrow spots in blood vessels for patients with arteriovenous fistula stenosis.

  Recruiting Phase 3 Singapore General Hospital · Singapore · NCT06553443

• Comparing drug-coated balloons and cutting balloons for treating arteriovenous fistula stenosis

  This study is testing whether drug-coated balloons or cutting balloons work better and are safer for treating narrowing in arteriovenous fistulas in patients.

  Recruiting at 3 sites RenJi Hospital · Zhengzhou, Henan and 2 other locations · NCT06527963

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.