Sponsor or institution
Clinical trials and research at University of Illinois Chicago
As of November 12, 2026, Find a Trial lists 94 clinical trials run by University of Illinois Chicago that are recruiting, at sites in 4 countries (most in United States (91), South Africa (1), Senegal (1)). By phase: Phase 2 (19), Phase 4 (3), Phase 1 (3), Early Phase 1 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 94Clinical trials
- 4Countries
Newest trials
All recruiting trials (94)
-
Bridge & Friends: MedDiet with Social Networks for obesity in older adults
This study tests whether adding a social network component to a Mediterranean diet with weight loss helps older adults with obesity lose more weight and improve diet and activity.
-
BRIDGE: Embedding consumer mHealth tools into cardiac rehab
This study tests whether adding a mobile health tool to standard center-based cardiac rehab helps heart patients stay active and follow healthy habits.
-
Meditation app feasibility for youth in the juvenile legal system
This study tests whether teens in probation can stick with a 1-month meditation app, comparing Bodhi AIM to a healthy-choices app across four juvenile programs.
-
Tele-Cross Education for severe stroke
This study tests whether home-based, remotely guided training of the unaffected leg can help improve brain and nerve function and movement in people with severe stroke.
-
Elranatamab consolidation for newly diagnosed plasmablastic lymphoma
This study tests whether giving Elranatamab after initial chemotherapy can help patients with plasmablastic lymphoma, with or without HIV, stay in remission.
-
Targeted physical activity for frail pancreatic cancer patients on neoadjuvant chemotherapy
This study tests a supervised, low‑intensity resistance exercise program to see if it helps frail or pre‑frail adults with pancreatic cancer who are receiving neoadjuvant chemotherapy.
-
Olanzapine added to chemotherapy for gastric cancer to help keep weight and appetite up
This study tests whether adding low-dose olanzapine to standard neoadjuvant chemotherapy helps patients with gastric cancer maintain weight and appetite during treatment.
-
Impact of Delay on Wireless Hearing Assistive Devices
This study tests how much delay in wireless remote microphones people can tolerate when using assistive listening devices.
-
Remotely Delivered Pilates for MS: Walking, Balance, Fatigue, Mood and Quality of Life
A 16-week remote Pilates program will be tested to see if it helps walking, balance, fatigue, pain, mood, thinking, and quality of life for people with multiple sclerosis who can participate from home.
-
Postpartum mood and alcohol use: a CM-PST approach for new mothers
This study tests whether a six-week CM-PST program helps reduce depressive symptoms and alcohol use in new mothers within the first year after birth.
-
SENTINL-1: Patient-reported outcomes after AI-inferred lung cancer risk
This project will test giving AI-based 3-year lung cancer risk results to people aged 50–80 who are eligible for low-dose CT screening to see if it changes their feelings and choices about screening.
-
Resilience-building tool to help with advance care planning
This study tests a web-based resilience program called ROCKS to see if it helps adults with advanced cancer and their family caregivers finish advance directives better than usual care.
-
Precision lung cancer screening using AI risk scores and blood biomarkers
This project will test whether the Sybil AI tool and optional blood tests can better predict lung cancer risk for people aged 50–80 getting low-dose CT scans, including those who meet expanded screening rules beyond current USPSTF guidance.
-
On Track for Wellness: a stepped-wedge program to boost sleep and activity in first-episode psychosis
This program tests whether using Fitbit trackers, health education, and goal setting helps people with first-episode psychosis sleep better and move more.
-
Time‑restricted eating (8‑hour window) during chemotherapy for breast cancer: feasibility and acceptability
This trial will test whether eating all daily food within an 8‑hour window is practical and acceptable for people starting chemotherapy for stage I–III breast cancer (and some stage IV with oncologist approval).
-
Home-based functional balance program for people with multiple sclerosis
This project will test whether a home-based functional balance program helps adults with multiple sclerosis improve physical and cognitive function and daily activities.
-
Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control
A 24-week program tests whether a food-as-medicine approach (FIM+DASH) helps adults with hypertension and obesity lower blood pressure and improve eating patterns compared with usual care.
-
PRONTO-EYE rideshare program to help people with diabetic retinopathy get to eye appointments
This project tests whether a rideshare transportation program (PRONTO‑EYE) helps people with diabetic retinopathy who have Medicaid get to ophthalmology appointments more often.
-
POLARIS — Ablative radiotherapy with immunotherapy for people with multiple metastatic lesions
This pilot tests whether giving focused high-dose radiation to up to 10 metastatic tumors while patients are on immunotherapy helps people with advanced solid tumors who have 3–10 metastases.
-
Helping caregivers prevent repeat dental surgery for preschool children with severe tooth decay
This program tests whether giving caregivers skills and support can help preschool children who need dental surgery avoid repeat cavities and future surgeries.
-
CKD Awareness, Referrals, Education, and Support for Early-Stage CKD in Adults with Diabetes
This intervention tests whether education, motivational support, and social backing delivered virtually can help adults with diabetes and early CKD slow kidney decline and stay engaged with care.
-
Empagliflozin to protect kidney function in sickle cell anemia with albuminuria
This study tests whether taking empagliflozin can slow kidney decline in people with sickle cell anemia and albuminuria.
-
UIC multi-ethnic dilated cardiomyopathy registry
This project will collect genetic and social data from adults with dilated cardiomyopathy, especially African American and Hispanic/Latino patients, to see if certain genes and social factors explain worse outcomes.
-
Fluorescence-guided suction monitoring to detect tumor tissue during brain surgery
This trial will test a device that detects 5-ALA fluorescence in surgical suction to help surgeons find tumor tissue during adult glioma surgery.
-
Prison-Based HIV Partner Notification (APN vs. self-notification)
This study tests whether assisted partner notification helps people with HIV in prison tell their partners about possible exposure and connect partners with HIV testing and care.
-
Task-specific balance training to reduce falls in older adults
This study will test whether a new task-specific balance training helps community-dwelling older adults at risk of falling avoid slips, trips, and reduce real-life falls.
-
Cognitive behavioral therapy for insomnia in adults with type 1 diabetes
This trial will test whether virtual cognitive behavioral therapy for insomnia (CBT-I) helps adults with type 1 diabetes sleep better and improves blood sugar control and quality of life.
-
Probiotic to improve iron levels and blood health during pregnancy
This trial will test whether taking the probiotic Lactiplantibacillus plantarum 299v can help pregnant people at risk of iron deficiency improve their iron and blood levels.
-
Progressive muscle relaxation plus walking to reduce fatigue in adults on dialysis
This program will try progressive muscle relaxation combined with regular walking to see if it reduces fatigue for adults receiving in-center hemodialysis.
-
Thigh blood-flow restriction for knee osteoarthritis and low back pain
This trial will test whether repeated brief full thigh blood-flow restriction every other day for two weeks helps people over 50 with knee osteoarthritis and low back pain improve function.
-
Evaluating a meditation app for youth on probation
This study is testing whether a meditation app can help young people on probation in Cook County improve their mental health and reduce cannabis use over a month.
-
Improving diabetes care using data from sensors and the environment
This study is testing if using data from health records, wearable devices, and environmental sensors can help improve diabetes care for people with type 2 diabetes living in vulnerable neighborhoods.
-
Peer navigators helping adults with newly acquired physical disabilities live independently
A remote peer navigator program tests whether matched peers can boost social support and quality of life for adults who recently became disabled and are returning to community living.
-
Topical mesenchymal stem cell secretions for persistent corneal epithelial defects
This trial will test whether eye drops made from bone-marrow mesenchymal stem cell secretions can help adults whose corneal epithelial defects have not healed with standard treatments.
-
Using social networks to find people with undiagnosed HIV and reduce stigma
This project will test whether asking adults newly diagnosed with HIV to recruit friends, family, and acquaintances can locate people with undiagnosed HIV and reduce HIV-related stigma among testing-avoidant adults in the Msunduzi region of KwaZulu-Natal.
-
Train friends and family to be harm‑reduction champions for people who use opioids
This project will train non‑using friends and family of people who use opioids on Chicago’s West Side to act as harm‑reduction champions and see if that helps their loved ones get naloxone, fentanyl test strips, and other support.
-
Intensity-modulated total marrow irradiation for high-risk blood cancers
This study is testing a new type of radiation treatment combined with standard chemotherapy to see if it helps people with high-risk blood cancers feel better after receiving stem cell transplants.
-
Digital intervention for obesity and depression in older racial and ethnic adults
This study is testing a digital program that helps older adults from racial and ethnic backgrounds manage their weight and depression with the support of a virtual coach and other tools.
-
Improving sleep regularity to reduce cardiovascular risks in type 1 diabetes
This study is trying to see if improving sleep patterns can help adults with type 1 diabetes lower their risk of heart problems.
-
Clemastine to boost brain white matter and antidepressant response in older adults with depression
This study tests whether adding clemastine to standard antidepressant treatment helps older adults with depression by improving brain white matter and reducing symptoms.
-
OncoChoice-guided chemotherapy for metastatic non-small cell lung cancer (second-line and beyond)
This pilot will try using OncoChoice testing to help pick chemotherapy for adults with metastatic NSCLC who need second-line or later treatment.
-
Testing a mentoring program for youth mental health
This study is testing whether a mentoring program can improve the mental health of kids aged 9 to 16 from low-income families who are already getting mental health support.
-
Optimizing Biomarkers for Neoadjuvant Therapy in HER2-positive Breast Cancer
This study is testing if a special test on breast cancer samples can help doctors choose the best chemotherapy for adults with early-stage HER2-positive breast cancer.
-
Exercise rehabilitation for wheelchair users with multiple sclerosis
This study tests a personalized exercise program for wheelchair users with multiple sclerosis to see if it can help them feel stronger and improve their daily activities.
-
Glycyrrhizin treatment for prostate cancer before surgery
This study is testing whether a treatment called Glycyrrhizin can help men with untreated prostate cancer feel better before their surgery.
-
Impact of Targeted Physical Activity on Dialysis Patients
This study is testing if a personalized exercise program can help people on dialysis or with severe kidney disease feel better and improve their health over a year.
-
Improving balance and cognition in people with Multiple Sclerosis
This study is testing a new balance training program to see if it can help people with Multiple Sclerosis improve their physical and thinking skills.
-
Magnetic device for treating corneal exposure due to eyelid paralysis
This study is testing a new magnetic device to help people with eyelid paralysis keep their eyes closed and prevent serious eye problems.
-
Empowering Black male caregivers to support Black girls' sexual health
This study tests a new program that helps Black male caregivers support Black girls in staying healthy and safe from STIs and sexual violence.
-
Peer-led family support intervention for refugee families
This study tests a new support program led by peers to help refugee families in Chicago improve their mental health and strengthen their family connections.
-
Improving executive function in young children through parenting support
This study is testing if a parenting program can help improve thinking skills in young children with behavior problems to see if it also reduces their disruptive behaviors.
-
Comparing robotic and laser surgery for prostate enlargement treatment
This study is testing whether robotic surgery or laser surgery is better for treating men with prostate enlargement who haven't found relief from other treatments.
-
Exploring the Gut Microbiome's Role in Pain After Kidney Transplant
This study looks at how the bacteria in the gut might affect chronic pain in people who have had a kidney transplant, and whether diet and stress play a role in this connection.
-
Mobile health intervention for heart failure patients
This study is testing two mobile health tools to see if they can help people with chronic heart failure take better care of themselves and reduce hospital visits.
-
Using abemaciclib with endocrine therapy for early-stage breast cancer
This study is testing if a new way of giving abemaciclib with hormone therapy can help people with high-risk early-stage breast cancer avoid severe side effects and stay on their treatment longer.
-
Comparing reactive balance training with and without electrical stimulation for stroke recovery
This study is testing whether adding electrical stimulation to balance training can help people who have had a stroke improve their balance better than training without it.
-
Phase II trial of CMC regimen for early stage breast cancer
This study is testing a new combination of oral medications for people with early-stage breast cancer to see if it helps them manage their condition safely and effectively.
-
Mindful walking program for older South Asian caregivers of individuals with cognitive disabilities
This study is testing a 12-week mindful walking program to see if it can help older South Asian caregivers of people with cognitive disabilities feel less stressed and improve their mental sharpness.
-
Improving mobility and function after leg amputation
This study is testing if using a blood pressure cuff can help people who have had a leg amputated get stronger and walk better.
-
Home-based functional electrical stimulation training for chronic stroke patients
This study is testing if a home-based electrical stimulation program can help people who have had a stroke improve their walking and balance over 12 weeks.
-
Improving health and social participation for people with disabilities post-COVID
This study is testing a new program called ENGAGE to see if it can help reduce social isolation and improve community involvement for people with disabilities who have been affected by COVID-19.
-
Testing a new intervention to help young adults stop drinking alcohol
This study is testing a new online program to help young adults aged 18-24 stop drinking alcohol and see if it works better than just providing rewards for not drinking.
-
Comparing sedation methods for awake fiberoptic intubation
This study tests two different sedation methods during awake fiberoptic intubation to see which one helps patients feel more comfortable and stable when they have difficult airways.
-
Using stem cells to treat corneal ulcers
This study is testing if injections of stem cells from bone marrow can help heal stubborn corneal ulcers and improve vision for people with this condition.
-
Bringing genetic testing for hereditary breast and colon cancer into community health centers
This project tests whether a mainstream genetic testing approach versus an enhanced usual-care approach increases genetic testing among adults at risk for hereditary breast or colon cancer seen in urban community health centers.
-
Combining cabozantinib and pembrolizumab for lung cancer maintenance therapy
This study is testing if combining cabozantinib with pembrolizumab can help people with advanced squamous non-small cell lung cancer stay healthy after their initial treatment.
-
Improving orthodontic treatment with remote monitoring and AI
This study is testing if using remote monitoring and AI can make orthodontic treatment with clear aligners more effective and convenient for patients by reducing office visits and improving their experience.
-
Patient navigation program for cervical cancer screening in Senegal
This study is testing a new support program to help women in Senegal get screened for cervical cancer and access treatment more easily.
-
Helping Latinas access breast cancer care
This study is trying to help Latina women at higher risk for breast cancer by giving them personalized support and education over the phone about breast cancer care, diet, and exercise.
-
Using probiotics in nasal irrigation to treat chronic sinusitis
This study is testing if using a probiotic nasal rinse can help people with chronic sinusitis feel better after they've had sinus surgery, compared to using a regular saline rinse.
-
Maintenance treatment for multiple myeloma after stem cell transplant
This study is testing if a combination of isatuximab and lenalidomide can help people with multiple myeloma who still have traces of cancer after a stem cell transplant.
-
Navigating Mental Health Services for Children in Urban Poverty
This study is testing if having community helpers can make it easier for African American and Latinx kids living in urban poverty to get the mental health care they need compared to just waiting for help.
-
Time restricted eating during chemotherapy for breast cancer
This study is testing if a specific eating schedule combined with a healthy diet can help women with breast cancer feel better during chemotherapy and manage side effects.
-
Culturally tailored lifestyle counseling for pregnant African American women
This study is testing a special lifestyle counseling program for pregnant African American women to see if it helps them manage their blood sugar and improve their health during pregnancy.
-
Mindfulness program for African-Americans with type 2 diabetes
This study is testing a mindfulness meditation program to see if it can help African-American adults with type 2 diabetes sleep better and feel less stressed.
-
Investigating how adiposomes affect blood vessel function in obesity and diabetes
This study is testing how tiny particles from fat tissue affect blood vessel health in people with obesity and diabetes, while also seeing if exercise can help improve this issue.
-
Stopping maintenance therapy in patients with minimal residual disease-negative multiple myeloma
This study is testing whether patients with minimal residual disease-negative multiple myeloma can safely stop their maintenance therapy after a stem cell transplant to see how it affects their health and quality of life.
-
Evaluating the effects of exercise therapy on veterans' health
This study tests whether a specific exercise program can help U.S. veterans with chronic pain, fatigue, and depression feel better physically and mentally.
-
Analysis of ALS patient tissues and registry
This study is trying to gather information from people with ALS to better understand the disease and find new ways to treat it.
-
Exercise programs for depression in people with multiple sclerosis
This study is testing whether a structured exercise program or a stretching program can help people with multiple sclerosis and depression feel better and improve their health.
-
Using electrical stimulation to improve balance and reduce fall risk in stroke patients
This study is testing if using electrical stimulation on leg muscles can help stroke patients improve their balance and reduce their risk of falling.
-
Training to improve balance and cognitive function in older adults with mild cognitive impairment
This study is testing a new training program that helps older adults with mild cognitive impairment improve their balance and thinking skills to reduce their risk of falling.
-
Preoperative low dose azacitidine for high-risk early stage breast cancer
This study is testing if a low dose of azacitidine can boost the immune response in patients with high-risk early stage breast cancer before they have surgery.
-
Using melatonin to improve sleep in patients with diabetic retinopathy
This study tests if taking melatonin can help people with diabetic retinopathy sleep better over eight weeks.
-
Using brain stimulation to improve walking after stroke
This study is testing if using brain stimulation along with treadmill and ankle training can help stroke survivors walk better.
-
Using convalescent plasma to treat COVID-19 patients
This study is testing if giving convalescent plasma from recovered COVID-19 patients can help people over 40 who are hospitalized with the virus feel better compared to those receiving standard care.
-
Training to improve balance and prevent falls
This study is testing different training devices to see if they can help healthy young adults, healthy older adults, and stroke survivors improve their balance and reduce the risk of falls.
-
Intensity Modulated Total Marrow Irradiation for Acute Leukemia and MDS
This study is testing a new type of radiation treatment before a stem cell transplant to see if it helps people with acute leukemia or myelodysplastic syndromes do better.
-
Comparing transdermal granisetron to ondansetron for nausea in stem cell transplant patients
This study is testing whether a skin patch with granisetron can help reduce nausea from chemotherapy better than the standard intravenous ondansetron in patients getting stem cell transplants.
-
Lidocaine infusion for patients with pancreatic cancer
This study is testing if giving lidocaine through an IV can change the behavior of cancer cells in the blood of patients with pancreatic cancer who are having surgery.
-
Using virtual reality dance therapy to improve physical function in stroke patients
This study is testing if virtual reality dance therapy can help stroke patients improve their physical and mental abilities better than traditional rehab methods.
-
Examining DNA Methylation's Role in Obesity and Vascular Health
This study is testing if changes in DNA related to obesity can lead to heart problems and whether exercise can help improve these issues for people who are overweight.
-
HLA-haploidentical stem cell transplantation for aggressive sickle cell disease
This study is testing a new type of stem cell transplant to see if it can help people with severe sickle cell disease feel better.
-
Testing antiarrhythmic drugs for atrial fibrillation based on genetics
This study is testing if two different heart medications can help people with frequent atrial fibrillation based on their genetic makeup.
Quick answers
How many clinical trials run by University of Illinois Chicago are recruiting right now?
94, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in United States (91 trials), South Africa (1 trial), Senegal (1 trial), Indonesia (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 19, Phase 4: 3, Phase 1: 3, Early Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.