Testing a new intervention to help young adults stop drinking alcohol

StuDy AimED at Increasing AlCohol AbsTinEnce (DEDICATE)

Not applicable Interventional University of Illinois at Chicago · NCT05778734

This study is testing a new online program to help young adults aged 18-24 stop drinking alcohol and see if it works better than just providing rewards for not drinking.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment104 (estimated)
Ages18 Years to 24 Years
SexAll
SponsorUniversity of Illinois at Chicago Academic / other
Locations1 site (Chicago, Illinois)
Trial IDNCT05778734 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the feasibility and acceptability of a new intervention called CM-PST for young adults with Alcohol Use Disorder (AUD). The study will enroll participants aged 18-24 who meet AUD criteria and will assess their experiences with the intervention through surveys and interviews. Participants will receive the CM-PST intervention via videoconferencing over 12 weeks, with follow-up assessments at 3 and 6 months to measure efficacy. The trial includes both a single-arm pre/post study and a randomized control trial to compare CM-PST with a control group receiving only contingency management.

Who should consider this trial

Good fit: Ideal candidates are young adults aged 18-24 who currently consume alcohol at least once a week and meet the criteria for mild, moderate, or severe Alcohol Use Disorder.

Not a fit: Patients who have recently participated in substance use treatment or are currently taking medications for Alcohol Use Disorder may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve treatment outcomes for young adults struggling with alcohol use.

How similar studies have performed: Other studies have shown promise with similar interventions, but this specific approach is novel in its integration of CM-PST for young adults with AUD.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male and female young adults aged 18-24 yr
* English-speaking
* Current alcohol use greater or equal to 1 day/week via phone screening, and meet criteria for (past year) mild, moderate or severe AUD on the AUDIT and AUDADIS surveys.
* Completion of written informed consent
* Baseline screening study visit.

Exclusion Criteria:

* Participation in past 6 mo. in AUD or substance use treatment
* Current use of medications used to treat AUD (e.g., naltrexone)
* Lifetime DSM-5 diagnosis of schizophrenia, bipolar disorder, or any psychotic disorder.
* Current use of psychoactive drugs, determined by positive drug toxicology screen
* Conditions (e.g., tic disorder) that would interfere with psychophysiological indices of reward functioning
* Pregnancy or intention to become pregnant
* Additional exclusion criteria pertaining to fMRI scan in R00 phase only: a) bodily ferrous metals (e.g., aneurysm clips, shrapnel/retained particles) or b) claustrophobia, inability to tolerate small enclosed spaces.

Where this trial is running

Chicago, Illinois

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Alcohol Use Disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.