Analysis of ALS patient tissues and registry
Official title: Analysis of Human ALS Tissues and Registry of ALS Patients
Run by University of Illinois Chicago · NCT05067179 · Data updated 2026-11-12
This study is trying to gather information from people with ALS to better understand the disease and find new ways to treat it.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | University of Illinois Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Status | Recruiting |
| Started | September 1, 2020 |
| Main results expected | January 1, 2030 |
| Study ends | January 1, 2030 |
| Registry record updated | July 8, 2026 |
| Trial ID | NCT05067179 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 with an established diagnosis of ALS who can provide informed consent.
✕Probably not a fit
Patients under 18 or those without a diagnosis of ALS will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This research focuses on understanding Amyotrophic Lateral Sclerosis (ALS) by collecting data from patients through physical examinations, electrodiagnostic testing, and MRI scans. Patients will consent to have their information entered into a database to monitor disease progression and contribute to research efforts. Additionally, a separate consent will allow for postmortem tissue collection to facilitate in-depth cellular and molecular analyses. The goal is to identify reliable markers of disease progression and potential treatment avenues.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of ALS and the development of effective treatments.
How similar studies have gone: While there have been various studies on ALS, this approach of combining premortem and postmortem analyses is relatively novel and aims to fill significant gaps in understanding the disease.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over the age of 18 * Established diagnosis of ALS * Able and willing to give written informed consent and must authorize release and use of protected health information Exclusion Criteria: * Patients below the age of 18 * No diagnosis of ALS
Where it's running
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University of Illinois at Chicago
Chicago, Illinois, United States Recruiting
Study contacts
- Principal investigator: Jeffrey Loeb, MD — University of Illinois Chicago
- Study coordinator: Ayo Fasawe
- Email: afasawe@ilstu.edu
- Phone: 312-413-7908
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.