Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Resilience-building tool to help with advance care planning

Official title: Facilitating Advance Care Planning Discussions Between Patients With Advanced Cancer and Their Family Caregivers Using a Resilience-Building Intervention: A Randomized Controlled Trial.

Run by University of Illinois Chicago · NCT07428278 · Data updated 2026-11-12

This study tests a web-based resilience program called ROCKS to see if it helps adults with advanced cancer and their family caregivers finish advance directives better than usual care.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment152 (estimated)
SponsorUniversity of Illinois Chicago
Academic / other
Locations1 site (Chicago, Illinois)
StatusRecruiting
StartedJune 9, 2026
Main results expectedMay 31, 2028
Study endsJuly 31, 2028
Registry record updatedOctober 8, 2026
Trial IDNCT07428278 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal participants are adults with stage 3–4 cancer and a willing family caregiver who can use the internet and communicate in English.

Probably not a fit

Patients who are not interested in online interventions or do not have an English-lacunae-compatible caregiver may derive less benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial at a cancer center will evaluate the feasibility, acceptability, and usability of the ROCKS web-based resilience intervention for both patients with advanced cancer and their family caregivers, compared with usual care. It will look at preliminary efficacy on completion of advance directives and explore how resilience influences self-efficacy, optimism, communication, coping, anxiety, and depression using a dyadic analysis. The study targets patients 18 or older with stage 3 or 4 cancer and a willing caregiver, all requiring basic English literacy and internet access. The primary focus is on advancing ACP engagement and resilience-linked outcomes in a dyadic patient–caregiver pair.

Why it matters

Potential benefit: If successful, ROCKS could help more patients complete advance directives and improve resilience and well-being for both patients and caregivers.

How similar studies have gone: Prior resilience or ACP interventions show promise, but this exact web-based ROCKS approach in this dyadic cancer context is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Eligible patients will (1) be ≥ 18 years of age; (2) be diagnosed with stage 3 or 4 cancer; and (3) have a family caregiver who is willing to participate.
* Eligible family caregivers will be ≥ 18 years of age. All participants must be able to read, write, and speak English with minimal assistance from others and have access to the internet on a smartphone, laptop, or computer.

Exclusion Criteria:

* Patient participants will be ineligible if they have (1) a Short Portable Mental Status Questionnaire (SPMSQ) score \< 8; or (2) have completed any form of advance directive.

Where it's running

  • University of Illinois Chicago
    Chicago, Illinois, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.