Clinical trial Recruiting at 1 site Interventional Ages 12 to 70

Improving orthodontic treatment with remote monitoring and AI

Official title: Optimizing Clear Aligners Efficiency With Remote Dental Monitoring and Artificial Intelligence Algorithms

Run by University of Illinois Chicago · NCT05573308 · Data updated 2026-11-12

This study is testing if using remote monitoring and AI can make orthodontic treatment with clear aligners more effective and convenient for patients by reducing office visits and improving their experience.

More Malocclusion trials

Quick facts

Study typeInterventional
Ages12 Years to 70 Years
SexAll
Enrollment12 (estimated)
SponsorUniversity of Illinois Chicago
Academic / other
Locations4 sites (Antioch, Illinois and 3 other locations)
StatusRecruiting
StartedOctober 17, 2022
Main results expectedDecember 30, 2028
Study endsDecember 30, 2029
Registry record updatedJuly 8, 2026
Trial IDNCT05573308 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients aged 12 and older seeking clear aligner treatment for dental alignment without the need for extractions.

Probably not a fit

Patients with systemic diseases, active periodontal disease, or those requiring fixed appliances will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of Remote Dental Monitoring in orthodontic treatment using clear aligners. It aims to determine how this technology can optimize the rate of aligner changes, reduce the number of in-office appointments, and enhance patient satisfaction. The study will compare treatment outcomes between traditional in-office approaches and those utilizing remote monitoring, focusing on treatment effectiveness, cost-effectiveness, and patient compliance. The investigators hypothesize that remote monitoring will maintain treatment quality while improving patient engagement and oral hygiene.

Why it matters

Potential benefit: If successful, this approach could lead to more efficient orthodontic treatments and improved patient outcomes.

How similar studies have gone: While the use of remote monitoring in orthodontics is emerging, this specific application with AI algorithms is relatively novel and has not been extensively tested in clinical settings.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who request clear aligner treatment with the sole aim of correcting dental alignment.
* Patients must be 12 years old or older.
* Complete permanent dentition (excluding third molars).
* Non-extraction treatment,
* Upper or lower labial segment crowding. malocclusion to be treated with more than 20 Clear Aligners.

Exclusion Criteria:

* Patients with systematic diseases or syndromes
* Patients with a history or current use of Bisphosphonates
* Patients with current use of nonsteroidal anti-inflammatory drugs (NSAIDs)
* Active periodontal disease
* Presence of dental prostheses,
* The presence of dental anomalies (7) The treatment combined with fixed appliances or other auxiliary appliances.

Where it's running

  • Department of Orthodontics, College of Dentistry University of Illinois Chicago
    Chicago, Illinois, United States
    Recruiting
  • Orthodontic Specialists of Lake County (Antioch)
    Antioch, Illinois, United States
    Suspended
  • Orthodontic Specialists of Lake County (Grayslake)
    Grayslake, Illinois, United States
    Suspended
  • Orthodontic Specialists of Lake County (Gurnee)
    Gurnee, Illinois, United States
    Suspended

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.