Improving sleep regularity to reduce cardiovascular risks in type 1 diabetes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the relationship between sleep regularity and cardiovascular disease risk in adults with type 1 diabetes (T1D). It aims to understand how enhancing sleep stability through behavioral interventions can improve glycemic control and reduce cardiovascular risks. The study will involve a 4-week intervention targeting sleep stability in 80 participants, examining the mechanisms by which sleep impacts metabolic health. The findings could provide insights into effective strategies for managing T1D and associated cardiovascular risks.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults 18-50 years with a clinical diagnosis of T1D for at least one year
* Report habitual sleep irregularity ≥1 hour/week
* Desire to improve sleep, and own a smartphone (Android or iPhone)

Exclusion Criteria:

* Self-reported A1C within the past 6 months ≥10%
* insomnia symptoms defined as Insomnia Severity Index score ≥15
* history of restless leg syndrome
* history of severe hypoglycemia (defined as hypoglycemic episode that results in loss of consciousness, seizure, or requiring emergency room visit or hospitalization) within the past 6 months
* rotating shift or night work or routinely sleeping after 3 AM.
* use of sleep medications/aids, significant medical comorbidities (such as heart failure, cirrhosis, chronic obstructive pulmonary disease requiring oxygen, active treatment for cancer, on renal replacement therapy \[dialysis\])
* depression (Patient Health Questionnaire 8 \[PHQ-8\] score ≥15)
* history of stroke with neurological deficits
* pregnant, breast feeding, or planning pregnancy, as sleep and glucose are known to change during pregnancy and breastfeeding.
* Allergy to lidocaine Participants who passed the first screen by phone will be scheduled for a consenting visit at UIC

Where it's running

• University of Illinois Chicago
  Chicago, Illinois, United States Recruiting

Study contacts

• Study coordinator: Pamela Martyn-Nemeth, PhD
• Email: pmartyn@uic.edu
• Phone: 312-996-7903

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.