Comparing robotic and laser surgery for prostate enlargement treatment
Official title: Randomized Controlled Trial Comparing Single Port Simple Prostatectomy and Laser Enucleation of the Prostate for Benign Prostatic Hyperplasia
Run by University of Illinois Chicago · NCT06224218 · Data updated 2026-11-12
This study is testing whether robotic surgery or laser surgery is better for treating men with prostate enlargement who haven't found relief from other treatments.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 88 Years |
| Sex | Men only |
| Enrollment | 116 (estimated) |
| Sponsor | University of Illinois Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Status | Recruiting |
| Started | January 15, 2024 |
| Main results expected | January 15, 2027 |
| Study ends | August 15, 2027 |
| Registry record updated | May 16, 2024 |
| Trial ID | NCT06224218 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults diagnosed with symptomatic BPH who have failed conservative treatment options.
✕Probably not a fit
Patients who are unable to consent, have cognitive impairments, or have coagulopathy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to compare the outcomes of single port robotic simple prostatectomy using the da Vinci robotic platform with thulium laser enucleation for patients suffering from benign prostatic hyperplasia (BPH). Patients diagnosed with symptomatic BPH who have not responded to conservative treatments will be randomly assigned to one of the two surgical interventions. The study will evaluate primary outcomes such as operative time, blood loss, hospital stay, and postoperative complications, as well as secondary outcomes including quality of life measures. The goal is to provide insights into which surgical method offers better clinical outcomes for patients.
Why it matters
Potential benefit: If successful, this study could help identify the most effective surgical approach for treating BPH, potentially improving patient outcomes and quality of life.
How similar studies have gone: Previous studies have shown comparable outcomes between robotic and laser approaches, but this trial aims to provide prospective data specifically on the single port robotic technique.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients diagnosed with symptomatic Benign Prostatic Hyperplasia (BPH) who fail conservative treatment with drug therapy are eligible for surgical intervention. Exclusion Criteria: * Adults unable to consent Prisoners Cognitive impaired adults Coagulopathy
Where it's running
-
UI Health SCB Clinic Department of Urology
Chicago, Illinois, United States Recruiting
Study contacts
- Principal investigator: Simone Crivellaro, MD — University of Illinois at Chicago, Department of Urology
- Study coordinator: Ruben Sauer, MD
- Email: rsauer1@uic.edu
- Phone: 3124135288
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Evaluating alpha-blocker therapy for managing urinary symptoms after prostate surgery
This study is testing if the medication Tamsulosin can help men feel better by reducing painful and bothersome urinary symptoms after prostate surgery.
-
Adaptive radiotherapy for localized prostate cancer
This study is testing a new type of radiation therapy for men with localized prostate cancer who have urinary problems to see if it can safely treat their cancer without causing too many side effects.
-
Bipolar TURP versus MOSES‑assisted Holmium laser enucleation for enlarged prostate
This trial will test whether MOSES‑assisted Holmium laser enucleation (MoLEP) or bipolar transurethral resection (Bi‑TURP) leads to shorter hospital stays and improved intraoperative outcomes for men with symptomatic benign prostatic hyperplasia and prostate volumes of 40–80 cc.
-
Comparing two treatments for benign prostatic hyperplasia
This study is testing whether a new procedure called Prostate Artery Embolization works better than the traditional surgery for treating enlarged prostate symptoms in men.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.