Comparing robotic and laser surgery for prostate enlargement treatment

Randomized Controlled Trial Comparing Single Port Simple Prostatectomy and Laser Enucleation of the Prostate for Benign Prostatic Hyperplasia

Not applicable Interventional University of Illinois at Chicago · NCT06224218

This study is testing whether robotic surgery or laser surgery is better for treating men with prostate enlargement who haven't found relief from other treatments.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment116 (estimated)
Ages18 Years to 88 Years
SexMale
SponsorUniversity of Illinois at Chicago Academic / other
Locations1 site (Chicago, Illinois)
Trial IDNCT06224218 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to compare the outcomes of single port robotic simple prostatectomy using the da Vinci robotic platform with thulium laser enucleation for patients suffering from benign prostatic hyperplasia (BPH). Patients diagnosed with symptomatic BPH who have not responded to conservative treatments will be randomly assigned to one of the two surgical interventions. The study will evaluate primary outcomes such as operative time, blood loss, hospital stay, and postoperative complications, as well as secondary outcomes including quality of life measures. The goal is to provide insights into which surgical method offers better clinical outcomes for patients.

Who should consider this trial

Good fit: Ideal candidates for this study are adults diagnosed with symptomatic BPH who have failed conservative treatment options.

Not a fit: Patients who are unable to consent, have cognitive impairments, or have coagulopathy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify the most effective surgical approach for treating BPH, potentially improving patient outcomes and quality of life.

How similar studies have performed: Previous studies have shown comparable outcomes between robotic and laser approaches, but this trial aims to provide prospective data specifically on the single port robotic technique.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients diagnosed with symptomatic Benign Prostatic Hyperplasia (BPH) who fail conservative treatment with drug therapy are eligible for surgical intervention.

Exclusion Criteria:

* Adults unable to consent Prisoners Cognitive impaired adults Coagulopathy

Where this trial is running

Chicago, Illinois

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Prostate Hyperplasia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.