Impact of Targeted Physical Activity on Dialysis Patients
Official title: Evaluating the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients.
Run by University of Illinois Chicago · NCT06374537 · Data updated 2026-11-12
This study is testing if a personalized exercise program can help people on dialysis or with severe kidney disease feel better and improve their health over a year.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | University of Illinois Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Status | Recruiting |
| Started | May 22, 2019 |
| Main results expected | April 22, 2027 |
| Study ends | May 2027 |
| Registry record updated | September 8, 2026 |
| Trial ID | NCT06374537 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 and older who are on dialysis or have chronic kidney disease stages 4 or 5 and are considered clinically debilitated.
✕Probably not a fit
Patients with cardiac or pulmonary diseases that contraindicate physical training or those unable to provide consent or travel to the training center may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This research evaluates the effects of a specific physical activity training program, known as the GH Method, on patients undergoing dialysis or suffering from chronic kidney disease stages 4 and 5. The study will enroll 150 clinically debilitated patients who will be randomly assigned to either an intervention group, which will participate in a 12-month personalized exercise rehabilitation program, or a control group with no exercise intervention. Health and functional measures will be assessed at baseline, 6 months, and 12 months to determine the impact of the exercise program. Additionally, a subgroup of patients who are pre- or post-kidney transplant will also be included to assess the intervention's effects in this population.
Why it matters
Potential benefit: If successful, this study could improve the physical health and quality of life for dialysis patients through targeted exercise interventions.
How similar studies have gone: Other studies have shown positive outcomes with exercise interventions in similar patient populations, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinically debilitated patients, currently on dialysis, or have CKD 4 (GFR between 15 and 29), or have CKD 5 (GFR below 15), or post- kidney transplant (for PPKT Subgroup only) as stated by patient's health care professional. * Adequate cognitive ability to complete the questionnaires, give consent for the study and follow the physical and diet instructions Exclusion Criteria: * cardiac/pulmonary disease that contraindicate the physical training * Unable to give consent * Unable to travel to the training center
Where it's running
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University of Illinois at Chicago
Chicago, Illinois, United States Recruiting
Study contacts
- Principal investigator: Enrico Benedetti — University of Illinois Chicago
- Study coordinator: Ilaria Santi
- Email: isanti@uic.edu
- Phone: 312-996-9594
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Italian Registry of Pediatric Dialysis: collecting data from kids on kidney replacement therapy
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.