Remotely Delivered Pilates for MS: Walking, Balance, Fatigue, Mood and Quality of Life
Official title: Does Remotely Delivered Pilates Influence Physical and Psychological Outcomes in Individuals With Multiple Sclerosis?
Run by University of Illinois Chicago · NCT07504120 · Data updated 2026-11-12
A 16-week remote Pilates program will be tested to see if it helps walking, balance, fatigue, pain, mood, thinking, and quality of life for people with multiple sclerosis who can participate from home.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | University of Illinois Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Status | Recruiting |
| Started | November 1, 2025 |
| Main results expected | December 1, 2027 |
| Study ends | December 1, 2027 |
| Registry record updated | October 6, 2026 |
| Trial ID | NCT07504120 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 and older with a clinician-confirmed MS diagnosis, ambulatory without an assistive device, and low to moderate disability.
✕Probably not a fit
Participants with high disability, recent relapse within 30 days, or those unable to access internet/Zoom may see limited or no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study will compare a 16-week remotely delivered Pilates program to a waitlist control in adults with MS. The primary outcomes focus on physical functions such as walking endurance and balance, as well as fatigue and pain. Secondary outcomes examine mood, cognitive function, and overall quality of life. The trial uses online sessions via Zoom and home-based exercises, with testing sessions conducted remotely. Feasibility and efficacy are explored to determine if remote Pilates can be a practical, accessible option for MS management.
Why it matters
Potential benefit: If successful, the program could provide a feasible way for people with MS to improve physical function and well-being from home.
How similar studies have gone: Prior research suggests mind-body and exercise programs can help MS symptoms, but remote Pilates specifically is a relatively novel approach with promising potential.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years or older * Self-reported diagnosis of multiple sclerosis by a neurologist * Relapse-free for the past 30 days before screening * Able to speak and read English as the primary language * Access to the internet and e-mail, * Ability to use Zoom, and willingness to complete testing sessions and questionnaires * Ambulatory without an assistive device (for example, cane) * Low to moderate disability, defined as a score of 0-4 on the Patient-Determined Disease Steps (PDDS) * Insufficiently active, defined as a score \< 14 on the Godin Leisure-Time Exercise Questionnaire-Health Contribution Score (GLTEQ-HCS) * Adequate visual ability and literacy to read materials printed in 14-point font * Currently treated with a disease-modifying therapy Exclusion Criteria: * Pregnant * Elevated risk for strenuous or maximal exercise, defined as more than one "Yes" response on the Physical Activity Readiness Questionnaire (PAR-Q) during screening
Where it's running
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University of Illinois Chicago
Chicago, Illinois, United States Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.