Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Remotely Delivered Pilates for MS: Walking, Balance, Fatigue, Mood and Quality of Life

Official title: Does Remotely Delivered Pilates Influence Physical and Psychological Outcomes in Individuals With Multiple Sclerosis?

Run by University of Illinois Chicago · NCT07504120 · Data updated 2026-11-12

A 16-week remote Pilates program will be tested to see if it helps walking, balance, fatigue, pain, mood, thinking, and quality of life for people with multiple sclerosis who can participate from home.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment50 (estimated)
SponsorUniversity of Illinois Chicago
Academic / other
Locations1 site (Chicago, Illinois)
StatusRecruiting
StartedNovember 1, 2025
Main results expectedDecember 1, 2027
Study endsDecember 1, 2027
Registry record updatedOctober 6, 2026
Trial IDNCT07504120 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 and older with a clinician-confirmed MS diagnosis, ambulatory without an assistive device, and low to moderate disability.

Probably not a fit

Participants with high disability, recent relapse within 30 days, or those unable to access internet/Zoom may see limited or no benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study will compare a 16-week remotely delivered Pilates program to a waitlist control in adults with MS. The primary outcomes focus on physical functions such as walking endurance and balance, as well as fatigue and pain. Secondary outcomes examine mood, cognitive function, and overall quality of life. The trial uses online sessions via Zoom and home-based exercises, with testing sessions conducted remotely. Feasibility and efficacy are explored to determine if remote Pilates can be a practical, accessible option for MS management.

Why it matters

Potential benefit: If successful, the program could provide a feasible way for people with MS to improve physical function and well-being from home.

How similar studies have gone: Prior research suggests mind-body and exercise programs can help MS symptoms, but remote Pilates specifically is a relatively novel approach with promising potential.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 years or older
* Self-reported diagnosis of multiple sclerosis by a neurologist
* Relapse-free for the past 30 days before screening
* Able to speak and read English as the primary language
* Access to the internet and e-mail,
* Ability to use Zoom, and willingness to complete testing sessions and questionnaires
* Ambulatory without an assistive device (for example, cane)
* Low to moderate disability, defined as a score of 0-4 on the Patient-Determined Disease Steps (PDDS)
* Insufficiently active, defined as a score \< 14 on the Godin Leisure-Time Exercise Questionnaire-Health Contribution Score (GLTEQ-HCS)
* Adequate visual ability and literacy to read materials printed in 14-point font
* Currently treated with a disease-modifying therapy

Exclusion Criteria:

* Pregnant
* Elevated risk for strenuous or maximal exercise, defined as more than one "Yes" response on the Physical Activity Readiness Questionnaire (PAR-Q) during screening

Where it's running

  • University of Illinois Chicago
    Chicago, Illinois, United States
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.