Comparing sedation methods for awake fiberoptic intubation
Comparison of Two Sedation Regimens for Awake Fiberoptic Intubation
University of Illinois at Chicago · NCT05736198
This study tests two different sedation methods during awake fiberoptic intubation to see which one helps patients feel more comfortable and stable when they have difficult airways.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 96 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Illinois at Chicago (other) |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT05736198 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the effectiveness of two sedation regimens during awake fiberoptic intubation in patients with potentially difficult airways. Participants will be randomized into two groups: one receiving a combination of midazolam, fentanyl, and a placebo, and the other receiving midazolam, fentanyl, and dexmedetomidine. The study will assess the impact of these sedation protocols on intubation conditions, patient satisfaction, and hemodynamic stability. Data will be collected from patient medical records and through a brief survey conducted 24 hours post-procedure.
Who should consider this trial
Good fit: Ideal candidates are patients with potentially difficult airways requiring awake fiberoptic intubation.
Not a fit: Patients who do not have difficult airways or do not require awake fiberoptic intubation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved sedation practices during awake fiberoptic intubation, enhancing patient safety and comfort.
How similar studies have performed: Other studies have explored sedation methods for intubation, but this specific comparison of dexmedetomidine with standard regimens is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subjects with potentially difficult airways who require awake fiberoptic intubations will be identified from the OR schedule and the pre-operative clinic workups. Exclusion Criteria: * Anyone who does not meet the inclusion criteria
Where this trial is running
Chicago, Illinois
- University of Illinois — Chicago, Illinois, United States (RECRUITING)
Study contacts
- Principal investigator: David Glick, MD — Department of Anesthesiology Head
- Study coordinator: Alexandra Barabanova, MS
- Email: barabano@uic.edu
- Phone: (312)355-5733
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Awake Fiberoptic Intubation, Difficult Airway, Dexmedetomidine