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Clinical trials and research at Centre Hospitalier Universitaire de Nīmes

• 65Clinical trials
• 2Countries

Newest trials

All recruiting trials (65)

• Intraparotid injection of bupivacaine with dexamethasone after partial parotidectomy

  This early-phase study tests whether a single intraparotid injection of bupivacaine with dexamethasone is safe and tolerable after partial parotidectomy for a benign tumor.

  Recruiting Early Phase 1 Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT07812259

• ANTALGEEK Thess Monitoring for outpatient postoperative pain and recovery

  This study tests whether using the ANTALGEEK Thess monitoring device at home, plus a fixed analgesia plan, helps manage acute postoperative pain in adults after outpatient surgery.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard · NCT07680998

• Psilocybin in Alcohol Use Disorder with Depression (Relapse Prevention)

  This study tests whether higher-dose psilocybin-assisted psychotherapy helps prevent relapse in adults with severe alcohol use disorder and depressive symptoms after detox.

  Recruiting Phase 3 Centre Hospitalier Universitaire de Nīmes · Bayonne and 7 other locations · NCT07638553

• 12-month effects of keeping the posterior cruciate ligament during MAKO robotic-assisted total knee replacement

  This trial tests whether keeping the posterior cruciate ligament during MAKO robotic-assisted total knee replacement leads to better function at 12 months for people having a first-time unilateral knee replacement.

  Recruiting at 3 sites Centre Hospitalier Universitaire de Nīmes · Bordeaux and 2 other locations · NCT07489963

• How atypical work schedules and idle time at work affect at-risk gambling

  See if unusual work hours and having idle time at work are linked to at-risk gambling in working adults who score 5 or higher on the Problem Gambling Severity Index.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nantes and 1 other locations · NCT07421765

• Does spinal manipulation help with acute and subacute lower back pain?

  For adults with recent low back pain, this study tests whether spinal manipulation can provide short-term relief and improved function.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard · NCT07403500

• Combined mPCR and algorithm-based therapy to optimize early antibiotics in VAP

  This trial tests whether adding a broad respiratory mPCR test and a local-epidemiology algorithm helps doctors choose better initial antibiotics within 24 hours for adults with ventilator-associated pneumonia.

  Recruiting at 2 sites Phase 4 Centre Hospitalier Universitaire de Nīmes · Alès and 1 other locations · NCT07403474

• MinION sequencing to identify microbes in diabetic foot bone infections

  This study will test a rapid MinION DNA sequencing method to identify bacteria, fungi, and resistance genes in infected diabetic foot wounds and compare the results with standard culture.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard · NCT07391995

• Radiomic MRI model to predict response to chemoradiotherapy in locally advanced cervical cancer

  This project tests whether MRI-based radiomic features can predict how women with locally advanced cervical cancer will respond to combined chemotherapy and radiation.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard · NCT07305727

• Monthly blood monitoring of neurofilament light to detect hidden activity in treated relapsing-remitting MS

  This will test whether monthly blood measurements of neurofilament light (pNfL) can find hidden disease activity in people with treated relapsing-remitting MS.

  Recruiting at 4 sites Centre Hospitalier Universitaire de Nīmes · Montpellier and 5 other locations · NCT07292480

• Transition pathway to support cancer patients after hospital discharge

  This project will try the OncoCare transition program, using patient-reported symptom check-ins and follow-up calls to help adults with cancer after they leave the hospital.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT07256444

• Iron-chelator added to dialysis fluid in sepsis-related AKI on CRRT

  In adults with sepsis-associated acute kidney injury requiring dialysis, this study tests whether adding the iron-binding drug MEX-CD1 to dialysis fluid helps remove more iron compared with standard dialysis fluid.

  Recruiting Phase 1/2 Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard and 1 other locations · NCT07236463

• See how common Muir-Torre syndrome is among people with Lynch syndrome

  This study tests how common Muir-Torre syndrome is in people with a confirmed Lynch syndrome.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard · NCT07201012

• ECCCLORE group program for people with addiction and trauma-related PTSD

  This program will try a group-based ECCCLORE therapy to see if it helps people who have addiction and PTSD or complex PTSD reduce substance use and impulsive or hostile behaviors.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Nîmes · NCT07193914

• Lipoprotein(a) and cardiovascular risk in stage 4 CKD patients not on dialysis

  This observational study tests whether high lipoprotein(a) levels are linked to heart and blood vessel problems in people with stage 4 chronic kidney disease who are not yet on dialysis.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT07141628

• Resistance exercise with blood flow restriction for heart failure with reduced ejection fraction

  This trial tests whether adding blood flow restriction to light-to-moderate resistance training can improve heart and muscle function in people with heart failure and reduced ejection fraction.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard · NCT07118410

• Which factors predict success of rehab for chronic low back pain?

  This project will test whether physical tests, psychosocial measures, and biomarkers can predict who with chronic low back pain will benefit from a mobility skills rehabilitation session.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Clermont-Ferrand, Auvergne and 5 other locations · NCT07051772

• Midbrain hearing centers and hearing voices in schizophrenia

  This project tries to see if changes in the inferior colliculi (a midbrain auditory center) are linked to recent auditory hallucinations in people with schizophrenia using unenhanced brain MRI.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT07003529

• Monitoring beta-lactam antibiotics and kidney clearance in ICU patients with acute brain injury

  This project tries to see if checking kidney clearance together with blood drug levels can quickly identify ICU patients with acute brain injury who need higher doses of beta-lactam antibiotics.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT06999161

• Tablet-based music vs oxygen–nitrous oxide gas to reduce anxiety during CT-guided lumbar injections

  This test tries to see if a tablet music program can calm adults with low back pain and anxiety during CT-guided lumbar injections as well as the usual oxygen–nitrous oxide gas (EMONO).

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT06928740

• Point-of-care fingertip CRP testing to guide care for febrile children

  We will test a small fingertip (capillary) C‑reactive protein (CRP) test in primary care to help doctors decide care for children with fever who need a CRP measurement.

  Recruiting at 37 sites Centre Hospitalier Universitaire de Nīmes · Agde and 36 other locations · NCT06910631

• Measuring L-PGDS levels in blood, urine, vaginal fluid and endometrial tissue

  This project will test whether L-PGDS levels in blood, urine, vaginal fluid and uterine tissue differ between women with adenomyosis, other benign uterine conditions, and healthy controls.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT06864494

• Ileocolic resection with extended mesenteric removal for Crohn's disease

  This trial will try removing more of the mesentery during ileocolic surgery in people with Crohn's disease who are on biologic medicines to see if it is safe and reduces early endoscopic recurrence.

  Recruiting at 2 sites Centre Hospitalier Universitaire de Nīmes · Montpellier and 1 other locations · NCT06856044

• Comparing niraparib and bevacizumab for ovarian cancer maintenance therapy

  This study is trying to see if a maintenance treatment with niraparib works better than bevacizumab for women with advanced ovarian cancer who have already had chemotherapy.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Occitanie · NCT06827353

• MRI signs of acute brain hemorrhage in microangiopathy patients

  Aiming to see if gadolinium-enhanced MRI can reveal markers of hematoma progression in people with acute lobar brain bleeds due to microangiopathy.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard · NCT06781034

• Autophagy and cell-death balance in placenta-related pregnancy complications

  This observational project will test whether changes in autophagy and apoptosis in the placenta are linked to pre-eclampsia or intrauterine growth restriction in pregnant women delivering at Nîmes University Hospital.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT06779916

• Testing a new method to predict response to immunotherapy in bladder cancer patients

  This study is testing a new test called SPHERTEST to see if it can help doctors figure out which bladder cancer patients are likely to respond well to immunotherapy after chemotherapy.

  Recruiting at 2 sites Centre Hospitalier Universitaire de Nīmes · Montpellier and 4 other locations · NCT06738797

• Sleep inertia in major depressive disorder measured with the psychomotor vigilance task

  This study will test whether overnight sleep recordings and a simple vigilance task can reveal sleep inertia in people with major depression compared with depressed people without sleep inertia and with non-depressed controls.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT06732284

• Exploring the Connection Between Muscle and Bone in Healthy Women

  This study is trying to see how muscle affects bone health in healthy women aged 20 to 89 by looking at muscle strength and bone density.

  Recruiting at 2 sites Centre Hospitalier Universitaire de Nīmes · Montpellier and 1 other locations · NCT06683222

• Comparing two techniques for treating coagulation disorders caused by plasmapheresis

  This study is testing two different plasmapheresis techniques to see how they affect blood clotting in adults who need ongoing treatment for coagulation disorders.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, France · NCT06571552

• Improving balance in amputees using virtual reality versus traditional rehab

  This study tests whether using virtual reality for rehab can help people with one leg amputated below the knee improve their balance better than traditional rehab methods.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Le Grau-du-Roi and 1 other locations · NCT06424249

• Effects of a Walking Test on Blood Clotting in Patients

  This study tests how a 60-minute walking test affects blood clotting in people with and without a history of blood clots.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Occitanie · NCT06418633

• Understanding what limits walking for people with a leg amputation

  This observational study in adults with lower limb amputation tests how various factors affect their ability to walk and rehab progress.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard · NCT06415955

• Comparing two dialysis techniques for kidney injury in ICU patients

  This study is testing whether a new dialysis method using citrate is just as good as a traditional method using heparin for helping ICU patients with kidney injury lower their urea levels.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT06369064

• Gut bacteria and bacterial translocation in people with type 1 narcolepsy versus controls

  This study will test whether the gut microbiome and bacterial translocation differ in people with type 1 narcolepsy compared with people without hypersomnolence problems.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard and 1 other locations · NCT06292598

• Embolization of the Inferior Mesenteric Artery before Rectal Surgery

  This study tests if blocking a specific artery before rectal surgery can help people with tumors recover better and have fewer complications.

  Recruiting at 3 sites Centre Hospitalier Universitaire de Nīmes · Montpellier and 2 other locations · NCT06236633

• Using music therapy to help patients with lower limb artery disease

  This study tests whether a music therapy walking program can help people with lower limb artery disease walk better and improve their overall health.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT06226844

• Early transfer of culture medium before embryo transfer

  This study is testing if putting a special fluid in the uterus before transferring frozen embryos can help women who have had trouble getting pregnant in the past.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Clamart and 6 other locations · NCT06177613

• IAP Overexpression and Cervical Cancer Recurrence in Radio-Chemotherapy Patients

  This study checks whether higher levels of inhibitors of apoptosis proteins (IAPs) in cervical cancer patients treated with radio-chemotherapy can predict cancer coming back within 2 years.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard · NCT06147960

• Testing a new method to detect COVID-19 using exhaled air

  This study is testing a new breath test for COVID-19 to see if it works as well as the traditional nose swab method, especially for people showing symptoms or who have been around someone infected.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes and 1 other locations · NCT06099795

• Targeted RNA sequencing for diagnosing ALS

  This study is testing a new way to use RNA sequencing to help diagnose ALS more accurately by looking for specific genetic changes in people who have been prescribed genetic testing for the disease.

  Recruiting at 7 sites Centre Hospitalier Universitaire de Nīmes · Bordeaux and 6 other locations · NCT06083584

• Evaluating the effects of dexmedetomidine in outpatient surgery anesthesia

  This study is testing if using dexmedetomidine instead of opioids during outpatient surgeries can help patients feel better and wake up more smoothly after anesthesia.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT06082856

• Echocardiographic changes in elderly patients after blood transfusion

  This study is testing how blood transfusions affect heart function in elderly patients by checking their heart images before and after the transfusion.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard · NCT06060639

• Multidisciplinary care for elderly patients undergoing colorectal surgery

  This study tests whether a special team approach to care can help older patients recover better after colorectal cancer surgery.

  Recruiting at 3 sites Centre Hospitalier Universitaire de Nīmes · Nîmes, France and 3 other locations · NCT05993923

• Short therapy program for young adults with borderline personality disorder

  This study is testing a new 10-week therapy program for young adults with borderline personality disorder to see if it can help reduce impulsive behaviors and improve their overall well-being.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT05913544

• Comparing routine and symptom-based PPI therapy after a procedure for esophageal achalasia

  This study is testing whether giving patients with esophageal achalasia a routine 12-month prescription for heartburn medication after a specific procedure can help prevent throat inflammation better than only giving the medication when they have symptoms.

  Recruiting at 4 sites Centre Hospitalier Universitaire de Nīmes · Marseille and 3 other locations · NCT05899842

• Evaluating fluid responsiveness in shock patients using tissue Doppler

  This study is testing if measuring heart movement with ultrasound can help doctors tell if patients in shock will benefit from receiving extra fluids.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT05888974

• Evaluation of the Anchorsure® Device for Treating Apical Prolapse in Women

  This study is testing a new device called Anchorsure® to see if it can help women with pelvic organ prolapse have a quicker and less painful surgery while keeping everything securely in place.

  Recruiting at 4 sites Centre Hospitalier Universitaire de Nīmes · La Rochelle and 3 other locations · NCT05836844

• Impact of changing PICCline dressings on infection rates in leukemia patients

  This study is testing if changing the dressings on PICC lines more often can help reduce infection rates in leukemia patients receiving chemotherapy.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Montpellier · NCT05793801

• Assessing cerebral blood flow response using a new index

  This study is testing a new way to measure blood flow in the brain to see if it can help identify patients with narrowed or blocked carotid arteries who might need surgery.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT05780619

• Understanding pelvic and spinal positioning in sitting children with cerebral palsy

  This study looks at how children with cerebral palsy sit and how their pelvis and spine are positioned to help improve their care and prevent problems.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT05657548

• Evaluating quality of life in diabetic patients with chronic Charcot foot

  This study looks at how living with chronic Charcot foot affects the quality of life for people with diabetes over two years to see what factors might lead to worse outcomes.

  Recruiting at 8 sites Centre Hospitalier Universitaire de Nīmes · Boulogne-sur-Mer, Pas-de-Calais and 16 other locations · NCT05491577

• Examining gut microbiota diversity in young children on long-term antibiotic prophylaxis for urinary reflux

  This study looks at how long-term antibiotic use affects the gut bacteria in young children with urinary reflux compared to other children who don't take antibiotics.

  Recruiting at 2 sites Centre Hospitalier Universitaire de Nīmes · Montpellier and 1 other locations · NCT05319067

• Impact of lumbar surgery on walking complexity in chronic low back pain patients

  This study is testing how lumbar surgery affects the walking ability of people with chronic low back pain to see if it helps them move better after the operation.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes and 1 other locations · NCT05231265

• Impact of case manager intervention on psychotic episode recurrence in young adults

  This study tests whether having a trained case manager can help young adults aged 16 to 30 who have had their first psychotic episode avoid having more episodes.

  Recruiting at 3 sites Centre Hospitalier Universitaire de Nīmes · Toulouse, Choisir Une Région and 5 other locations · NCT05116514

• How obesity treatment patients at Nîmes Hospital may show misuse of alcohol and other addictions

  This study looks to see if adults being treated for obesity at Nîmes University Hospital develop alcohol or other addictions over time.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT04613791

• Comparing mindfulness and relaxation techniques for treating alcohol use disorder

  This study is testing whether a mindfulness program can help people with alcohol use disorder stay sober better than a simple relaxation technique.

  Recruiting at 3 sites Centre Hospitalier Universitaire de Nīmes · Angers and 6 other locations · NCT04598399

• Exploring how treatment affects gut bacteria in young patients with spondylarthropathy

  This study is trying to see how different treatments for juvenile spondylarthropathy affect gut bacteria in kids aged 8 to 17.

  Recruiting at 3 sites Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard and 3 other locations · NCT04540432

• Heart rate variability as a marker for complications after colorectal surgery

  This study tests whether heart rate variability can signal potential complications after colorectal surgery in adults with cancer or inflammatory bowel disease.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes · NCT04367987

• Dorso-lateral Prefrontal Cortex Stimulation for Motor Conversion Disorder

  This study is testing if a new type of brain stimulation can help people with motor conversion disorder improve their movement and regain control over their symptoms.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Nîmes, Gard and 7 other locations · NCT04097184

• Improving medication management for elderly surgical patients

  This study tests whether having a pharmacist and a doctor work together can help older surgical patients manage their medications more safely and effectively.

  Recruiting at 3 sites Centre Hospitalier Universitaire de Nīmes · Grenoble and 3 other locations · NCT03827031

• Using buprenorphine to reduce severe suicidal thoughts in depressed patients

  This study is testing if low doses of buprenorphine can help reduce severe suicidal thoughts in people experiencing major depression.

  Recruiting at 7 sites Phase 3 Centre Hospitalier Universitaire de Nīmes · Bordeaux, France and 8 other locations · NCT03646058

• Validation of a French version of a compliance questionnaire for rheumatology

  This study is testing a French version of a questionnaire to see how well it helps patients with rheumatoid arthritis understand and follow their methotrexate treatment.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Bordeaux and 3 other locations · NCT03642795

• Estimating the prevalence of advanced chronic kidney disease in Gard, France

  This study is trying to see how common advanced chronic kidney disease is in Gard, France, by comparing lab data with patient records to better understand how care is provided.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Alès and 3 other locations · NCT02938611

• Low-dose whole-body angiography for imaging after stroke or TIA

  This study is testing whether using a low-dose whole-body angiography can help people who have had a stroke or TIA get diagnosed faster and more accurately compared to standard imaging methods.

  Recruiting Centre Hospitalier Universitaire de Nīmes · Montpellier and 1 other locations · NCT02662751

Quick answers

How many clinical trials run by Centre Hospitalier Universitaire de Nīmes are recruiting right now?

65, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in France (65 trials), Reunion (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Early Phase 1: 1, Phase 4: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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