Low-dose whole-body angiography for imaging after stroke or TIA

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare two imaging strategies for patients who have experienced a stroke or transient ischemic attack (TIA). One strategy follows the usual imaging protocols at participating centers, while the other begins with a low-dose whole-body angiography. The study will evaluate the number of clinically significant lesions detected, time to diagnosis, hospitalization duration, and overall diagnostic efficiency. Additionally, it will assess the impact on quality of life and the incidence of new cardiovascular events over a follow-up period of 36 months.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The patient was informed about the implementation of the study, its objectives, constraints and patient rights
* The patient has given free and informed consent and signed the consent
* Patient affiliated with or beneficiary of a health insurance plan
* Patient available for 36 months of follow-up
* The patient has had a stroke (within the past 10 days, diagnosis confirmed by MRI with a diffusion sequence) or transient ischemic attack (within the past 10 days, ABCD2 score greater than 3) without haemorrhage

Exclusion Criteria:

* The patient is currently participating in or has participated in another biomedical research study within the past three months or is currently in an exclusion period determined by a previous study.
* Patient under guardianship or judicial protection
* Refusal to sign the consent
* Inability to correctly inform the patient or his/her trusted person about the study
* The patient is pregnant, parturient, or breastfeeding
* The patient has a contraindication for a treatment used in this study
* Known allergy to contrast medium or severe allergy to iodine
* Known active malignancy or history of cancer treatment
* The patient has already undergone a full body scanner in the previous three months
* Renal failure with creatinine clearance below 60 ml / min
* Monoclonal immunoglobulin
* History of severe symptomatic cardiovascular event (myocardial infarction, aortic dissection, mesenteric ischemia, renal ischemia)
* Emergency situations that hamper the planned course of the study

Where it's running

• CHRU de Montpellier - Hôpital Gui de Chauliac
  Montpellier, France Recruiting
• CHRU de Nîmes - Hôpital Universitaire Carémeau
  Nîmes, France Not yet recruiting

Study contacts

• Study coordinator: Francesco Macri, MD
• Email: francesco.macri@chu-nimes.fr
• Phone: +33.(0)6.19.42.18.52

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Deep phenotyping to explore recovery in young adults after stroke

  This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.

  Recruiting The Florey Institute of Neuroscience and Mental Health · Heidelberg, Victoria and 1 other locations · NCT07019493

• Stem cell therapy for chronic stroke recovery

  This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.

  Recruiting Phase 2 Hokkaido University Hospital · Sapporo, Hokkaido · NCT06752720

• AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals

  This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.

  Recruiting at 2 sites Hospital Universitari Vall d'Hebron Research Institute · Leuven and 6 other locations · NCT07924371

• Web-based therapy using action observation and mirror therapy for arm weakness after stroke

  This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.

  Recruiting Chang Gung Memorial Hospital · Taoyuan · NCT07921108

• Remote Ischaemic Conditioning for Fatigue After Stroke 2

  Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.

  Recruiting Phase 2 Sheffield Teaching Hospitals NHS Foundation Trust · Sheffield, South Yorkshire · NCT07914647

• Dual-task balance training plus computer-based cognitive training after stroke

  In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.

  Recruiting Matia Foundation · San Sebastián, GUIPUZCOA · NCT07913620

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.