Heart rate variability as a marker for complications after colorectal surgery
Official title: Variability of Heart Rate as a Marker of Complication of Colorectal Surgery
Run by Centre Hospitalier Universitaire de Nīmes · NCT04367987 · Data updated 2026-11-12
This study tests whether heart rate variability can signal potential complications after colorectal surgery in adults with cancer or inflammatory bowel disease.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 117 (estimated) |
| Sponsor | Centre Hospitalier Universitaire de Nīmes Academic / other |
| Locations | 1 site (Nîmes) |
| Status | Recruiting |
| Started | June 17, 2020 |
| Main results expected | June 2027 |
| Study ends | June 2027 |
| Registry record updated | June 16, 2026 |
| Trial ID | NCT04367987 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults undergoing scheduled colorectal resection for cancer, diverticulitis, or chronic inflammatory bowel disease, with ASA 1–2 and who have consented to participate and hold health insurance membership.
✕Probably not a fit
Patients with certain medications, specific heart or nerve problems, or those in interventional or guardianship scenarios may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study examines how postoperative changes in heart rate variability relate to complications following colorectal surgery. It includes adults with scheduled colorectal resections who are healthy enough for surgery and have consented to participate. Heart rate variability is recorded to explore its association with adverse postoperative events. The study is conducted at CHU de Nîmes with inclusion and exclusion criteria to select appropriate surgical patients without confounding conditions or medications.
Why it matters
Potential benefit: If successful, heart rate variability could help identify patients at higher risk of complications after colorectal surgery.
How similar studies have gone: Previous research has investigated heart rate variability as a marker in surgical and critical care settings, suggesting potential relevance for predicting complications, though evidence specificity to colorectal surgery varies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients operated for a scheduled colorectal resection due to cancer, diverticulitis, or Chronic Inflammatory Bowel Disease, * American Society of Anesthesiologists score 1-2 * The patient must have given their free and informed consent and signed the consent form * The patient must be a member or beneficiary of a health insurance plan Exclusion Criteria: * Patient taking antidepressants, antipsychotics, antihypertensive beta blocker type, anti-arythmic or oral contraception * Uncontrolled diabetes or associated with a neuropathy * Arrhythmias and conduction disturbances, , coronaropathy and heart failure, kidney failure * Neuropathies * Pacemaker or defibrillator * The subject is participating in another interventional study, or is in a period of exclusion determined by a previous study * The subject refuses to sign the consent * It is impossible to give the subject informed information * The patient is under safeguard of justice or state guardianship
Where it's running
-
CHU de Nimes
Nîmes, France Recruiting
Study contacts
- Principal investigator: Martin Bertrand — CHU Nimes
- Study coordinator: Martin Bertrand
- Email: martin.bertrand@chu-nimes.fr
- Phone: 04.66.68.68.09
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.