Comparing mindfulness and relaxation techniques for treating alcohol use disorder
Comparison of the Effectiveness of Two Psycho-physical Interventions: Mindfulness Based Relapse Prevention (MBRP) and Unguided Meditative Relaxation in Patients With Alcohol Use Disorder
This study is testing whether a mindfulness program can help people with alcohol use disorder stay sober better than a simple relaxation technique.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 168 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire de Nīmes Academic / other |
| Locations | 7 sites (Angers and 6 other locations) |
| Trial ID | NCT04598399 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of two psycho-physical interventions, Mindfulness Based Relapse Prevention (MBRP) and unguided meditative relaxation, in patients with alcohol use disorder (AUD). The researchers aim to determine whether MBRP is more effective than a relaxation program in preventing relapse among individuals who have recently reduced their alcohol consumption. Participants must meet specific criteria related to their alcohol use and mental health status to be eligible for the study. The study is conducted at multiple locations in France, focusing on patients who have experienced moderate to severe AUD.
Who should consider this trial
Good fit: Ideal candidates are individuals with moderate to severe alcohol use disorder who have not consumed alcohol in the last 60 days.
Not a fit: Patients with severe depression, schizophrenia, or significant cognitive impairments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a new, effective non-pharmacological treatment option for patients struggling with alcohol use disorder.
How similar studies have performed: Other studies have shown promising results for mindfulness-based interventions in addiction treatment, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Having a moderate to severe alcohol use disorder according to DSM 5 criteria. * The last drink must have been consumed at most in the last 60 days before the pre-inclusion visit. The patient must have had at least 1 HDD during the last drinking period Exclusion Criteria: * Severe depression (Beck Depression Inventory\> 30) * Schizophrenic disorder, * Current maniac or hypomaniac episode, * Patient with dementia or severe cognitive impairment that would prevent him/her from following the course of a session, as judged by the clinician. * Insufficient French understanding to complete the questionnaires * Pregnant or breastfeeding woman * Absence of social security regimen * Other mindfulness-based structured therapies * Refusal to sign the written consent. • The patient is under safeguard of justice or state guardianship
Where this trial is running
Angers and 6 other locations
- Ssra Les Eumenides — Angers, France (Recruiting)
- Hôpital Corentin-Celton — Issy-les-Moulineaux, France (Not_yet_recruiting)
- CHU de Nantes — Nantes, France (Recruiting)
- CHU de Nimes — Nîmes, France (Recruiting)
- Hopital Fernand Widal — Paris, France (Not_yet_recruiting)
- Hopital Des 4 Villes — Sèvres, France (Not_yet_recruiting)
- Hopital Paul Brousse — Villejuif, France (Not_yet_recruiting)
Study contacts
- Principal investigator: Amandine Luquiens — CHU Nimes
- Study coordinator: Amandine Luquiens
- Email: Amandine.luquiens@chu-nimes.fr
- Phone: 04.66.68.69.98
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.