Which factors predict success of rehab for chronic low back pain?
Predictive Factors for the Success of Rehabilitation Programs in Chronic Low Back Pain
This project will test whether physical tests, psychosocial measures, and biomarkers can predict who with chronic low back pain will benefit from a mobility skills rehabilitation session.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 333 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire de Nīmes Academic / other |
| Locations | 6 sites (Clermont-Ferrand, Auvergne and 5 other locations) |
| Trial ID | NCT07051772 on ClinicalTrials.gov |
What this trial studies
This observational project will collect physical mobility test results, psychosocial questionnaires, and biomarker information from adults with chronic low back pain who consent to participate. Participants will attend a mobility skills testing session and their baseline characteristics will be linked to measures of rehabilitation outcome. The team will analyze which combinations of factors best predict improvement or persistent limitations. Recruitment takes place at university hospitals in Clermont-Ferrand, Nîmes, and Montpellier in France.
Who should consider this trial
Good fit: Adults with chronic low back pain lasting three months or more who can give informed consent and are members or beneficiaries of a health insurance plan are ideal candidates.
Not a fit: People currently enrolled in a category 1 interventional drug or device trial, under legal guardianship, pregnant or breastfeeding, or being treated for psychiatric, cancerous, or orthopedic conditions that alter care are unlikely to benefit from this protocol.
Why it matters
Potential benefit: If successful, this could help match patients to rehabilitation approaches they are more likely to benefit from, avoid ineffective treatments, and speed recovery.
How similar studies have performed: Previous work has shown psychosocial and physical measures can predict rehab outcomes (for example tools like STarT Back), but biomarker-based prediction in this context is less established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient with chronic low back pain ≥ three months * The patient must have given their free and informed consent and signed the consent form * The patient must be a member or beneficiary of a health insurance plan Exclusion Criteria: * The patient is participating in a category 1 interventional study, or a study on a medication or medical device without prior approval of the primary investigator * The patient is in a period of exclusion determined by a previous study * It is impossible to give the subject informed information * The patient is under safeguard of justice or state guardianship * Patient followed or treated for a psychiatric, cancerous or orthopedic pathology that risks modifying their course of care * Pregnant, parturient or breastfeeding patient.
Where this trial is running
Clermont-Ferrand, Auvergne and 5 other locations
- CHU de Clermont Ferrand — Clermont-Ferrand, Auvergne, France (Not_yet_recruiting)
- Centre Hospitalier Universitaire de Nîmes — Nîmes, Gard, France (Not_yet_recruiting)
- CHU de Montpellier — Montpellier, Occitanie, France (Not_yet_recruiting)
- CHU de Nîmes — Nîmes, Occitanie, France (Recruiting)
- CHU de Clermont-Ferrand — Clermont-Ferrand, France (Not_yet_recruiting)
- CHU de Montpellier — Montpellier, France (Not_yet_recruiting)
Study contacts
- Principal investigator: Arnaud Dupeyron — CHU de Nimes
- Study coordinator: Arnaud Dupeyron
- Email: arnaud.dupeyron@chu-nimes.fr
- Phone: 04.66.68.34.59
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.