Which factors predict success of rehab for chronic low back pain?
Official title: Predictive Factors for the Success of Rehabilitation Programs in Chronic Low Back Pain
Run by Centre Hospitalier Universitaire de Nīmes · NCT07051772 · Data updated 2026-11-12
This project will test whether physical tests, psychosocial measures, and biomarkers can predict who with chronic low back pain will benefit from a mobility skills rehabilitation session.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 333 (estimated) |
| Sponsor | Centre Hospitalier Universitaire de Nīmes Academic / other |
| Locations | 6 sites (Clermont-Ferrand, Auvergne and 5 other locations) |
| Status | Recruiting |
| Started | February 19, 2025 |
| Main results expected | February 2028 |
| Study ends | August 2028 |
| Registry record updated | January 16, 2026 |
| Trial ID | NCT07051772 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with chronic low back pain lasting three months or more who can give informed consent and are members or beneficiaries of a health insurance plan are ideal candidates.
✕Probably not a fit
People currently enrolled in a category 1 interventional drug or device trial, under legal guardianship, pregnant or breastfeeding, or being treated for psychiatric, cancerous, or orthopedic conditions that alter care are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational project will collect physical mobility test results, psychosocial questionnaires, and biomarker information from adults with chronic low back pain who consent to participate. Participants will attend a mobility skills testing session and their baseline characteristics will be linked to measures of rehabilitation outcome. The team will analyze which combinations of factors best predict improvement or persistent limitations. Recruitment takes place at university hospitals in Clermont-Ferrand, Nîmes, and Montpellier in France.
Why it matters
Potential benefit: If successful, this could help match patients to rehabilitation approaches they are more likely to benefit from, avoid ineffective treatments, and speed recovery.
How similar studies have gone: Previous work has shown psychosocial and physical measures can predict rehab outcomes (for example tools like STarT Back), but biomarker-based prediction in this context is less established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient with chronic low back pain ≥ three months * The patient must have given their free and informed consent and signed the consent form * The patient must be a member or beneficiary of a health insurance plan Exclusion Criteria: * The patient is participating in a category 1 interventional study, or a study on a medication or medical device without prior approval of the primary investigator * The patient is in a period of exclusion determined by a previous study * It is impossible to give the subject informed information * The patient is under safeguard of justice or state guardianship * Patient followed or treated for a psychiatric, cancerous or orthopedic pathology that risks modifying their course of care * Pregnant, parturient or breastfeeding patient.
Where it's running
-
CHU de Nîmes
Nîmes, Occitanie, France Recruiting -
CHU de Clermont Ferrand
Clermont-Ferrand, Auvergne, France Not yet recruiting -
Centre Hospitalier Universitaire de Nîmes
Nîmes, Gard, France Not yet recruiting -
CHU de Montpellier
Montpellier, Occitanie, France Not yet recruiting -
CHU de Clermont-Ferrand
Clermont-Ferrand, France Not yet recruiting -
CHU de Montpellier
Montpellier, France Not yet recruiting
Study contacts
- Principal investigator: Arnaud Dupeyron — CHU de Nimes
- Study coordinator: Arnaud Dupeyron
- Email: arnaud.dupeyron@chu-nimes.fr
- Phone: 04.66.68.34.59
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.