Testing a new method to detect COVID-19 using exhaled air

Evaluation of Concordance Between an Innovative Test on Exhaled Air (eBAM-CoV) and RT-PCR to Detect SARS-CoV-2 in Symptomatic Patients or Closed Contacts

Not applicable Interventional Centre Hospitalier Universitaire de Nīmes · NCT06099795

This study is testing a new breath test for COVID-19 to see if it works as well as the traditional nose swab method, especially for people showing symptoms or who have been around someone infected.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment250 (estimated)
Ages18 Years and up
SexAll
SponsorCentre Hospitalier Universitaire de Nīmes Academic / other
Locations2 sites (Marseille and 1 other locations)
Trial IDNCT06099795 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of the eBAM-CoV test, which detects SARS-CoV-2 viral proteins in exhaled air, compared to the traditional RT-PCR method that uses nasopharyngeal swabs. The eBAM-CoV test aims to provide a less invasive and more immediate assessment of viral load, particularly in symptomatic patients or those who have been in close contact with infected individuals. Researchers will analyze the concordance between the two testing methods to determine the reliability of the eBAM-CoV test for COVID-19 diagnosis.

Who should consider this trial

Good fit: Ideal candidates include adults over 18 years old who are suspected of having COVID-19, either due to symptoms or close contact with an infected person.

Not a fit: Patients who are unable to understand the testing procedures or are currently participating in another interventional study may not benefit from this study.

Why it matters

Potential benefit: If successful, this test could offer a quicker and less invasive way to diagnose COVID-19, improving patient care and response times.

How similar studies have performed: While traditional RT-PCR testing has been widely used, the eBAM-CoV test represents a novel approach that has not been extensively tested in similar studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult male or female patients over 18 years of age (≥)
* Suspected of being infected with COVID-19 (symptomatic or contact case) and consulting for RT-PCR screening.

Exclusion Criteria:

* Inability to understand the procedures to use the device
* Patient participating in an another interventional study
* Patient in exclusion period determined by another study
* Patient under court protection or guardianship
* Patient/trusted person/legal representative/family member for whom it is impossible to give informed information.
* Pregnant, parturient or breast-feeding patient

Where this trial is running

Marseille and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions SARS-CoV-2 InfectionCOVID-19CoronavirusDiagnostic Test Kits
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.