MRI signs of acute brain hemorrhage in microangiopathy patients
Official title: Descriptive Study on MRI Contrast of Acute Cerebral Hemorrhage in Different Microangiopathies
Run by Centre Hospitalier Universitaire de Nīmes · NCT06781034 · Data updated 2026-11-12
Aiming to see if gadolinium-enhanced MRI can reveal markers of hematoma progression in people with acute lobar brain bleeds due to microangiopathy.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 128 (estimated) |
| Sponsor | Centre Hospitalier Universitaire de Nīmes Academic / other |
| Locations | 1 site (Nîmes, Gard) |
| Status | Recruiting |
| Started | February 3, 2025 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | July 1, 2026 |
| Trial ID | NCT06781034 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Patients with acute cerebral hematomas from databases of cerebral amyloid angiopathy or hypertensive microangiopathy who had follow-up CT scans.
✕Probably not a fit
Patients without follow-up imaging or with imaging findings not associated with progression may not derive immediate benefit from these results.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study reviews how gadolinium-enhanced MRI—looking for ‘spot signs’—appears during the acute phase of lobar cerebral hemorrhages. It uses existing patient data from Nîmes University Hospital to link MRI findings with subsequent imaging changes. No interventions are performed; researchers focus on imaging patterns and their potential to identify higher-risk subgroups. The goal is to lay groundwork for selecting patients who might benefit from future targeted therapies. Findings could improve understanding of hemorrhage evolution and help inform future trials.
Why it matters
Potential benefit: If successful, the study could help identify patients at higher risk of hematoma growth using MRI markers.
How similar studies have gone: Similar MRI-based markers have been described in the CT literature, and MRI-based markers are being explored but remain investigational.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with acute cerebral hematomas from existing databases of cerebral amyloid angiopathy and hypertensive microangiopathy managed at Nîmes University Hospital; * Patients who have undergone a follow-up cerebral CT scan in the event of worsening or for follow-up. Exclusion Criteria: * Patient refusing to participate
Where it's running
-
CHU de Nîmes
Nîmes, Gard, France Recruiting
Study contacts
- Study coordinator: Teodora PARVU
- Email: teodora.parvu@chu-nimes.fr
- Phone: 04.66.68.32.61
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.