Clinical trial Recruiting at 1 site Observational Ages 18 and up

MRI signs of acute brain hemorrhage in microangiopathy patients

Official title: Descriptive Study on MRI Contrast of Acute Cerebral Hemorrhage in Different Microangiopathies

Run by Centre Hospitalier Universitaire de Nīmes · NCT06781034 · Data updated 2026-11-12

Aiming to see if gadolinium-enhanced MRI can reveal markers of hematoma progression in people with acute lobar brain bleeds due to microangiopathy.

More Cerebral Hemorrhage trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment128 (estimated)
SponsorCentre Hospitalier Universitaire de Nīmes
Academic / other
Locations1 site (Nîmes, Gard)
StatusRecruiting
StartedFebruary 3, 2025
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedJuly 1, 2026
Trial IDNCT06781034 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Patients with acute cerebral hematomas from databases of cerebral amyloid angiopathy or hypertensive microangiopathy who had follow-up CT scans.

Probably not a fit

Patients without follow-up imaging or with imaging findings not associated with progression may not derive immediate benefit from these results.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study reviews how gadolinium-enhanced MRI—looking for ‘spot signs’—appears during the acute phase of lobar cerebral hemorrhages. It uses existing patient data from Nîmes University Hospital to link MRI findings with subsequent imaging changes. No interventions are performed; researchers focus on imaging patterns and their potential to identify higher-risk subgroups. The goal is to lay groundwork for selecting patients who might benefit from future targeted therapies. Findings could improve understanding of hemorrhage evolution and help inform future trials.

Why it matters

Potential benefit: If successful, the study could help identify patients at higher risk of hematoma growth using MRI markers.

How similar studies have gone: Similar MRI-based markers have been described in the CT literature, and MRI-based markers are being explored but remain investigational.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with acute cerebral hematomas from existing databases of cerebral amyloid angiopathy and hypertensive microangiopathy managed at Nîmes University Hospital;
* Patients who have undergone a follow-up cerebral CT scan in the event of worsening or for follow-up.

Exclusion Criteria:

* Patient refusing to participate

Where it's running

  • CHU de Nîmes
    Nîmes, Gard, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.