Does spinal manipulation help with acute and subacute lower back pain?

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study evaluates the short-term effectiveness of spinal manipulation for acute or subacute non-specific low back pain. Participants must have pain for less than 3 months and a pain intensity above 50/100, and be able to complete online questionnaires. The intervention involves spinal or peripheral manipulation of the lower back, with outcomes focused on pain and functional improvement within the short term. Exclusion criteria include prior spinal surgery, inflammatory or psychiatric conditions, ongoing opioid or corticosteroid therapy, and recent participation in related studies. The study is led by Centre Hospitalier Universitaire de Nîmes at Nîmes University Hospital in France, with no listed collaborators at this time.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients seeking treatment for low back pain present for less than 3 months, with an average intensity greater than 50 on a visual analog scale of 0-100 in the previous 48 hours.
* Patients able to complete online questionnaires.
* Patients who have given their free and informed consent.
* Patients who are affiliated with or beneficiaries of a health insurance plan.

Exclusion Criteria:

* Patients with a history of back surgery, undergoing corticosteroid or morphine treatment, with acute or chronic inflammatory diseases, with psychiatric illness, or with low back pain lasting more than 3 months.
* Patients who have already undergone spinal manipulation for low back pain with the investigator.
* Patients participating or having participated in a therapeutic or drug study in the 3 months prior to their inclusion in this protocol.
* Patients in a period of exclusion determined by another study.
* Patients under legal protection, guardianship, or conservatorship.
* Patients unable to give their consent.
* Patients for whom it is impossible to provide informed consent.
* Pregnant or breastfeeding patients.

Where it's running

• Nimes University Hospital
  Nîmes, Gard, France Recruiting

Study contacts

• Study coordinator: Arnaud DUPEYRON, Professor
• Email: arnaud.dupeyron@umontpellier.fr
• Phone: +33 4.66.68.34.59

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.