Condition

Thrombectomy clinical trials and research

• 14Clinical trials
• 12NIH research projects
• 7Countries

Newest Thrombectomy clinical trials

All recruiting trials (14)

• Intra-arterial Alteplase after successful reperfusion following mechanical thrombectomy

  This trial tests whether giving a small amount of alteplase directly into the artery after a successful thrombectomy helps adults with acute ischemic stroke recover better.

  Recruiting at 9 sites Phase 3 115 People's Hospital · An Giang and 12 other locations · NCT07727395

• Sivelestat added to endovascular clot retrieval for acute anterior circulation stroke

  This study tests whether giving sivelestat sodium alongside mechanical thrombectomy helps improve outcomes for adults with acute ischemic stroke due to large vessel occlusion.

  Recruiting at 2 sites Xuanwu Hospital, Beijing · Weifang, Shandong and 1 other locations · NCT07552610

• Brain blood flow changes after successful clot removal in acute ischemic stroke

  This study will use a special MRI blood-oxygenation breathing test to see if it can detect patients with acute ischemic stroke who do not improve after successful clot removal.

  Recruiting University of Zurich · Zurich, Canton of Zurich · NCT07534319

• Injecting methylprednisolone into the artery right after clot removal for large-vessel stroke

  This trial will test whether giving methylprednisolone into the artery immediately after successful clot removal, followed by three days of IV methylprednisolone, helps adults with anterior large-vessel occlusion strokes recover better.

  Recruiting Phase 2 Tang-Du Hospital · Xi'an, Shaanxi · NCT07516522

• Michigan experience using the Tigertriever device to remove brain clots

  This project tries to see if the Tigertriever device safely and effectively removes large brain clots in adults who have an ischemic stroke within 8 hours of symptom onset.

  Recruiting Henry Ford Health System · Detroit, Michigan · NCT07363525

• Anesthesia choice for mechanical thrombectomy in ischemic stroke

  In people with severe ischemic stroke due to a large vessel blockage who need mechanical thrombectomy, this study tests whether general anesthesia works better than procedural sedation for improving daily function 3 months later.

  Recruiting at 7 sites University Hospital, Clermont-Ferrand · Angers and 15 other locations · NCT07235514

• Predicting recovery after thrombolysis and thrombectomy using brain scan scores

  This project will see if combining standard brain imaging scores can predict 90-day recovery and vessel reopening in adults who had an acute ischemic stroke treated with clot-busting medicine and clot removal.

  Recruiting Centre Hospitalier de Gonesse · Gonesse · NCT07069452

• Using AI to speed up transfers for stroke patients needing thrombectomy

  This study tests if using an AI tool can help speed up the transfer of stroke patients to hospitals that can provide a special treatment called thrombectomy.

  Recruiting at 2 sites Hospital Universitari Vall d'Hebron Research Institute · Granollers, Barcelona and 1 other locations · NCT06741332

• Comparing thrombectomy and medical management for stroke patients treated after 24 hours

  This study is testing if a special procedure to remove blood clots can help stroke patients who arrive more than 24 hours after their symptoms start, compared to just using medication.

  Recruiting Tianjin Huanhu Hospital · Tianjin, Tianjin Municipality · NCT06654375

• Comparing endovascular therapy and best medical treatment for mild acute stroke with large vessel occlusion

  This study is testing whether a special treatment for stroke called endovascular therapy can help people with mild strokes caused by a blocked blood vessel feel better compared to just using standard medical care.

  Recruiting First Affiliated Hospital of Wannan Medical College · Wuhu, Anhui · NCT06143488

• Using two stent retrievers at once versus one for treating acute ischemic stroke

  We will test whether using two stent retrievers at the same time helps people with acute ischemic stroke get their blocked artery opened faster and recover better during mechanical thrombectomy.

  Recruiting at 4 sites Fundación EPIC · Essen and 3 other locations · NCT05930145

• Registry for Endovascular Treatment of Acute Ischemic Stroke

  This study is trying to see how safe and effective a specific treatment for stroke is in helping patients recover after a blocked blood vessel.

  Recruiting Changhai Hospital · Shanghai · NCT05864638

• Moderate CO2 increase during anesthesia to boost collateral flow in clot removal for acute anterior stroke

  This study will test whether slightly higher blood carbon dioxide during anesthesia improves collateral blood flow and protects the brain in people having mechanical thrombectomy for anterior large-vessel ischemic stroke.

  Recruiting Phase 2 University Hospital, Clermont-Ferrand · Clermont-Ferrand · NCT05051397

• Assessing immune responses after acute ischemic stroke treatment

  This study is testing how the immune system reacts in patients treated for an acute ischemic stroke to see if these responses can help predict their recovery after three months.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris, Paris · NCT04663399

NIH-funded research (12)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Robotic ultrasound-guided clot removal for stroke treatment

  A new robot-assisted ultrasound system is being developed to help quickly reopen brain arteries during a stroke, with testing in patient-specific 3D-printed models and animal studies.

  NIH research Georgia Institute of Technology · Atlanta, United States · NIH-11510958

• Modeling Acute Ischemic Stroke to Improve Mechanical Thrombectomy

  A research project is creating better computer models and animal studies to help remove clots more safely and effectively in people who have an acute ischemic stroke.

  NIH research Pennsylvania State University, the · University Park, United States · NIH-11464942

• Milli-spinner thrombectomy for faster clot removal in acute brain stroke

  A new, spinner-based clot-removal device is being studied to remove brain clots more quickly and safely in stroke patients.

  NIH research Stanford University · Stanford, United States · NIH-11457969

• Predictors of recovery after stroke in rural Appalachia

  This project tests blood protein markers to predict cognitive recovery after a stroke treated with thrombectomy, focusing on rural Appalachian patients.

  NIH research University of Kentucky · Lexington, United States · NIH-11362286

• Precise imaging to guide thrombectomy for posterior circulation strokes

  A study at Stanford will test whether special brain imaging helps doctors decide which patients with rare posterior circulation strokes should get thrombectomy.

  NIH research Stanford University · Stanford, United States · NIH-11345266

• Predicting Mechanical Thrombectomy Outcomes with Smart, Transparent AI

  A patient-friendly look at how new AI models may predict how well mechanical thrombectomy could work for individuals with acute ischemic stroke.

  NIH research Northwestern University · Chicago, United States · NIH-11290590

• Improving treatment for severe strokes using advanced techniques

  This study is looking at how well a special procedure called endovascular thrombectomy (EVT) works for people having a stroke caused by blocked blood vessels, and it aims to find out if new tools and treatments can help even more patients recover better.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-11237311

• Using imaging to find candidates for thrombectomy in posterior circulation strokes

  This study is looking at new imaging methods to help doctors find out if patients with certain types of strokes in the back of the brain can benefit from a specific treatment called thrombectomy, so if you’ve had a stroke caused by blocked arteries in that area, this research might help improve your treatment options.

  NIH research Stanford University · Stanford, United States · NIH-11060021

• Improving stroke treatment with a new catheter device for easier access.

  This study is testing a new catheter device that helps doctors remove blood clots in the brain through the wrist instead of the groin, aiming to make the treatment for stroke patients safer and more effective.

  NIH research Piraeus Medical, INC. · Rochester, United States · NIH-10932227

• Improving treatment for acute ischemic stroke using advanced modeling techniques

  This study is looking at how blood clots form in the brain and why some can be removed easily while others can't, with the goal of helping doctors improve treatments for people who have had a stroke.

  NIH research Pennsylvania State University, the · University Park, United States · NIH-10613506

• Investigating the benefits of endovascular thrombectomy for stroke patients.

  This study is looking to find better treatment options for people who have had a stroke caused by a blocked blood vessel, by testing a procedure called endovascular thrombectomy (EVT) on a broader group of patients to see how well it works.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-10547985

• Developing a smart catheter to improve blood clot removal in stroke treatment

  This study is testing a new smart catheter that helps doctors remove blood clots during stroke treatment by giving them real-time information about how the procedure is going, making it safer and more effective for patients.

  NIH research Worcester Polytechnic Institute · Worcester, United States · NIH-10514898

Related topics

Quick answers

How many Thrombectomy clinical trials are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in China (5 trials), France (4 trials), Spain (2 trials), Switzerland (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →