Using imaging to find candidates for thrombectomy in posterior circulation strokes
Official title: PRECISE (PeRfusion imaging to identify postErior CIrculation candidateS for thrombectomy)
Funded at Stanford University · NIH-11060021 · Data updated 2026-11-12
This study is looking at new imaging methods to help doctors find out if patients with certain types of strokes in the back of the brain can benefit from a specific treatment called thrombectomy, so if you’ve had a stroke caused by blocked arteries in that area, this research might help improve your treatment options.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | August 1, 2021 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $1,438,776 |
| NIH project number | 5R01NS121720-04 |
| Project ID | NIH-11060021 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults experiencing acute ischemic strokes due to vertebral or basilar artery occlusions within 24 hours of symptom onset.
✕Less likely to help
Patients who do not have occlusions in the vertebral or basilar arteries or those who are not experiencing acute ischemic strokes may not benefit from this research.
What this research studies
This research investigates the use of advanced imaging techniques to identify patients with acute ischemic strokes caused by occlusions in the vertebral or basilar arteries who may benefit from thrombectomy. Patients will undergo CT or MRI cerebral perfusion imaging within 24 hours of symptom onset to assess their eligibility for this treatment. The study aims to fill a critical gap in knowledge regarding treatment options for this high-risk group, as they have been largely excluded from previous trials. By determining the effectiveness of these imaging strategies, the research seeks to improve clinical outcomes for patients suffering from posterior circulation strokes.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and outcomes for patients experiencing posterior circulation strokes.
How similar studies have gone: While there has been significant research on anterior circulation strokes, this approach focusing on posterior circulation strokes is relatively novel and has not been extensively tested in prior studies.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Albers, Gregory W — Stanford University
- Study coordinator: Albers, Gregory W
Related research
Other NIH-funded projects on the same topics.
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Robotic ultrasound-guided clot removal for stroke treatment
A new robot-assisted ultrasound system is being developed to help quickly reopen brain arteries during a stroke, with testing in patient-specific 3D-printed models and animal studies.
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Modeling Acute Ischemic Stroke to Improve Mechanical Thrombectomy
A research project is creating better computer models and animal studies to help remove clots more safely and effectively in people who have an acute ischemic stroke.
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Milli-spinner thrombectomy for faster clot removal in acute brain stroke
A new, spinner-based clot-removal device is being studied to remove brain clots more quickly and safely in stroke patients.
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Predictors of recovery after stroke in rural Appalachia
This project tests blood protein markers to predict cognitive recovery after a stroke treated with thrombectomy, focusing on rural Appalachian patients.
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Precise imaging to guide thrombectomy for posterior circulation strokes
A study at Stanford will test whether special brain imaging helps doctors decide which patients with rare posterior circulation strokes should get thrombectomy.
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Predicting Mechanical Thrombectomy Outcomes with Smart, Transparent AI
A patient-friendly look at how new AI models may predict how well mechanical thrombectomy could work for individuals with acute ischemic stroke.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.