Investigating the benefits of endovascular thrombectomy for stroke patients.
Official title: StrokeNet Thrombectomy Endovascular Platform (STEP)
Funded at Medical University of South Carolina · NIH-10547985 · Data updated 2026-11-12
This study is looking to find better treatment options for people who have had a stroke caused by a blocked blood vessel, by testing a procedure called endovascular thrombectomy (EVT) on a broader group of patients to see how well it works.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical University of South Carolina NIH-funded |
| Lab location | 1 site (Charleston, United States) |
| Project start | September 1, 2022 |
| Project end | December 31, 2025 |
| Funding year | 2022 |
| Award (this year) | $310,411 |
| NIH project number | 1OT2NS129366-01 |
| Project ID | NIH-10547985 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients experiencing acute ischemic stroke with large vessel occlusion who may be eligible for endovascular thrombectomy.
✕Less likely to help
Patients with strokes not caused by large vessel occlusion or those who are not candidates for endovascular thrombectomy may not benefit from this research.
What this research studies
This research focuses on improving treatment options for patients suffering from acute ischemic stroke, particularly those with large vessel occlusion. It aims to assess the effectiveness of endovascular thrombectomy (EVT) in a wider range of patients than previously studied. The research will utilize a multi-factorial, adaptive trial design to explore various aspects of EVT, including its indications, devices, and accompanying medical therapies. By developing a robust clinical trial platform, the study seeks to provide clearer answers regarding the management of stroke patients who may benefit from EVT.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment protocols for stroke patients, potentially reducing disability and enhancing recovery outcomes.
How similar studies have gone: Previous studies have shown that endovascular thrombectomy can be highly beneficial for selected stroke patients, indicating a promising avenue for further exploration.
Where this research is happening
-
Medical University of South Carolina
Charleston, United States Active
Researchers
- Principal investigator: Elm, Jordan J. — Medical University of South Carolina
- Study coordinator: Elm, Jordan J.
Related research
Other NIH-funded projects on the same topics.
-
Robotic ultrasound-guided clot removal for stroke treatment
A new robot-assisted ultrasound system is being developed to help quickly reopen brain arteries during a stroke, with testing in patient-specific 3D-printed models and animal studies.
-
Modeling Acute Ischemic Stroke to Improve Mechanical Thrombectomy
A research project is creating better computer models and animal studies to help remove clots more safely and effectively in people who have an acute ischemic stroke.
-
Milli-spinner thrombectomy for faster clot removal in acute brain stroke
A new, spinner-based clot-removal device is being studied to remove brain clots more quickly and safely in stroke patients.
-
Predictors of recovery after stroke in rural Appalachia
This project tests blood protein markers to predict cognitive recovery after a stroke treated with thrombectomy, focusing on rural Appalachian patients.
-
Precise imaging to guide thrombectomy for posterior circulation strokes
A study at Stanford will test whether special brain imaging helps doctors decide which patients with rare posterior circulation strokes should get thrombectomy.
-
Predicting Mechanical Thrombectomy Outcomes with Smart, Transparent AI
A patient-friendly look at how new AI models may predict how well mechanical thrombectomy could work for individuals with acute ischemic stroke.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.