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Ischemic Stroke, Acute clinical trials and research

• 21Clinical trials
• 13Countries

Newest Ischemic Stroke, Acute clinical trials

All recruiting trials (21)

• AI-powered decision support to boost thrombolysis for ischemic stroke

  This trial tests whether an AI-assisted decision tool helps doctors give intravenous thrombolysis to eligible ischemic stroke patients within 24 hours at a primary hospital in China, compared with standard care.

  Recruiting Capital Medical University · Changsha, Hunan · NCT07785492

• Tegoprazan to prevent GI complications in ischemic stroke patients on antiplatelet therapy

  This trial tests whether tegoprazan can lower gastrointestinal complications in adults with ischemic stroke or TIA who are starting antiplatelet therapy.

  Recruiting at 24 sites Phase 3 Hanyang University · Busan, Busan and 23 other locations · NCT07687706

• Intra-arterial Thrombolysis for Acute Ischemic Stroke with Medium Vessel Occlusion

  This trial tests whether delivering a clot-busting medicine directly into the brain’s medium vessels helps improve outcomes for adults with acute ischemic stroke caused by MeVO, on top of standard care.

  Recruiting Phase 3 The First Affiliated Hospital with Nanjing Medical University · Nanjing, Jiangsu · NCT07668323

• Single Bolus Non-immunogenic Staphylokinase in Acute Ischemic Stroke (4.5–24 hours)

  This trial tests a single 10 mg bolus of non-immunogenic staphylokinase versus placebo in adults with acute ischemic stroke 4.5–24 hours after onset to see if it helps restore blood flow and improve outcomes.

  Recruiting at 10 sites Phase 3 Supergene, LLC · Ryazan, Ryazan Oblast and 16 other locations · NCT07324837

• Imaging to detect impaired microcirculatory reperfusion after clot removal

  This project tests whether CT perfusion scans done after clot removal can spot poor tiny-vessel blood flow in adults with large-vessel ischemic stroke.

  Recruiting University of Cincinnati · Cincinnati, Ohio · NCT07099599

• Cerebrolysin for early rehabilitation after acute ischemic stroke

  This trial tests whether adding Cerebrolysin to standard early rehabilitation helps people with moderate acute ischemic stroke recover arm and overall function faster.

  Recruiting University Medical Centre Ljubljana · Ljubljana · NCT07043686

• Comparing two imaging techniques for detecting arterial obstructions in stroke patients

  This study is testing whether a new imaging method called TCCD is better than CT angiography for finding blocked arteries in stroke patients, especially in the Egyptian population.

  Recruiting Sohag University · Sohag · NCT06920303

• Using AI to speed up transfers for stroke patients needing thrombectomy

  This study tests if using an AI tool can help speed up the transfer of stroke patients to hospitals that can provide a special treatment called thrombectomy.

  Recruiting at 2 sites Hospital Universitari Vall d'Hebron Research Institute · Granollers, Barcelona and 1 other locations · NCT06741332

• Comparing two bevifibatide dose regimens for acute ischemic stroke

  This trial will test whether two different maintenance doses of bevifibatide improve 90-day neurological recovery and reduce symptomatic brain bleeding in people with acute ischemic stroke who do not have large or medium vessel occlusion.

  Recruiting Phase 2 Zhujiang Hospital · Guangzhou, Guangdong · NCT06712004

• Transcranial magnetic stimulation after thrombectomy for acute ischemic stroke

  This trial will try short sessions of continuous theta-burst transcranial magnetic stimulation (cTBS) to help recovery in adults who had an acute anterior-circulation ischemic stroke and successful endovascular thrombectomy.

  Recruiting Xijing Hospital · Xi'an, Shaanxi · NCT06639360

• Analyzing multi-omics data to predict outcomes in acute ischemic stroke patients

  This study is trying to see if analyzing blood and stool samples from people who have had a stroke can help predict their recovery and chances of having another stroke.

  Recruiting Nanfang Hospital, Southern Medical University · Guangzhou, Guangdong · NCT06584565

• Comparing blood pressure management strategies after stroke treatment

  This study is testing different ways to manage blood pressure in stroke patients who have had a specific treatment to see which method helps them recover better and reduces risks.

  Recruiting at 2 sites The George Institute · Sydney, New South Wales and 1 other locations · NCT06352619

• Tirofiban treatment for patients with high-risk cerebrovascular events

  This study is testing whether the drug tirofiban can help prevent new strokes in people aged 40 and older who have had serious but non-disabling cerebrovascular events.

  Recruiting at 5 sites Phase 3 Beijing Tiantan Hospital · Harbin, Heilongjiang and 4 other locations · NCT06319846

• Using Shuxuening Injection to enhance treatment for ischemic stroke

  This study is testing if a new injection called Shuxuening can help people recover better from an ischemic stroke when given alongside standard treatment.

  Recruiting at 82 sites Phase 3 Beijing Tiantan Hospital · Beijing, Beijing Municipality and 81 other locations · NCT06157502

• Improving emergency evaluation and transfer protocols for stroke patients

  This study is testing a new way to speed up the transfer of stroke patients to specialized hospitals to see if it helps them get better faster.

  Recruiting at 8 sites University of Chicago · New Haven, Connecticut and 7 other locations · NCT06094478

• Assessing long-term outcomes of LAA contrast flow after heart procedure

  This study looks at how well heart devices used to close the left atrial appendage work over time in patients, especially those at high risk, to see if they prevent leaks, blood clots, and strokes.

  Recruiting Kansas City Heart Rhythm Research Foundation · Overland Park, Kansas · NCT06075628

• Intra-arterial tenecteplase given after thrombectomy for anterior large-vessel ischemic stroke with no-reflow or residual clot

  This trial will test whether giving tenecteplase directly into the artery at the end of thrombectomy helps people with anterior large-vessel ischemic stroke treated within 24 hours of symptom onset.

  Recruiting at 11 sites Phase 2/3 University of Melbourne · Gold Coast, Queensland and 11 other locations · NCT05892510

• Using brain stimulation to improve motor recovery after stroke

  This study is testing if a special brain stimulation technique can help people recover better movement in their arms after having a stroke.

  Recruiting at 4 sites University Hospital Tuebingen · Frankfurt a.M., Frankfurt a.M. and 3 other locations · NCT05600374

• Investigating how circadian factors affect recovery from ischemic stroke

  This study is testing if different combinations of blue light and melatonin can help people recover better from an ischemic stroke by looking at their sleep and brain healing over three months.

  Recruiting Phase 4 Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health · Saint Petersburg · NCT05247125

• Evaluating the effectiveness of Tenecteplase for treating certain ischemic strokes

  This study is testing if a new stroke treatment called Tenecteplase can help people who had certain types of strokes feel better compared to a placebo.

  Recruiting at 15 sites Phase 3 Hospital Moinhos de Vento · Porto Alegre, Rio Grande do Sul and 14 other locations · NCT05199662

• Moderate CO2 increase during anesthesia to boost collateral flow in clot removal for acute anterior stroke

  This study will test whether slightly higher blood carbon dioxide during anesthesia improves collateral blood flow and protects the brain in people having mechanical thrombectomy for anterior large-vessel ischemic stroke.

  Recruiting Phase 2 University Hospital, Clermont-Ferrand · Clermont-Ferrand · NCT05051397

Related topics

Quick answers

How many Ischemic Stroke, Acute clinical trials are recruiting right now?

21, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in China (7 trials), United States (3 trials), Russia (2 trials), Australia (2 trials), New Zealand (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 6, Phase 2: 2, Phase 2/3: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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