Developing a smart catheter to improve blood clot removal in stroke treatment

Smart Aspiration Catheter Based on Fiber Optic Pressure Sensing for Mechanical Thrombectomy in Stroke

NIH-funded research Worcester Polytechnic Institute · NIH-10514898

This study is testing a new smart catheter that helps doctors remove blood clots during stroke treatment by giving them real-time information about how the procedure is going, making it safer and more effective for patients.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionWorcester Polytechnic Institute NIH-funded
Lab location1 site (Worcester, United States)
Project IDNIH-10514898 on NIH RePORTER

What this research studies

This research focuses on enhancing the mechanical thrombectomy procedure used to treat acute ischemic strokes by developing a smart aspiration catheter equipped with fiber optic pressure sensors. These sensors will provide real-time feedback on the interaction between the catheter, blood clot, and artery, helping physicians make informed decisions during the procedure. The study aims to identify critical conditions such as gaps between the catheter and clot, catheter jams, artery collapses, and clot breakage, which can lead to complications and poor outcomes. By improving the safety and effectiveness of clot removal, this research seeks to reduce the risks associated with current thrombectomy methods.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing acute ischemic strokes caused by large vessel occlusion.

Not a fit: Patients with strokes not caused by large vessel occlusion or those who are not candidates for mechanical thrombectomy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective treatments for stroke patients, potentially improving recovery outcomes.

How similar studies have performed: Previous research has shown promise in using advanced sensing technologies in medical devices, suggesting potential success for this novel approach.

Where this research is happening

Worcester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.