Condition

Risk Factors clinical trials and research

• 10Clinical trials
• 352NIH research projects
• 8Countries

Newest Risk Factors clinical trials

All recruiting trials (10)

• Falls in Spanish people with intellectual disabilities: what puts them at risk and a way to predict future falls

  This study tests which factors are linked to falling in adults with intellectual disabilities in Spain to build a formula that can predict future falls.

  Recruiting Fundación Hospitalarias Betanzos · Betanzos, A Coruña · NCT07282704

• H. pylori in stomach cancers in the French West Indies

  This project will test how common H. pylori infection is in adults newly diagnosed with stomach cancer in Guadeloupe.

  Recruiting at 2 sites Centre Hospitalier Universitaire de la Guadeloupe · Baie-Mahault and 1 other locations · NCT07233447

• Optimizing management of precancerous cervical lesions in women with HPV

  This study is testing how to better manage cervical lesions in women with high-risk HPV by looking at how these lesions change over two years.

  Recruiting Faculty Hospital Kralovske Vinohrady · Prague · NCT06967740

• Training community members to be HealthyLifetime health coaches

  This trial will test whether community members trained as health coaches can do as well as nurse health coaches at delivering the HealthyLifetime virtual program to adults without complex chronic conditions.

  Recruiting University of Michigan · Ann Arbor, Michigan and 1 other locations · NCT06616246

• Whether intense pain before emergency surgery leads to long-term pain after the operation

  We will test whether people having emergency abdominal or orthopedic surgery who have strong pain before the operation are more likely to have ongoing pain three months afterward.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT06555107

• Lowering pneumothorax risk during CT-guided lung biopsy with small pleural fluid and targeted positioning

  This study will see if injecting a small amount of fluid into the pleural space and positioning the patient so the biopsy site is gravity-dependent can lower the chance of a pneumothorax in adults having CT-guided percutaneous lung biopsy.

  Recruiting Insel Gruppe AG, University Hospital Bern · Bern · NCT06340178

• Online survey to assess health risk factors and drug interactions

  This study is trying to see how common health risks and drug interactions are among people by having them fill out an online survey about their medications and health habits.

  Recruiting Tomsk National Research Medical Center of the Russian Academy of Sciences · Tomsk · NCT06159699

• Investigating genetic and environmental factors in cardiovascular and renal diseases

  This study looks at how genes and the environment affect heart and kidney health over time in families to help us understand what can lead to diseases.

  Recruiting Central Hospital, Nancy, France · Vandœuvre-lès-Nancy, Lorraine · NCT05916287

• Identifying risk factors and outcomes for patients needing acute surgical care

  This study looks at patients who needed emergency surgery to see what factors might lead to complications or death, helping to improve future treatments and care.

  Recruiting Region Skane · Malmö, Skåne County · NCT05195697

• Health dialogues to improve cardiovascular health in Skåne

  This study is testing a program that has health conversations with 40-year-olds in Skåne to see if it can help improve their heart health.

  Recruiting Region Skane · Malmö, Skåne County · NCT04912739

NIH-funded research (newest 40 of 352)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• IOP and CSF Pressure in Glaucoma Risk

  This grant studies how eye pressure and cerebrospinal fluid pressure together influence glaucoma risk and vision loss.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11644421

• ALS risk factors in a long-term ALS study

  A long-term ALS study is looking at which factors may influence disease risk and progression in people living with ALS.

  NIH research Als Therapy Development Foundation · Watertown, United States · NIH-11631679

• Understanding how work exposures and genes influence ALS risk

  A study is building a long-term group of people at higher risk for ALS to see how their jobs, exposures at work, and genes together affect if and when the disease might develop.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11631673

• P-CARRS-BRAIN: Predicting Alzheimer’s risk in South Asians in India using genetic, behavior, and vascular data

  Aims to predict Alzheimer’s disease risk in middle-aged South Asians by combining genetic, lifestyle, and vascular information to catch early changes before dementia develops.

  NIH research Emory University · Atlanta, United States · NIH-11604418

• P-CARRS-BRAIN: Predicting Alzheimer’s risk in South Asians in India using genetics, behavior, and vascular data

  Aimed at people 21 and older, this project looks at how biology, behavior, and blood vessel health together may signal the early risk of Alzheimer’s disease and related dementias in South Asians.

  NIH research Emory University · Atlanta, United States · NIH-11604417

• Understanding how risk factors affect progression of cirrhosis and response to statins in patients with cirrhosis

  This project follows people with cirrhosis to see what factors speed up their liver disease and whether statin medicines help prevent worsening.

  NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11591513

• Sex-specific blood biomarkers predict dementia risk in older adults

  This NIH project tests how blood biomarkers and sex differences predict future dementia in older people, with the goal of personalized prognosis and prevention.

  NIH research Hennepin Healthcare Research Institute · Minneapolis, United States · NIH-11588438

• Zoonotic UPEC in Northwest Ecuador: Who gets UTIs and how it spreads

  Researchers will explore how uro-pathogenic E. coli from animals and the environment may cause UTIs in people in Northwest Ecuador.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11565199

• Modifiable risk factors and midlife thinking and memory in diverse groups

  A study to understand how manageable lifestyle factors affect thinking skills in midlife adults from diverse backgrounds.

  NIH research New York University School of Medicine · New York, United States · NIH-11539200

• PTSD and Autoimmune Diseases: How PTSD Might Cause or Change Risk and What Might Help

  This project looks at whether PTSD in Veterans affects the risk of autoimmune diseases and whether there are factors that influence that risk.

  NIH research Veterans Affairs Med Ctr San Francisco · San Francisco, United States · NIH-11538983

• Understanding CKDu risk factors and predictors in Central America’s farming communities

  A study in rural Central America will follow young agricultural workers to find factors linked to kidney decline and identify biomarkers that could predict CKDu.

  NIH research Universidad Nacional, Costa Rica · Heredia, Costa Rica · NIH-11528624

• Understanding CKDu risk factors in agricultural Central America

  This grant tests what factors put agricultural workers in four Central American countries at risk for chronic kidney disease of unknown origin (CKDu) and what predicts kidney function decline.

  NIH research Universidad Nacional, Costa Rica · Heredia, Costa Rica · NIH-11520955

• Pathways and Molecules to Prevent Early-Onset Colorectal Tumors

  This NIH project aims to understand and prevent colorectal cancer that occurs before age 50 by studying lifestyle, biology, and environmental factors that influence risk.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11514462

• Pathways and factors to prevent early-onset colorectal tumors

  This NIH grant would explore why colorectal cancer is rising in people under 50 and identify clues we can use to prevent it.

  NIH research Harvard University · Cambridge, United States · NIH-11514461

• Pathways and Molecules to Prevent Early-Onset Colorectal Tumors

  A project at the Broad Institute aims to understand why colorectal cancer is increasing in people under 50 and identify ways to prevent it.

  NIH research Broad Institute, INC. · Cambridge, United States · NIH-11514460

• Understanding lung problems that linger after TB treatment in Peru

  A study following people who were treated for TB in Lima, Peru to see what kinds of long-lasting lung problems they have and what factors put them at risk.

  NIH research Harvard Medical School · Boston, United States · NIH-11511777

• How teens build reading understanding and what helps or holds them back

  This project looks at how reading comprehension develops from middle to high school and which cognitive, motivational, and school factors help or hinder teens' ability to understand complex texts.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11508814

• How sleep and body temperature affect Alzheimer's risk in adults with Down syndrome

  Researchers will follow adults with Down syndrome over several years to learn whether sleep problems and lower body temperature are linked to earlier Alzheimer's changes.

  NIH research New York University School of Medicine · New York, United States · NIH-11508145

• Understanding sudden unexpected infant deaths in Zambia and nearby African countries

  This project looks at how often sudden unexpected deaths happen in infants in Zambia and nearby African countries and which common, changeable factors may increase the risk.

  NIH research Boston University Medical Campus · Boston, United States · NIH-11468172

• Teen Period app study to understand menstruation and iron deficiency in newly tapped teens

  A national study using a teen-friendly mobile app to track menstruation and identify factors linked to iron deficiency in girls who have just started menstruating.

  NIH research Research Inst Nationwide Children's Hosp · Columbus, United States · NIH-11466141

• Blocking a blood-vessel protein to protect the brain after COVID-19

  Researchers are testing whether a drug that blocks the alpha5beta1 integrin can protect the brain and reduce memory and thinking problems after COVID-19 or in people with vascular dementia.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11457047

• Sleep and body temperature changes linked to Alzheimer’s risk in adults with Down syndrome

  This project looks at whether sleep problems and lower body temperature in adults with Down syndrome are linked to higher chances of developing Alzheimer’s disease.

  NIH research New York University School of Medicine · New York, United States · NIH-11456945

• Risk factors for alpha-gal allergy and tick bites in people with Anderson-Fabry disease

  A research project investigates why some people, including those with Anderson-Fabry disease, develop alpha-gal allergy after a tick bite and how genetics and tick saliva contribute.

  NIH research Kansas State University · Manhattan, United States · NIH-11456513

• New-onset Depression After Surgery in Older Adults

  A large study will look at why some older adults develop depression after surgery, and what helps or hurts their recovery.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11450807

• Understanding why DCIS becomes invasive breast cancer in Asian American and Native Hawaiian/Pacific Islander groups

  A research project aims to identify biological factors and risk patterns that predict when early-stage DCIS may progress to invasive breast cancer, with a focus on AANHPI populations.

  NIH research University of Hawaii at Manoa · Honolulu, United States · NIH-11449258

• Risk factors and biomarkers for progression of subclinical RA-related lung disease

  This study follows people with rheumatoid arthritis to understand who develops lung disease and what biomarkers predict it.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11447980

• Menopause, aging and brain health: how midlife changes affect Alzheimer’s risk

  This study follows women who were part of a large midlife health study to see how menopause and related factors relate to brain biomarkers and memory later in life.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11447728

• Data-driven look at walkability and safety for older adults

  A small, patient-friendly study aims to understand what makes neighborhoods easier or harder to walk for adults aged 21 and older, focusing especially on older adults.

  NIH research University of Texas Arlington · Arlington, United States · NIH-11445929

• Hypnotic Resistance in Insomnia: How Common It Is and What Increases Risk

  This NIH grant explores why some people with insomnia don’t respond to hypnotic meds and what factors, including genetics, predict this resistance.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11445263

• How lifestyle factors together affect cognitive aging in adults 55+

  A long-term study will look at how things like activity, smoking, drinking, body weight, and social connections influence brain aging in adults 55 and older.

  NIH research University of Memphis · Memphis, United States · NIH-11438697

• Understanding dry mouth in adults using AI to read electronic records

  A new project uses AI to find adults with xerostomia in medical records and predict who will have worse oral health outcomes.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11437326

• Understanding Multilevel Drivers of Stimulant Overdose in the US

  Researchers will look at how social, health, and supply factors combine to influence stimulant overdose deaths, using data from large populations and conversations with people who use stimulants and the clinicians who care for them.

  NIH research Brown University · Providence, United States · NIH-11432076

• Graph-based AI to detect hospital-onset sepsis and find modifiable hospital factors

  A patient-friendly program uses advanced computer models to spot hospital-onset sepsis early and uncover hospital practices that can be changed to reduce risk.

  NIH research Washington University · Saint Louis, United States · NIH-11428470

• Nationwide diabetes surveillance for youth and young adults

  A nationwide system will track how many young people have diabetes, how many are newly diagnosed, and what factors affect risk and disparities.

  NIH research Emory University · Atlanta, United States · NIH-11423373

• How respiratory virus vaccines protect people in Cleveland across health and social backgrounds

  This project is looking at how well flu, COVID-19, and other respiratory virus vaccines keep children and adults from getting sick when they visit outpatient clinics in Cleveland.

  NIH research University Hospitals of Cleveland · Cleveland, United States · NIH-11423354

• Clonal blood changes, social factors, and aging in people with HIV

  This project looks at how blood cell changes, aging markers, and social/behavioral factors might predict faster aging in people living with HIV.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11419901

• Understanding long-term lung problems after TB treatment and who’s at risk in Peru

  This study looks at people who were successfully treated for TB in Lima, Peru, to see how common long-lasting lung problems are and who is most at risk.

  NIH research Harvard Medical School · Boston, United States · NIH-11418869

• Could environmental factors in Central Virginia be linked to ALS clusters

  A study exploring whether local environmental exposures in Central Virginia are connected to clusters of ALS cases and what this could mean for prevention.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11418689

• Understanding dengue in Bamako: how common severe dengue is and what raises risk

  This project study aims to understand how dengue fever spreads and what factors make severe illness more likely among people in urban Bamako, Mali.

  NIH research Univ of Sciences, Tech & Tech of Bamako · Bamako, Mali · NIH-11417996

• Understanding how social factors, sleep, and biology relate to Alzheimer’s risk in older Chinese Americans

  A long-term study will look at how social factors, sleep, brain imaging, and blood biomarkers relate to Alzheimer’s risk in foreign- and native-born older Chinese Americans.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11417958

Related topics

Quick answers

How many Risk Factors clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in France (2 trials), Sweden (2 trials), Czechia (1 trial), Guadeloupe (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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