Understanding dengue in Bamako: how common severe dengue is and what raises risk
Official title: Understanding the persistence of Dengue epidemic and associated risk factors in Urban Bamako Mali
Funded at Univ of Sciences, Tech & Tech of Bamako · NIH-11417996 · Data updated 2026-11-12
This project study aims to understand how dengue fever spreads and what factors make severe illness more likely among people in urban Bamako, Mali.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Sciences, Tech & Tech of Bamako NIH-funded |
| Lab location | 1 site (Bamako, Mali) |
| Project start | September 18, 2025 |
| Project end | August 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $146,210 |
| NIH project number | 5R01AI191323-02 |
| Project ID | NIH-11417996 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal participants are individuals in urban Bamako and rural Mali who present with fever and consent to blood tests and follow-up surveys.
✕Less likely to help
Some individuals tested may not have dengue or may not experience severe disease, so direct benefits could be limited for them.
What this research studies
Researchers will combine hospital and community fever tracking with blood surveys and genetic analysis of dengue viruses to map how dengue behaves in Bamako and nearby areas. The study will look at how many febrile patients have dengue, who is at higher risk for severe disease, and how prior exposure shapes outcomes. By linking clinical data with viral genetics, the project hopes to identify transmission patterns and key determinants of severity that can guide public health actions and vaccines. The findings will inform health officials and travelers about risk and prevention strategies in West Africa.
Why it matters
Potential benefit: If successful, the work could improve dengue prevention, diagnosis, and management for people in Mali and similar settings, potentially reducing severe cases and deaths.
How similar studies have gone: Previous dengue studies have shown that combining clinical data with viral genetics can uncover transmission patterns and severity factors, supporting the potential value of this approach in Mali.
Where this research is happening
-
Univ of Sciences, Tech & Tech of Bamako
Bamako, Mali Active
Researchers
- Principal investigator: Kane, Fousseyni — Univ of Sciences, Tech & Tech of Bamako
- Study coordinator: Kane, Fousseyni
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.