Condition

Chronic Postsurgical Pain clinical trials and research

• 9Clinical trials
• 2New in 30 days
• 5Countries

Newest Chronic Postsurgical Pain clinical trials

All recruiting trials (9)

• Phenotype-based pain management for chronic post-treatment pain after head and neck cancer

  We’re testing a personalized pain plan to see if tailoring treatment to a patient’s pain type can reduce chronic pain in adults who completed head and neck cancer treatment.

  Recruiting Phase 2 Shaukat Khanum Memorial Cancer Hospital & Research Centre · Lahore, Punjab Province · NCT07919457

• Postoperative Pain Trajectories After Endometriosis Surgery

  This study tests how pain changes after endometriosis surgery and whether perioperative pain testing can predict who will have ongoing pain.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07882498

• Prevention of chronic postsurgical pain in people who regularly use opioids

  This trial tests whether adding a telemedicine post-surgery consult between days 15 and 28 helps reduce long-term pain and opioid use in adults on chronic opioids undergoing elective surgery.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07717151

• Oliceridine PCIA for Postoperative Pain After VATS Lung Resection

  This trial tests whether oliceridine given through patient-controlled IV analgesia reduces the risk of chronic pain after lung surgery done with video-assisted techniques, compared with sufentanil.

  Recruiting at 7 sites Phase 4 Tianjin Medical University General Hospital · Baoding, Hebei and 6 other locations · NCT07018375

• Intertransverse process block to improve recovery and cut long-term pain after open-heart surgery

  We will test whether giving an intertransverse process block during elective open-heart (CABG or valve) surgery helps adults recover better after surgery and reduces the chance of long-term post-surgery pain.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT06946290

• Whether intense pain before emergency surgery leads to long-term pain after the operation

  We will test whether people having emergency abdominal or orthopedic surgery who have strong pain before the operation are more likely to have ongoing pain three months afterward.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT06555107

• Esketamine dose levels combined with dexmedetomidine to reduce pain after scoliosis correction

  This study will test whether different doses of esketamine given with dexmedetomidine and opioids can reduce immediate postoperative pain and lower the chance of chronic postsurgical pain in adults having scoliosis correction.

  Recruiting Phase 4 Peking University First Hospital · Beijing, Beijing Municipality · NCT06087510

• Reducing oxidative stress to prevent chronic pain after knee surgery

  This study is testing if a special antioxidant can help people who have knee surgery feel less pain and recover better.

  Recruiting Phase 4 Vanderbilt University Medical Center · Nashville, Tennessee · NCT06083480

• Platelet-rich fibrin to reduce pain after lumbar disc surgery

  This phase 3 trial tests whether applying platelet-rich fibrin around the nerve roots during lumbar disc surgery can lessen ongoing neuropathic pain after the operation.

  Recruiting Phase 3 University Hospital, Strasbourg, France · Strasbourg, Bas-Rhin · NCT05196503

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Quick answers

How many Chronic Postsurgical Pain clinical trials are recruiting right now?

9, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in France (4 trials), China (2 trials), United States (1 trial), Hong Kong (1 trial), Pakistan (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3, Phase 3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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