Whether intense pain before emergency surgery leads to long-term pain after the operation
Official title: Acute Preoperative Pain and Chronic Post-surgical Pain in Emergency Surgery
Run by Centre Hospitalier Universitaire, Amiens · NCT06555107 · Data updated 2026-11-12
We will test whether people having emergency abdominal or orthopedic surgery who have strong pain before the operation are more likely to have ongoing pain three months afterward.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 693 (estimated) |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens) |
| Status | Recruiting |
| Started | August 29, 2024 |
| Main results expected | January 2027 |
| Study ends | April 2027 |
| Registry record updated | January 16, 2026 |
| Trial ID | NCT06555107 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (age ≥18) having emergency orthopedic or abdominal surgery who can give informed consent, communicate in French, self-rate pain, and are affiliated with a social security scheme are ideal candidates.
✕Probably not a fit
Patients admitted to postoperative intensive care, having ambulatory or endoscopic procedures, repeat surgery at the same site within three months, pregnant or breastfeeding individuals, those with significant psychiatric or neurodegenerative disorders, or those unable to self-report pain are unlikely to benefit from this study's findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults undergoing emergency abdominal or orthopedic surgery at a single university hospital will report their preoperative pain intensity using a numerical scale. Data will be collected with questionnaires and follow-up phone calls, and outcomes will include the presence of chronic postsurgical pain at three months. Patients requiring postoperative ICU, undergoing ambulatory or endoscopic procedures, or unable to self-report pain are excluded. The study is conducted at CHU Amiens-Picardie with enrollment limited to patients able to consent and communicate in French.
Why it matters
Potential benefit: If successful, this could help identify patients at higher risk of chronic postsurgical pain so clinicians can target prevention and pain management earlier.
How similar studies have gone: Previous work in scheduled surgery links preoperative pain to worse short-term postoperative pain, but the long-term effects of acute preoperative pain in emergency surgery remain largely untested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 years old. * Emergency orthopaedic and/or abdominal surgery. * Informed consent. * Affiliation to a social security scheme Exclusion Criteria: * Intraoperative complications that are life-threatening or require the surgical procedure to be discontinued. * Post-operative intensive care unit admission. * Ambulatory surgery. * Endoscopic surgery. * Repeat surgery at the same site in less that 3months. * Pregnant or breast-feeding patients. * Patients under guardianship or deprived of liberty. * Patients suffering from psychiatric pathologies. * Patients suffering from neurodegenerative pathologies. * Patients for whom self-assessment of pain using a numerical scale (0-10) cannot be carried out (non-communicative patients, non-French-speaking patients, and so on).
Where it's running
-
CHU Amiens-Picardie
Amiens, France Recruiting
Study contacts
- Study coordinator: Paul TARPIN, Dr
- Email: Tarpin.Paul@chu-amiens.fr
- Phone: 0322087980
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.