Investigating genetic and environmental factors in cardiovascular and renal diseases
Official title: HÉRITABILITÉ FAMILIALE, INTERACTIONS GÈNE-GÈNE ET GÈNE-ENVIRONNEMENT DANS LE DOMAINE DES MALADIES CARDIOVASCULAIRES ET RENALES. Cinquième Visite de la Cohorte STANISLAS
Run by Central Hospital, Nancy, France · NCT05916287 · Data updated 2026-11-12
This study looks at how genes and the environment affect heart and kidney health over time in families to help us understand what can lead to diseases.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 3000 (estimated) |
| Sponsor | Central Hospital, Nancy, France Academic / other |
| Locations | 1 site (Vandœuvre-lès-Nancy, Lorraine) |
| Status | Recruiting |
| Started | July 13, 2023 |
| Main results expected | July 13, 2027 |
| Study ends | July 13, 2027 |
| Registry record updated | August 15, 2023 |
| Trial ID | NCT05916287 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals over 18 who have previously participated in the STANISLAS Cohort and are affiliated with a social security scheme.
✕Probably not a fit
Patients who are currently pregnant, undergoing psychiatric treatment, or unable to provide informed consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The STANISLAS Cohort is a long-term study involving families to explore how genetic and environmental factors contribute to cardiovascular aging and the onset of related diseases. This fifth visit will assess various health parameters, including cardiovascular and renal function, using data collected over decades. Participants will undergo comprehensive evaluations, including blood and urine samples, dietary assessments, and cardiovascular assessments to identify risk factors and potential biomarkers. The study aims to deepen our understanding of how these factors interact and influence health outcomes.
Why it matters
Potential benefit: If successful, this study could lead to improved prevention and treatment strategies for cardiovascular and renal diseases based on genetic and environmental insights.
How similar studies have gone: Previous studies have shown success in understanding gene-environment interactions in cardiovascular diseases, making this approach both relevant and promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * aged over 18 * Person who participated in the Stanislas Cohort * Person affiliated to a social security scheme or beneficiary of such a scheme * Person having received complete information on the organization of the research and having signed an informed consent Exclusion Criteria: * Persons deprived of their liberty by a judicial or administrative decision, persons undergoing psychiatric treatment under Articles L. 3212-1 and L. 3213-1 * Person referred to in Articles L. 1121-5, L. 1121-7 and L1121-8 of the Public Health Code: * Pregnant woman, parturient or nursing mother * Adult person subject to a legal protection measure (guardianship, curatorship, safeguard of justice) * Person of full age unable to express consent
Where it's running
-
CHRU de Nancy
Vandœuvre-lès-Nancy, Lorraine, France Recruiting
Study contacts
- Principal investigator: Nicolas Girerd, MD, PhD — Centre d'Investigation Clinique 1433 module Plurithématique - CHRU Nancy
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.