Clinical trial Recruiting at 1 site Interventional

Investigating genetic and environmental factors in cardiovascular and renal diseases

Official title: HÉRITABILITÉ FAMILIALE, INTERACTIONS GÈNE-GÈNE ET GÈNE-ENVIRONNEMENT DANS LE DOMAINE DES MALADIES CARDIOVASCULAIRES ET RENALES. Cinquième Visite de la Cohorte STANISLAS

Run by Central Hospital, Nancy, France · NCT05916287 · Data updated 2026-11-12

This study looks at how genes and the environment affect heart and kidney health over time in families to help us understand what can lead to diseases.

More Cardiovascular Diseases trials

Quick facts

Study typeInterventional
SexAll
Enrollment3000 (estimated)
SponsorCentral Hospital, Nancy, France
Academic / other
Locations1 site (Vandœuvre-lès-Nancy, Lorraine)
StatusRecruiting
StartedJuly 13, 2023
Main results expectedJuly 13, 2027
Study endsJuly 13, 2027
Registry record updatedAugust 15, 2023
Trial IDNCT05916287 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals over 18 who have previously participated in the STANISLAS Cohort and are affiliated with a social security scheme.

Probably not a fit

Patients who are currently pregnant, undergoing psychiatric treatment, or unable to provide informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The STANISLAS Cohort is a long-term study involving families to explore how genetic and environmental factors contribute to cardiovascular aging and the onset of related diseases. This fifth visit will assess various health parameters, including cardiovascular and renal function, using data collected over decades. Participants will undergo comprehensive evaluations, including blood and urine samples, dietary assessments, and cardiovascular assessments to identify risk factors and potential biomarkers. The study aims to deepen our understanding of how these factors interact and influence health outcomes.

Why it matters

Potential benefit: If successful, this study could lead to improved prevention and treatment strategies for cardiovascular and renal diseases based on genetic and environmental insights.

How similar studies have gone: Previous studies have shown success in understanding gene-environment interactions in cardiovascular diseases, making this approach both relevant and promising.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* aged over 18
* Person who participated in the Stanislas Cohort
* Person affiliated to a social security scheme or beneficiary of such a scheme
* Person having received complete information on the organization of the research and having signed an informed consent

Exclusion Criteria:

* Persons deprived of their liberty by a judicial or administrative decision, persons undergoing psychiatric treatment under Articles L. 3212-1 and L. 3213-1
* Person referred to in Articles L. 1121-5, L. 1121-7 and L1121-8 of the Public Health Code:

  * Pregnant woman, parturient or nursing mother
  * Adult person subject to a legal protection measure (guardianship, curatorship, safeguard of justice)
  * Person of full age unable to express consent

Where it's running

  • CHRU de Nancy
    Vandœuvre-lès-Nancy, Lorraine, France
    Recruiting

Study contacts

  • Principal investigator: Nicolas Girerd, MD, PhD — Centre d'Investigation Clinique 1433 module Plurithématique - CHRU Nancy

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.