Condition

Renal Insufficiency clinical trials and research

• 11Clinical trials
• 13NIH research projects
• 39Countries

Newest Renal Insufficiency clinical trials

All recruiting trials (11)

• Moderate-Intensity Statin + Ezetimibe vs High-Intensity Statin in CKD with ASCVD

  In adults with chronic kidney disease and established cardiovascular disease, this study tests whether a moderate-intensity statin plus ezetimibe can match the benefits of a high-intensity statin alone over three years.

  Recruiting Yonsei University · Seoul · NCT07524101

• Single 3 mg Azvudine safety and blood-level test for adults with mild-to-moderate kidney decline and healthy adults

  This trial gives a single 3 mg dose of Azvudine to adults with mild-to-moderate kidney function decline and to healthy adults to test how the body handles the drug and whether it is safe.

  Recruiting Phase 1 Henan Genuine Biotech Co., Ltd. · Beijing, Beijing Municipality · NCT07001436

• Examining amino acid loss in patients undergoing kidney treatment

  This study looks at how much amino acid is lost in patients receiving kidney treatment in the ICU compared to those who aren't, to help improve nutrition for people with kidney problems.

  Recruiting Medical University of Vienna · Vienna, State of Vienna · NCT06659835

• Assessing quality of life in children with posterior urethral valves

  This study looks at how being treated for posterior urethral valves affects the quality of life for boys aged 6 to 17, focusing on their kidney health and daily living.

  Recruiting Hospices Civils de Lyon · Bron, Bron · NCT06439862

• Combining DV and Toripalimab for Kidney Preservation in Patients with Urothelial Carcinoma

  This study is testing a new combination treatment of DV and toripalimab to see if it can help people with kidney problems and bladder cancer keep their kidneys while treating their cancer.

  Recruiting Phase 2 Fudan University · Shanghai · NCT06354231

• SelfWrap-Assisted Arteriovenous Fistulas for Chronic Kidney Disease

  This study is testing if a new wrap called SelfWrap can make it safer and more effective for people with chronic kidney disease to have a new arteriovenous fistula created.

  Recruiting at 28 sites VenoStent · Bullhead City, Arizona and 27 other locations · NCT06001827

• EvalSel food-frequency questionnaire to measure daily salt intake

  This will test whether the EvalSel food-frequency questionnaire can precisely measure daily salt intake in adults with hypertension, stage 4–5 chronic kidney disease, or without disease.

  Recruiting University Hospital, Lille · Lille · NCT05533645

• Using a new form of Tacrolimus after liver transplantation

  This study is testing a new version of a medication called Envarsus to see if it can help liver transplant patients avoid side effects while still keeping their immune system in check.

  Recruiting Phase 4 University of Alberta · Edmonton, Alberta · NCT05242315

• Comparing two types of membranes to reduce heparin use in dialysis patients

  This study is testing two different types of dialysis membranes to see if they can help reduce the amount of heparin needed during treatment for people with chronic kidney disease.

  Recruiting CHU de Reims · Reims · NCT05117450

• Impact of Stentgraft Treatment on Kidney Function in Aortic Aneurysm Patients

  This study is testing how different ways of fixing stentgrafts can affect kidney function in patients with abdominal aortic aneurysms.

  Recruiting Vastra Gotaland Region · Gothenburg, VastraGotaland · NCT04754659

• Registry for evaluating Medtronic products

  This study is collecting information to see how safe and effective Medtronic products are for patients who are using them.

  Recruiting at 381 sites Medtronic · Birmingham, Alabama and 401 other locations · NCT01524276

NIH-funded research (13)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Chronic Renal Insufficiency Cohort: Phase 5 SDCC Support

  This grant funds a central coordinating center to oversee a long-term study of adults with reduced kidney function and related health outcomes.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11386651

• Chronic Kidney Disease and Aortic Valve Disease: Understanding How Kidney Disease Influences Aortic Stenosis

  This grant looks at how chronic kidney disease may affect the progression of aortic stenosis and whether we can find ways to slow it down for adults with kidney issues.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11374552

• Understanding Kidney Disease and Heart Health

  This long-running project gathers information from people with reduced kidney function to better understand how kidney disease progresses and affects heart health.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11131240

• Johns Hopkins continuation of the Chronic Kidney Disease (CRIC) cohort

  This project continues long-term follow-up of adults with chronic kidney disease to collect health information, tests, and samples that help understand kidney and heart complications.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11131114

• Tracking kidney disease and heart health in adults

  This project follows adults with reduced kidney function to learn how kidney disease progresses and how it affects heart health and other health problems.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11131098

• Tulane Chronic Kidney Disease (CKD) Cohort

  Following thousands of adults with reduced kidney function to learn what factors influence kidney decline and heart disease risk.

  NIH research Tulane University of Louisiana · New Orleans, United States · NIH-11131040

• Long-term chronic kidney disease follow-up at Case Western Reserve

  Researchers will continue following adults with chronic kidney disease to track kidney health and heart problems over time.

  NIH research Case Western Reserve University · Cleveland, United States · NIH-11130938

• Understanding Heart Valve Narrowing in People with Kidney Disease

  This project aims to understand why a heart valve condition called aortic stenosis gets worse in people who also have kidney disease.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-11129624

• Long-term tracking of kidney health and heart outcomes at Kaiser/UCSF

  This project follows adults with chronic kidney disease over time to track changes in kidney function and related heart health problems.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11127720

• CRIC follow-up for adults with chronic kidney disease

  This project continues long-term follow-up of adults with reduced kidney function to track kidney and heart health and collect health and biological data.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11127671

• Investigating how Urotensin II affects kidney function in growth-restricted infants.

  This study is looking at how a substance called Urotensin II might affect the kidneys of babies who didn't grow as much as expected before birth, with the hope of finding ways to help these little ones stay healthier.

  NIH research University of Missouri-Columbia · Columbia, United States · NIH-10908605

• Investigating the link between chronic kidney disease and the progression of aortic stenosis.

  This study is looking at how chronic kidney disease affects the worsening of a heart condition called aortic stenosis, and it's for people with kidney issues who want to understand their heart health better and find new ways to manage their condition.

  NIH research Beth Israel Deaconess Medical Center · Boston, United States · NIH-10844441

• Understanding kidney disease in American Indian populations

  This study is looking at how chronic kidney disease affects American Indians, especially those with diabetes, to find out what makes the disease worse, and it hopes to help create better health plans for these communities by gathering information from 500 participants.

  NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-10671712

Related topics

Quick answers

How many Renal Insufficiency clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 39 countries. The most sites are in France (4 trials), China (3 trials), Austria (2 trials), Canada (2 trials), South Korea (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1, Phase 4: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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