Johns Hopkins continuation of the Chronic Kidney Disease (CRIC) cohort
Limited Competition for the Continuation of the Chronic Renal Insufficiency Cohort (CRIC) Hopkins Clinical Center
This project continues long-term follow-up of adults with chronic kidney disease to collect health information, tests, and samples that help understand kidney and heart complications.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11131114 on NIH RePORTER |
What this research studies
If you take part, the team will continue regular follow-up visits and collect biological samples, clinical tests, and questionnaires to track your kidney and cardiovascular health. They will link your health records with external data sources when possible to capture hospital events and long-term outcomes. The researchers will combine lab results, imaging, and other measurements to identify groups who progress differently and to relate earlier tests to later health events. The study will complete final visits for eligible participants and build data and biospecimen resources for future researchers.
Who could benefit from this research
Good fit: Adults with reduced kidney function (chronic kidney disease), especially current or former CRIC participants or people meeting CRIC enrollment criteria, are the ideal candidates.
Not a fit: People without chronic kidney disease or those seeking immediate treatment changes are unlikely to receive direct clinical benefit because this is an observational follow-up rather than a treatment trial.
Why it matters
Potential benefit: If successful, this work could improve predictions of who will worsen from chronic kidney disease and guide future strategies to prevent kidney failure and heart complications.
How similar studies have performed: CRIC is a long-established, landmark cohort of over 5,600 participants that has already produced many findings linking kidney measures to cardiovascular and other outcomes, so this continuation builds on proven success.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Appel, Lawrence John — Johns Hopkins University
- Study coordinator: Appel, Lawrence John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.