CRIC follow-up for adults with chronic kidney disease
Official title: Continuation of the Chronic Renal Insufficiency Cohort (CRIC)
Funded at University of Pennsylvania · NIH-11127671 · Data updated 2026-11-12
This project continues long-term follow-up of adults with reduced kidney function to track kidney and heart health and collect health and biological data.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 28, 2001 |
| Project end | June 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $1,117,743 |
| NIH project number | 5U24DK060990-25 |
| Project ID | NIH-11127671 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults aged 21 and older with reduced kidney function or chronic kidney disease who can attend a CRIC clinic site or complete home-based testing are ideal candidates.
✕Less likely to help
People without chronic kidney disease or those unable to attend visits or provide samples are unlikely to receive direct benefits from participation.
What this research studies
You would join a long-term group of adults with reduced kidney function who have been followed since 2001, contributing clinic visits, home measurements, and blood and urine samples. The team collects detailed health histories, heart and kidney tests, questionnaires, and links medical record data over time. Smaller ancillary projects may add extra tests or remote monitoring at home. Your participation helps researchers understand how kidney disease and related heart problems change across diverse groups.
Why it matters
Potential benefit: If successful, continuing CRIC could help identify factors that slow kidney decline and prevent heart complications for people with chronic kidney disease.
How similar studies have gone: Earlier phases of CRIC have produced influential findings about CKD progression and cardiovascular complications, so this continuation builds on established success.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Dember, Laura M — University of Pennsylvania
- Study coordinator: Dember, Laura M
Related research
Other NIH-funded projects on the same topics.
-
Chronic Renal Insufficiency Cohort: Phase 5 SDCC Support
This grant funds a central coordinating center to oversee a long-term study of adults with reduced kidney function and related health outcomes.
-
Chronic Kidney Disease and Aortic Valve Disease: Understanding How Kidney Disease Influences Aortic Stenosis
This grant looks at how chronic kidney disease may affect the progression of aortic stenosis and whether we can find ways to slow it down for adults with kidney issues.
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Understanding Kidney Disease and Heart Health
This long-running project gathers information from people with reduced kidney function to better understand how kidney disease progresses and affects heart health.
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Johns Hopkins continuation of the Chronic Kidney Disease (CRIC) cohort
This project continues long-term follow-up of adults with chronic kidney disease to collect health information, tests, and samples that help understand kidney and heart complications.
-
Tracking kidney disease and heart health in adults
This project follows adults with reduced kidney function to learn how kidney disease progresses and how it affects heart health and other health problems.
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Tulane Chronic Kidney Disease (CKD) Cohort
Following thousands of adults with reduced kidney function to learn what factors influence kidney decline and heart disease risk.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.