Understanding Kidney Disease and Heart Health

Chronic Renal Insufficiency Cohort (CRIC) Study

NIH-funded research University of Michigan at Ann Arbor · NIH-11131240

This long-running project gathers information from people with reduced kidney function to better understand how kidney disease progresses and affects heart health.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11131240 on NIH RePORTER

What this research studies

Since 2001, this important project has followed over 5,600 people across the U.S. who have reduced kidney function. We collect detailed health information over time to learn more about how kidney disease changes and how it might lead to heart problems. This helps us discover new ways to predict kidney disease progression and identify factors that contribute to heart issues in people with kidney conditions. The goal is to improve our understanding of these conditions to help patients in the future.

Who could benefit from this research

Good fit: Ideal participants for this type of study are adults aged 21 and older who have reduced kidney function.

Not a fit: Patients seeking immediate treatment or direct medical intervention for their condition would not receive that benefit from participating in this observational study.

Why it matters

Potential benefit: If successful, this work could lead to better ways to predict and manage kidney disease progression and prevent heart complications for people living with kidney conditions.

How similar studies have performed: The CRIC Study is described as a landmark prospective cohort study, indicating its established success in gathering valuable data and expanding research.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiovascular Diseases
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.