Understanding Kidney Disease and Heart Health
Official title: Chronic Renal Insufficiency Cohort (CRIC) Study
Funded at University of Michigan at Ann Arbor · NIH-11131240 · Data updated 2026-11-12
This long-running project gathers information from people with reduced kidney function to better understand how kidney disease progresses and affects heart health.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 28, 2001 |
| Project end | June 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $311,604 |
| NIH project number | 5U01DK061028-25 |
| Project ID | NIH-11131240 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal participants for this type of study are adults aged 21 and older who have reduced kidney function.
✕Less likely to help
Patients seeking immediate treatment or direct medical intervention for their condition would not receive that benefit from participating in this observational study.
What this research studies
Since 2001, this important project has followed over 5,600 people across the U.S. who have reduced kidney function. We collect detailed health information over time to learn more about how kidney disease changes and how it might lead to heart problems. This helps us discover new ways to predict kidney disease progression and identify factors that contribute to heart issues in people with kidney conditions. The goal is to improve our understanding of these conditions to help patients in the future.
Why it matters
Potential benefit: If successful, this work could lead to better ways to predict and manage kidney disease progression and prevent heart complications for people living with kidney conditions.
How similar studies have gone: The CRIC Study is described as a landmark prospective cohort study, indicating its established success in gathering valuable data and expanding research.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Rao, Panduranga S — University of Michigan at Ann Arbor
- Study coordinator: Rao, Panduranga S
Related research
Other NIH-funded projects on the same topics.
-
Chronic Renal Insufficiency Cohort: Phase 5 SDCC Support
This grant funds a central coordinating center to oversee a long-term study of adults with reduced kidney function and related health outcomes.
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Chronic Kidney Disease and Aortic Valve Disease: Understanding How Kidney Disease Influences Aortic Stenosis
This grant looks at how chronic kidney disease may affect the progression of aortic stenosis and whether we can find ways to slow it down for adults with kidney issues.
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Johns Hopkins continuation of the Chronic Kidney Disease (CRIC) cohort
This project continues long-term follow-up of adults with chronic kidney disease to collect health information, tests, and samples that help understand kidney and heart complications.
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Tracking kidney disease and heart health in adults
This project follows adults with reduced kidney function to learn how kidney disease progresses and how it affects heart health and other health problems.
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Tulane Chronic Kidney Disease (CKD) Cohort
Following thousands of adults with reduced kidney function to learn what factors influence kidney decline and heart disease risk.
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Long-term chronic kidney disease follow-up at Case Western Reserve
Researchers will continue following adults with chronic kidney disease to track kidney health and heart problems over time.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.