Tracking kidney disease and heart health in adults
Prospective renal insufficiency cohort evaluation: PRICE
This project follows adults with reduced kidney function to learn how kidney disease progresses and how it affects heart health and other health problems.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11131098 on NIH RePORTER |
What this research studies
If you join, researchers will collect medical histories, blood and urine samples, heart tests, and questionnaires over many years to track health changes. The study follows a diverse group of adults with chronic kidney disease across multiple U.S. clinical centers, including the Penn site that enrolled over 700 people. Collected data include biological measurements, physiological tests, and social and patient-reported information to link kidney changes with cardiovascular outcomes. Long-term follow-up and stored samples help the team find markers that predict worsening kidney function and heart complications.
Who could benefit from this research
Good fit: Adults (usually 21 years and older) with reduced kidney function or chronic kidney disease who can attend clinic visits at a participating center.
Not a fit: People without reduced kidney function, or those already on dialysis or with a kidney transplant, may not be eligible or receive direct benefit from this cohort.
Why it matters
Potential benefit: Results could help identify markers and risk factors to slow kidney disease, prevent heart complications, and guide future treatments.
How similar studies have performed: Large cohorts like CRIC have already produced many important findings linking CKD progression to cardiovascular disease, so this continuation builds on proven success.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Cohen, Debbie L — University of Pennsylvania
- Study coordinator: Cohen, Debbie L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.