Assessing quality of life in children with posterior urethral valves

Quality of Life in School Aged-children With Posterior Urethral Valves

Observational Hospices Civils de Lyon · NCT06439862

This study looks at how being treated for posterior urethral valves affects the quality of life for boys aged 6 to 17, focusing on their kidney health and daily living.

Quick facts

Study typeObservational
Enrollment300 (estimated)
Ages6 Years to 17 Years
SexMale
SponsorHospices Civils de Lyon Academic / other
Locations1 site (Bron, Bron)
Trial IDNCT06439862 on ClinicalTrials.gov

What this trial studies

This observational study focuses on the quality of life in school-aged children who have been treated for posterior urethral valves (PUV), a congenital condition that can lead to significant urinary and renal complications. The study aims to evaluate the long-term effects of PUV treatment on renal function and overall well-being, particularly in relation to chronic kidney disease and urinary incontinence. Participants will be male patients aged 6 to 17 years who were treated for PUV in their first year of life at a specific hospital in Lyon. The study will gather data through quality of life questionnaires completed by the patients and their families.

Who should consider this trial

Good fit: Ideal candidates for this study are male children aged 6 to 17 years who were treated for posterior urethral valves during their first year of life.

Not a fit: Patients with severe cognitive or physical disabilities that prevent them from completing the quality of life questionnaire will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into the long-term quality of life and health outcomes for children affected by posterior urethral valves.

How similar studies have performed: While there is limited data on similar studies specifically focusing on quality of life in PUV patients, the approach of assessing long-term outcomes in congenital conditions has shown promise in other contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male patients and their parents/relatives
* Aged 6 to 17 years old
* Treated for PUV in their first year of life between 2006 and 2018
* Managed in the Femme-Mère-Enfant Hospital in Lyon

Exclusion Criteria:

* Children with pre-existing severe cognitive and physical disability (physician's rating) from other condition
* Children enable to complete QoL questionnaire due to mental or communication impairment

Where this trial is running

Bron, Bron

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Quality of LifePosterior Urethral ValveRenal InsufficiencyChronic Renal DiseaseEnd Stage Renal DiseaseBladder DysfunctionUrinary IncontinenceQuality of life
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.