Tulane Chronic Kidney Disease (CKD) Cohort
Official title: Tulane Clinical Center for Chronic Renal Insufficiency Cohort Study
Funded at Tulane University of Louisiana · NIH-11131040 · Data updated 2026-11-12
Following thousands of adults with reduced kidney function to learn what factors influence kidney decline and heart disease risk.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project start | September 28, 2001 |
| Project end | June 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $261,556 |
| NIH project number | 5U01DK060963-25 |
| Project ID | NIH-11131040 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults aged 21 and older with chronic kidney disease or reduced kidney function who can attend follow-up visits or complete home-based testing are ideal candidates.
✕Less likely to help
People without CKD or those seeking an immediate treatment are unlikely to get direct clinical benefit because the project is observational rather than a treatment trial.
What this research studies
This project follows over 5,600 adults with reduced kidney function across several U.S. centers and collects medical records, blood and urine samples, heart and kidney measurements, questionnaires, and home-based monitoring over time. Researchers combine biological, physiological, and social information to see how different factors link to kidney decline, cardiovascular problems, and other health outcomes. The study runs long-term and includes optional ancillary sub-studies that offer extra tests or monitoring for participants. The goal is to build a detailed picture of who is at higher risk and how progression and complications develop.
Why it matters
Potential benefit: If successful, this work could help identify early warning signs and risk factors that guide ways to slow kidney decline and reduce heart disease in people with CKD.
How similar studies have gone: Long-term cohort studies like CRIC have previously produced important risk markers and CRIC itself has already yielded influential findings on CKD progression and cardiovascular complications.
Where this research is happening
-
Tulane University of Louisiana
New Orleans, United States Active
Researchers
- Principal investigator: Hamm, L Lee — Tulane University of Louisiana
- Study coordinator: Hamm, L Lee
Related research
Other NIH-funded projects on the same topics.
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Chronic Renal Insufficiency Cohort: Phase 5 SDCC Support
This grant funds a central coordinating center to oversee a long-term study of adults with reduced kidney function and related health outcomes.
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Chronic Kidney Disease and Aortic Valve Disease: Understanding How Kidney Disease Influences Aortic Stenosis
This grant looks at how chronic kidney disease may affect the progression of aortic stenosis and whether we can find ways to slow it down for adults with kidney issues.
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Understanding Kidney Disease and Heart Health
This long-running project gathers information from people with reduced kidney function to better understand how kidney disease progresses and affects heart health.
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Johns Hopkins continuation of the Chronic Kidney Disease (CRIC) cohort
This project continues long-term follow-up of adults with chronic kidney disease to collect health information, tests, and samples that help understand kidney and heart complications.
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Tracking kidney disease and heart health in adults
This project follows adults with reduced kidney function to learn how kidney disease progresses and how it affects heart health and other health problems.
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Long-term chronic kidney disease follow-up at Case Western Reserve
Researchers will continue following adults with chronic kidney disease to track kidney health and heart problems over time.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.