Long-term tracking of kidney health and heart outcomes at Kaiser/UCSF
Official title: Chronic Renal Insufficiency Cohort (CRIC) Study Clinical Center
Funded at Kaiser Foundation Research Institute · NIH-11127720 · Data updated 2026-11-12
This project follows adults with chronic kidney disease over time to track changes in kidney function and related heart health problems.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kaiser Foundation Research Institute NIH-funded |
| Lab location | 1 site (Oakland, UNITED STATES) |
| Project start | September 30, 2001 |
| Project end | June 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $289,106 |
| NIH project number | 5U01DK060902-25 |
| Project ID | NIH-11127720 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with chronic kidney disease who are willing to provide medical information and biological samples and to take part in long-term follow-up are the ideal candidates.
✕Less likely to help
People without chronic kidney disease or those already on dialysis or with a kidney transplant are unlikely to be eligible or benefit from this cohort.
What this research studies
If you join, the CRIC network follows you over many years with regular check-ins, health record reviews, and collection of blood, urine, and other samples. The project combines visits at participating clinical centers (including Kaiser Permanente Northern California/UCSF) with remote data collection tools so you can stay involved without frequent travel. Researchers use the measurements and stored biospecimens to map kidney function changes and different types of heart-related events across a large group of adults with CKD. Phase 5 will organize the existing data and samples to support new analyses and future participant follow-up.
Why it matters
Potential benefit: If successful, the work could help doctors predict who is most likely to get worse and guide treatments to prevent kidney failure and heart complications.
How similar studies have gone: Large long-term cohort efforts like CRIC have a strong track record of producing useful findings that link CKD progression with cardiovascular risk.
Where this research is happening
-
Kaiser Foundation Research Institute
Oakland, United States Active
Researchers
- Principal investigator: Go, Alan S — Kaiser Foundation Research Institute
- Study coordinator: Go, Alan S
Related research
Other NIH-funded projects on the same topics.
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Chronic Renal Insufficiency Cohort: Phase 5 SDCC Support
This grant funds a central coordinating center to oversee a long-term study of adults with reduced kidney function and related health outcomes.
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Chronic Kidney Disease and Aortic Valve Disease: Understanding How Kidney Disease Influences Aortic Stenosis
This grant looks at how chronic kidney disease may affect the progression of aortic stenosis and whether we can find ways to slow it down for adults with kidney issues.
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Understanding Kidney Disease and Heart Health
This long-running project gathers information from people with reduced kidney function to better understand how kidney disease progresses and affects heart health.
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Johns Hopkins continuation of the Chronic Kidney Disease (CRIC) cohort
This project continues long-term follow-up of adults with chronic kidney disease to collect health information, tests, and samples that help understand kidney and heart complications.
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Tracking kidney disease and heart health in adults
This project follows adults with reduced kidney function to learn how kidney disease progresses and how it affects heart health and other health problems.
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Tulane Chronic Kidney Disease (CKD) Cohort
Following thousands of adults with reduced kidney function to learn what factors influence kidney decline and heart disease risk.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.