Clinical trial Recruiting at 1 site Interventional Ages 18 and up

EvalSel food-frequency questionnaire to measure daily salt intake

Official title: Development and Validation of a Food Frequency Questionnaire to Assess Sodium Intake in Hospitalized Patients or in Medical Consultation

Run by University Hospital, Lille · NCT05533645 · Data updated 2026-11-12

This will test whether the EvalSel food-frequency questionnaire can precisely measure daily salt intake in adults with hypertension, stage 4–5 chronic kidney disease, or without disease.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment99 (estimated)
SponsorUniversity Hospital, Lille
Academic / other
Locations1 site (Lille)
StatusRecruiting
StartedJune 6, 2023
Main results expectedJune 2026
Study endsJune 2026
Registry record updatedDecember 26, 2025
Trial IDNCT05533645 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (≥18) with hypertension or CKD stages 4–5, or adults without disease, seen in nephrology or cardiology consultations (or recruited by the coordinating center), with health insurance and willing to follow the protocol are ideal candidates.

Probably not a fit

Patients with recent vomiting, diarrhea, intense sweating, recent medication changes, use of interfering medications (e.g., certain effervescent drugs or diuretics unless stable), pregnant or breastfeeding women, and legally protected individuals may not benefit or are excluded.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The EvalSel intervention uses a structured food-frequency questionnaire administered to hospitalized patients or those attending nephrology and cardiology consultations to estimate salt intake to the nearest gram. Participants complete the questionnaire at admission or during follow-up to produce a rapid dietary diagnosis and to identify common dietary errors. The protocol excludes patients with recent large salt losses, recent therapeutic changes, or use of drugs that alter natriuresis, and it enrolls adults over 18 with hypertension, CKD stages 4–5, or healthy controls who have health insurance. The tool is intended to help clinicians refer patients to dietitians and to track salt consumption over time to improve care.

Why it matters

Potential benefit: If successful, EvalSel could let clinicians rapidly identify high salt intake so patients can get timely dietitian referral and tailored advice to help lower blood pressure and protect kidney function.

How similar studies have gone: Similar food-frequency questionnaires and brief dietary tools have been used and often correlate moderately with urinary sodium measurements, but gram-level precision is not consistently demonstrated in prior work.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with high blood pressure, CKD stages 4-5 and patients free from any diseases
* Patients over 18 years old
* Patients in nephrology and cardiology consultation or recruited by CIC
* Patients with health insurance
* Patients willing to follow the full study

Exclusion Criteria:

* Loss of salt by vomiting, diarrhea or sweating (intense sport or intense fever 3 days before urine collection) which can cause a decreasing natriuresis
* Modification of the therapeutic management of patients during the study period
* Taking certain drugs like effervescent drugs, Gaviscon and Tolvaptan during the day of urine collection, as well as diuretics (unless they are taken long-term and the diuresis is stable) which can cause an increasing natriuresis
* Pregnant or breastfeeding women
* Patients protected by law

Where it's running

  • Hôpital Huriez - Service Endocrinologie Diabétologie
    Lille, France
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.