Understanding kidney disease in American Indian populations
Official title: American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC)
Funded at University of New Mexico Health Scis Ctr · NIH-10671712 · Data updated 2026-11-12
This study is looking at how chronic kidney disease affects American Indians, especially those with diabetes, to find out what makes the disease worse, and it hopes to help create better health plans for these communities by gathering information from 500 participants.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Mexico Health Scis Ctr NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project start | July 9, 2019 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $614,646 |
| NIH project number | 5R01DK119199-05 |
| Project ID | NIH-10671712 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are American Indian individuals who are at risk for or currently experiencing chronic kidney disease.
✕Less likely to help
Patients who are not of American Indian descent or those without risk factors for chronic kidney disease may not benefit from this research.
What this research studies
This research focuses on the high prevalence of chronic kidney disease (CKD) among American Indians, particularly those with diabetic kidney disease. It aims to identify risk factors contributing to CKD progression, including traditional factors like diabetes and hypertension, as well as environmental pollutants. By forming a consortium of experienced researchers, the study will gather data from 500 American Indian participants to better understand the disease's impact and prevalence in these communities. The findings could lead to improved health strategies tailored for American Indian populations.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for chronic kidney disease in American Indian communities.
How similar studies have gone: While there has been limited research specifically focused on American Indians and CKD, similar studies in other ethnic groups have shown promising results in understanding and addressing chronic diseases.
Where this research is happening
-
University of New Mexico Health Scis Ctr
Albuquerque, United States Active
Researchers
- Principal investigator: Unruh, Mark Lynn — University of New Mexico Health Scis Ctr
- Study coordinator: Unruh, Mark Lynn
Related research
Other NIH-funded projects on the same topics.
-
Chronic Renal Insufficiency Cohort: Phase 5 SDCC Support
This grant funds a central coordinating center to oversee a long-term study of adults with reduced kidney function and related health outcomes.
-
Chronic Kidney Disease and Aortic Valve Disease: Understanding How Kidney Disease Influences Aortic Stenosis
This grant looks at how chronic kidney disease may affect the progression of aortic stenosis and whether we can find ways to slow it down for adults with kidney issues.
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Understanding Kidney Disease and Heart Health
This long-running project gathers information from people with reduced kidney function to better understand how kidney disease progresses and affects heart health.
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Johns Hopkins continuation of the Chronic Kidney Disease (CRIC) cohort
This project continues long-term follow-up of adults with chronic kidney disease to collect health information, tests, and samples that help understand kidney and heart complications.
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Tracking kidney disease and heart health in adults
This project follows adults with reduced kidney function to learn how kidney disease progresses and how it affects heart health and other health problems.
-
Tulane Chronic Kidney Disease (CKD) Cohort
Following thousands of adults with reduced kidney function to learn what factors influence kidney decline and heart disease risk.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.