Investigating the link between chronic kidney disease and the progression of aortic stenosis.
Chronic Renal Insufficiency and Silent Progression of Aortic Stenosis (CRISP-AS)
This study is looking at how chronic kidney disease affects the worsening of a heart condition called aortic stenosis, and it's for people with kidney issues who want to understand their heart health better and find new ways to manage their condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beth Israel Deaconess Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10844441 on NIH RePORTER |
What this research studies
This research focuses on understanding how chronic kidney disease (CKD) affects the progression of aortic stenosis (AS), a serious heart condition. By analyzing data from large cohorts of patients with CKD, the study aims to identify risk factors that contribute to the worsening of AS. Participants will undergo detailed heart imaging and assessments to track changes over time, which could lead to new insights into managing AS in patients with kidney issues. The findings may help develop better treatment strategies for those at risk of severe AS.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older, particularly those with chronic kidney disease and aortic stenosis.
Not a fit: Patients without chronic kidney disease or those who do not have aortic stenosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management and treatment options for patients with aortic stenosis, particularly those with chronic kidney disease.
How similar studies have performed: Previous research has shown promising results in understanding cardiovascular disease progression in patients with chronic kidney disease, suggesting that this approach may yield valuable insights.
Where this research is happening
Boston, United States
- Beth Israel Deaconess Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Strom, Jordan Blair — Beth Israel Deaconess Medical Center
- Study coordinator: Strom, Jordan Blair
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.