Long-term chronic kidney disease follow-up at Case Western Reserve
Official title: Chronic Renal Insufficiency Cohort Limited competition continuation
Funded at Case Western Reserve University · NIH-11130938 · Data updated 2026-11-12
Researchers will continue following adults with chronic kidney disease to track kidney health and heart problems over time.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | September 28, 2001 |
| Project end | June 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $32,002 |
| NIH project number | 5U01DK061021-25 |
| Project ID | NIH-11130938 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (typically 21 years or older) with chronic kidney disease or reduced kidney function who can attend a participating CRIC clinical center would be ideal candidates.
✕Less likely to help
People without chronic kidney disease or those already on long-term dialysis or with a recent kidney transplant are unlikely to be eligible or to gain direct benefit from this cohort follow-up.
What this research studies
If you join, you would be part of a long-term group of adults with reduced kidney function who have regular visits and data collection. You may give blood and urine samples, have health measurements and questionnaires, and share medical events so researchers can see how kidney and heart health change. The project builds on a diverse cohort recruited at multiple clinical centers and includes many focused ancillary studies. The goal is to find early signs and pathways that lead to worsening kidney disease and heart complications.
Why it matters
Potential benefit: Results could help doctors spot who is most likely to get worse and guide ways to slow kidney decline and prevent heart disease.
How similar studies have gone: The CRIC cohort is a landmark, long-running study whose prior findings have already advanced understanding of CKD progression and cardiovascular complications, so this approach is well established.
Where this research is happening
-
Case Western Reserve University
Cleveland, United States Active
Researchers
- Principal investigator: Rahman, Mahboob — Case Western Reserve University
- Study coordinator: Rahman, Mahboob
Related research
Other NIH-funded projects on the same topics.
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Chronic Renal Insufficiency Cohort: Phase 5 SDCC Support
This grant funds a central coordinating center to oversee a long-term study of adults with reduced kidney function and related health outcomes.
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Chronic Kidney Disease and Aortic Valve Disease: Understanding How Kidney Disease Influences Aortic Stenosis
This grant looks at how chronic kidney disease may affect the progression of aortic stenosis and whether we can find ways to slow it down for adults with kidney issues.
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Understanding Kidney Disease and Heart Health
This long-running project gathers information from people with reduced kidney function to better understand how kidney disease progresses and affects heart health.
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Johns Hopkins continuation of the Chronic Kidney Disease (CRIC) cohort
This project continues long-term follow-up of adults with chronic kidney disease to collect health information, tests, and samples that help understand kidney and heart complications.
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Tracking kidney disease and heart health in adults
This project follows adults with reduced kidney function to learn how kidney disease progresses and how it affects heart health and other health problems.
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Tulane Chronic Kidney Disease (CKD) Cohort
Following thousands of adults with reduced kidney function to learn what factors influence kidney decline and heart disease risk.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.