Long-term chronic kidney disease follow-up at Case Western Reserve

Chronic Renal Insufficiency Cohort Limited competition continuation

NIH-funded research Case Western Reserve University · NIH-11130938

Researchers will continue following adults with chronic kidney disease to track kidney health and heart problems over time.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionCase Western Reserve University NIH-funded
Lab location1 site (Cleveland, United States)
Project IDNIH-11130938 on NIH RePORTER

What this research studies

If you join, you would be part of a long-term group of adults with reduced kidney function who have regular visits and data collection. You may give blood and urine samples, have health measurements and questionnaires, and share medical events so researchers can see how kidney and heart health change. The project builds on a diverse cohort recruited at multiple clinical centers and includes many focused ancillary studies. The goal is to find early signs and pathways that lead to worsening kidney disease and heart complications.

Who could benefit from this research

Good fit: Adults (typically 21 years or older) with chronic kidney disease or reduced kidney function who can attend a participating CRIC clinical center would be ideal candidates.

Not a fit: People without chronic kidney disease or those already on long-term dialysis or with a recent kidney transplant are unlikely to be eligible or to gain direct benefit from this cohort follow-up.

Why it matters

Potential benefit: Results could help doctors spot who is most likely to get worse and guide ways to slow kidney decline and prevent heart disease.

How similar studies have performed: The CRIC cohort is a landmark, long-running study whose prior findings have already advanced understanding of CKD progression and cardiovascular complications, so this approach is well established.

Where this research is happening

Cleveland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiac DiseasesCardiac DisordersCardiovascular Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.