Condition

Preterm Birth clinical trials and research

• 48Clinical trials
• 86NIH research projects
• 24Countries

Newest Preterm Birth clinical trials

All recruiting trials (48)

• Predicting Adverse Pregnancy Outcomes in Uganda through Partnerships and Innovation

  This study tests whether everyday health data, ultrasound, and blood samples from first-time pregnant women in Uganda can help predict problems like preeclampsia, fetal growth restriction, and preterm birth.

  Recruiting at 2 sites Makerere University · Kampala and 1 other locations · NCT07844876

• Cervical stiffness test to help predict preterm birth in at-risk pregnant women

  A simple cervical stiffness test using the Pregnolia device is being studied to see if it can better identify women with threatened preterm labor who are likely to give birth soon.

  Recruiting Pregnolia AG · Prague · NCT07840235

• Prenatal education to reduce environmental exposures during pregnancy

  Aimed at pregnant people, this program tests whether a classroom-style education can help reduce exposure to harmful pollutants from seafood and nearby pollution sources.

  Recruiting at 2 sites The University of Texas Medical Branch, Galveston · Galveston, Texas and 1 other locations · NCT07758114

• How doctors and nurses decide about bed rest in pregnancy

  This study tests a plan to stop routinely restricting activity or bed rest during pregnancy to see if providers accept it, find it appropriate, and change how often they recommend it for women at risk of preterm birth.

  Recruiting at 2 sites University of Pennsylvania · Philadelphia, Pennsylvania and 1 other locations · NCT07698483

• How cervical ultrasound settings affect AI prediction of preterm birth

  This study tests whether an AI model for predicting preterm birth performs differently when cervical ultrasound images are taken with different imaging settings.

  Recruiting Copenhagen University Hospital, Rigshospitalet · Copenhagen · NCT07598097

• Routine STI screening during pregnancy to improve birth outcomes

  This study tests whether adding screening and treatment for chlamydia and gonorrhoea to standard antenatal care can reduce preterm birth and other problems for pregnant women in Botswana.

  Recruiting University of California, San Diego · Gaborone · NCT07458802

• Xylitol Gum to Prevent Premature Birth and Protect Baby Health

  This trial tests whether chewing xylitol gum during pregnancy reduces preterm birth and improves birth outcomes for pregnant people and their babies.

  Recruiting Phase 2/3 University of Washington · Lilongwe · NCT07424846

• Early prediction of lung injury in very preterm infants using EIT and lung ultrasound

  This project will test whether bedside Electrical Impedance Tomography (EIT) and lung ultrasound in stable preterm babies on non-invasive breathing support can spot uneven lung ventilation that predicts severe BPD or death by 36 weeks postmenstrual age.

  Recruiting Fondazione IRCCS Policlinico San Matteo di Pavia · Pavia · NCT07265583

• Household, wellbeing, and quality-of-life impacts of very preterm birth and necrotising enterocolitis

  This project will collect information to see if pausing or continuing milk feeds around blood transfusions relates to babies' quality of life and the financial and emotional impact on families of very preterm infants, especially those with NEC.

  Recruiting at 7 sites Imperial College London · Norwich, Norfolk and 6 other locations · NCT07192393

• How higher temperatures affect pregnant women and newborns in rural Sindh

  This cohort will test whether exposure to high environmental temperatures during pregnancy increases the chances of early birth, low birth weight, or other complications for pregnant women in rural Sindh.

  Recruiting at 3 sites Aga Khan University · Matiari, Sindh and 2 other locations · NCT06957769

• E-health support for families of preterm born children

  This study is testing whether an app can help families of premature babies by providing support and information to improve their care after leaving the hospital.

  Recruiting University Hospital Tuebingen · Tübingen, Baden-Wurttemberg · NCT06939192

• Daily versus split-dose aspirin in high-risk pregnancies

  This test compares taking aspirin 162 mg once daily versus 81 mg twice daily to see which dosing better prevents preeclampsia and preterm birth in people with high-risk singleton pregnancies who start aspirin before 16 weeks.

  Recruiting Phase 1/2 Thomas Jefferson University · Philadelphia, Pennsylvania · NCT06826859

• Determining the best time to measure cervical length during fetal anatomy surveys

  This study is testing the best time to measure cervical length during ultrasounds in pregnant people to see if it makes a difference in accuracy, while also comparing two types of ultrasound images.

  Recruiting Henry Ford Health System · Detroit, Michigan · NCT06822647

• Monitoring blood glucose in pregnant women receiving betamethasone for fetal lung development

  This study looks at how the medication betamethasone affects blood sugar levels in pregnant women who don't have diabetes but are at risk of preterm birth.

  Recruiting University of Aarhus · Aarhus, Central Region Denmark · NCT06794307

• Optimizing feeding methods for preterm infants

  This study is testing two different ways of feeding very low-birth-weight preterm infants to see which method helps them tolerate feeding better and have fewer problems.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna, Bolgona · NCT06760832

• Treating asymptomatic urinary infection during pregnancy in low- and middle-income countries

  This trial will test whether giving pregnant people with asymptomatic bacteriuria nitrofurantoin (versus placebo) can reduce preterm birth, small-for-gestational-age babies, or stillbirth.

  Recruiting at 2 sites Phase 3 NICHD Global Network for Women's and Children's Health · Dhaka, Bangladesh and 6 other locations · NCT06723392

• Teaching parents to test breastmilk sodium levels in preterm infants

  This study is testing if teaching parents how to check the sodium levels in their breastmilk can help improve milk production for their preterm babies.

  Recruiting at 2 sites The Hospital for Sick Children · Seattle, Washington and 1 other locations · NCT06563726

• Switching preterm infants from donor human milk to preterm formula

  This study will try switching preterm and very low birth weight infants who are at least 28 days old and currently on donor human milk to a preterm infant formula to see if they gain weight and length faster and build more fat-free mass.

  Recruiting Augusta University · Augusta, Georgia · NCT06514014

• Exercise program for children born prematurely to improve heart health and cognitive function

  This study is testing whether a fun exercise program can help improve heart health and thinking skills in children aged 6 to 12 who were born prematurely.

  Recruiting University of Basel · Basel, Canton of Basel-City · NCT06500910

• Comparing cervical cerclage with progesterone to progesterone alone for preventing preterm birth

  This study tests whether combining a cervical stitch with progesterone can help pregnant women with a short cervix prevent preterm birth better than using progesterone alone.

  Recruiting Mỹ Đức Hospital · Ho Chi Minh City, Ho Chi Minh City · NCT06463652

• Exploring caregiver-infant relationships in the NICU

  This study looks at how the voices of parents and nurses affect the development of preterm infants in the NICU and how parents' mental health may play a role in this relationship.

  Recruiting Istituto per la Ricerca e l'Innovazione Biomedica · Messina · NCT06462638

• Improving management of preterm premature rupture of membranes with antibiotics

  This study is testing if a new combination of antibiotics can help pregnant people with preterm premature rupture of membranes stay pregnant longer and have healthier babies compared to the usual treatment.

  Recruiting at 2 sites Phase 4 Ohio State University · Columbus, Ohio and 1 other locations · NCT06396078

• Selective antibiotics when symptoms develop versus universal antibiotics for preterm neonates

  In preterm babies at risk for sepsis, researchers test whether giving antibiotics only to those who show symptoms is as safe as giving antibiotics to all at-risk babies in the first week of life.

  Recruiting at 9 sites Phase 3 Indian Council of Medical Research · Chandigarh, Chandigarh and 8 other locations · NCT06377397

• Support for low-income mothers of preterm infants

  This study tests if giving financial help to low-income mothers of preterm babies in the NICU can improve their ability to visit and care for their infants, which may lead to better health for both mom and baby.

  Recruiting at 4 sites University of Massachusetts, Worcester · Atlanta, Georgia and 4 other locations · NCT06362798

• Understanding why young adults born preterm struggle with exercise

  This study is trying to find out why young adults born very preterm have a harder time getting fit through exercise compared to those born at term, by looking at their genetic makeup.

  Recruiting Texas Tech University · Lubbock, Texas · NCT06334107

• Comparing breathing support methods for preterm infants

  This study is testing which breathing support method, CPAP or NIPPV, works better for very low birth weight preterm infants by comparing how their diaphragm functions while using each method.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT06295484

• Peking University Weifang Birth Cohort

  This project will follow pregnant women in Weifang and their children to see if pre-pregnancy and prenatal exposures affect maternal and child health up to age 18.

  Recruiting Peking University · Beijing, Beijing Municipality · NCT06234332

• Comparing laparoscopic and vaginal cerclage for preventing preterm birth

  This study is testing whether a laparoscopic or vaginal stitch can better help women with weak cervixes prevent early births.

  Recruiting at 2 sites University of Aarhus · Aarhus N and 1 other locations · NCT06122506

• Skin-to-skin contact for preterm infants at birth

  This study is testing whether immediate skin-to-skin contact after birth can help moderate and late preterm infants develop better and cope with stress.

  Recruiting University of Cologne · Cologne, Northrhine-westfalia · NCT05975203

• Using cerclage to prevent extreme preterm birth in twin pregnancies with a short cervix

  This study is testing if a special stitch called cerclage can help prevent extremely early births in women carrying twins who have a short cervix.

  Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Antwerp and 12 other locations · NCT05968794

• Using synbiotics to reduce the risk of preterm birth

  This study is testing if taking synbiotics can help women at high risk for preterm birth have healthier pregnancies by improving their vaginal microbiome.

  Recruiting at 9 sites Ziekenhuis Oost-Limburg · Edegem, Antwerpen and 8 other locations · NCT05966649

• Music intervention to help pregnant Black women with chronic stress

  Researchers will test whether a live, culturally based music session can reduce the biological impact of chronic stress during pregnancy and improve birth outcomes for Black women.

  Recruiting Columbia University · New York, New York and 1 other locations · NCT05945264

• L-citrulline supplementation during pregnancy to reduce adverse birth outcomes in Kenyan women at risk of malaria.

  This trial will test whether taking a twice-daily L-citrulline supplement during pregnancy helps Kenyan women at risk of malaria have healthier pregnancies and babies.

  Recruiting Liverpool School of Tropical Medicine · Kisumu · NCT05934318

• Using CO2 Insufflation During Laparoscopy to Treat Premature Infants with Severe Intestinal Inflammation

  This study is testing if a combination of two types of surgery can help premature infants with severe intestinal inflammation feel better and recover more effectively than just one type of surgery.

  Recruiting at 2 sites Assistance Publique - Hôpitaux de Paris · Paris and 1 other locations · NCT05882448

• Prolonged vaginal progesterone to help prevent preterm birth after IVF with fresh embryos

  In people undergoing IVF with a fresh embryo, this study tests whether extending vaginal progesterone treatment reduces the risk of preterm birth.

  Recruiting Phase 4 Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou · NCT05787509

• Using sulfasalazine to lower hormone levels and prevent preterm birth in pregnant women

  This study is testing if the medication sulfasalazine can help pregnant women who have had preterm births by lowering certain hormone levels and preventing them from having another preterm birth.

  Recruiting Phase 2 Rutgers, The State University of New Jersey · New Brunswick, New Jersey · NCT05703425

• Evaluation of pathways for preventing preterm birth

  This study is trying to find ways to prevent preterm birth in pregnant women who are at high risk, while also comparing them to women who are not at risk.

  Recruiting University of Kentucky · Lexington, Kentucky · NCT05246579

• Mitochondrial and stress-related traits linked to preterm birth

  This project will test whether mitochondrial DNA and stress-response changes during early pregnancy are linked to the risk of having a preterm birth in pregnant women under 28 weeks.

  Recruiting Columbia University · New York, New York · NCT05229666

• Using a blood warmer to prevent hypothermia in preterm infants during blood transfusions

  This study is testing if using a blood warmer during blood transfusions can help very preterm infants stay warm and avoid hypothermia.

  Recruiting University of South Carolina · Columbia, South Carolina · NCT05170633

• Single dose of corticosteroids for pregnant individuals at risk of preterm delivery

  This study is testing if a single lower dose of a corticosteroid can help pregnant people at risk of preterm delivery have healthier babies compared to the usual double dose.

  Recruiting at 16 sites Phase 4 McMaster University · Calgary, Alberta and 24 other locations · NCT05114096

• A program to reduce pregnancy risks for Latina and African American women

  This study is testing a new program to help pregnant Latina and African American women improve their mental health and lower the risk of preterm birth through group sessions.

  Recruiting Microgen LLC · Webster, Texas · NCT05012072

• Measuring oxygen extraction in newborns with and without infections

  This study is trying to see if measuring oxygen levels in the blood can show differences between newborns with infections and those without, to help understand their breathing problems better.

  Recruiting Medical University of Graz · Graz, Styria · NCT04818762

• Using surfactant in preterm newborns with NRDS or NARDS

  This research will try to see if giving one dose versus two or more doses of surfactant helps preterm infants with NRDS or NARDS.

  Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Chongqing, Chongqing Municipality · NCT04777760

• Increasing milk production in mothers of extremely preterm infants using a supplement

  This study is testing if a supplement called nicotinamide riboside can help mothers of extremely preterm infants produce more breast milk.

  Recruiting Phase 2/3 University of California, Davis · Sacramento, California · NCT04614714

• Examining attachment in children born prematurely

  This study looks at how being born prematurely affects the way young children connect with their parents and develop emotionally as they grow up.

  Recruiting University Hospital, Angers · Angers and 1 other locations · NCT04304846

• Using antibiotics to prolong pregnancy after premature rupture of membranes

  This study is testing if giving antibiotics to women with a premature rupture of membranes can help them keep their pregnancy going longer.

  Recruiting Phase 4 Woman's · Baton Rouge, Louisiana · NCT04047849

• Exploring factors affecting preterm birth and its outcomes in children

  This study is looking at how genetics and the environment affect preterm birth and its impact on the health of children over time.

  Recruiting Guangzhou Women and Children's Medical Center · Guangzhou · NCT03668327

• Biobank for studying pregnancy complications like preeclampsia and preterm birth

  This study collects samples and information from pregnant women to see if it can help identify the causes of complications like preeclampsia and preterm birth.

  Recruiting CHU de Quebec-Universite Laval · Québec · NCT02744365

NIH-funded research (newest 40 of 86)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Screening and treatment of Chlamydia infection in pregnancy to help prevent preterm birth

  This grant studies whether screening pregnant people for Chlamydia trachomatis and treating those who are positive can reduce the risk of preterm birth.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11617691

• Xylitol to Prevent Periodontal Disease and Preterm Birth in Pregnancy and Early Childhood

  A safe, inexpensive chewable gum approach using xylitol is tested to help pregnant people reduce gum disease and lower the chance of preterm birth and related child health problems.

  NIH research University of Washington · Seattle, United States · NIH-11478593

• Screening and treatment for Chlamydia infection to help prevent preterm birth

  A study in pregnant people will test whether screening for Chlamydia trachomatis and treating it during pregnancy can reduce the risk of babies being born too early.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11474446

• IL-9 Signaling and Immune-Driven Preterm Birth

  This NIH grant supports training a physician-scientist to lead a new lab studying how immune signals, especially IL-9, affect preterm birth.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11452359

• Predicting Preterm Birth with Longitudinal Multi-Omics Data

  A new, patient-friendly approach uses time-aware omics data from pregnancy to better predict preterm birth and uncover underlying biology.

  NIH research Washington University · Saint Louis, United States · NIH-11440408

• Skeletal health after preterm birth in adults

  Researchers will study why people born prematurely have weaker bones and fractures, starting in infancy and following into adulthood.

  NIH research Rush University Medical Center · Chicago, United States · NIH-11427030

• Xylitol for Pregnancy Health and Baby Outcomes

  A safe, affordable gum-based treatment using xylitol is being tested to reduce periodontal disease in pregnant people and lower the chance of preterm birth and related child health issues.

  NIH research University of Washington · Seattle, United States · NIH-11416640

• Autism Risk in Babies Born Earliest (Preterm Birth)

  This project looks at whether being born early (before 37 weeks) changes how autism develops in children, especially compared with babies born on time.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11396513

• Volatile Organic Compounds and Preterm Birth in Detroit

  A large study will follow about 1,100 pregnant women in Detroit to see if exposure to common air pollutants is linked to starting birth earlier than expected in this city.

  NIH research Wayne State University · Detroit, United States · NIH-11394824

• Vaginal Microbiome and Social Factors in Preterm Birth among Hawaiʻi Women

  A study in Hawaiʻi women looks at how the vaginal microbiome and social factors relate to the risk of delivering a baby early.

  NIH research University of Hawaii at Manoa · Honolulu, United States · NIH-11392491

• How pollution near Superfund sites may change the placenta and lead to early birth

  This research looks at whether pollution from nearby Superfund sites changes the placenta's genes and microbes in pregnant people and raises the risk of preterm birth.

  NIH research Baylor College of Medicine · Houston, United States · NIH-11388576

• Screening and treatment for Chlamydia to help prevent preterm birth

  This project tests whether screening pregnant people for Chlamydia trachomatis and treating those who test positive can reduce preterm births.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11386493

• 3-D bioprinted feto-maternal tissue model to test pregnancy drugs

  A high-throughput 3D tissue model of the feto-maternal interface is being built to screen drugs for safety and effectiveness in pregnancy.

  NIH research University of Texas Med Br Galveston · Galveston, United States · NIH-11382114

• New drug ideas to prevent infection-related preterm birth

  A focused program at Vanderbilt aims to train an independent researcher to develop and test new drug approaches to prevent preterm labor caused by infection or inflammation.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11380891

• Fully Quantitative Cervical Elastography to Predict Preterm Birth in First-Time Expectant Mothers

  A new ultrasound method measures cervical stiffness in first-time pregnant women to help predict who might have a preterm birth.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11379992

• How HIV affects vaginal viruses and preterm birth risk in pregnant South African women

  This project looks at whether HIV changes the mix of viruses in the vagina and whether those changes are linked to earlier births among pregnant women in South Africa.

  NIH research Seattle Children's Hospital · Seattle, United States · NIH-11379712

• Non-invasive liquid biopsy screening to predict preterm birth and complications

  A new blood-test approach aims to predict and understand preterm birth and its related conditions in pregnant people and fetuses.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11378539

• Polyamine effects on cervicovaginal health and cervical remodeling in preterm birth

  A study at a major university university will explore how vaginal polyamines influence immune balance and barrier health to help understand and prevent preterm birth.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11378476

• Heart growth and function over time after being born preterm

  This project follows people born preterm to understand how their hearts grow and work as they age, with the goal of finding ways to prevent heart problems.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11373565

• IL-10 delivery via tiny vesicles to delay preterm birth

  Aims to deliver anti-inflammatory IL-10 inside tiny particles to the fetus to help delay preterm birth and reduce inflammation.

  NIH research University of Texas Med Br Galveston · Galveston, United States · NIH-11369666

• Dopamine’s role in mind-body signals linked to spontaneous preterm birth

  This project looks at how dopamine-related signals in a mother may help keep pregnancy on track and prevent early birth, by studying brain, immune, and hormonal interactions in both mice and humans.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11346169

• How fatty acids change after newborn brain injury

  Researchers are studying how energy from fats in the brain changes after a baby’s brain injury from being born early and how this affects brain development.

  NIH research Hugo W. Moser Res Inst Kennedy Krieger · Baltimore, United States · NIH-11332033

• How low vitamin D after preterm birth may harm kidney development

  This project explores whether low vitamin D around the time of preterm birth harms developing kidneys and the podocyte cells that protect kidney filtering.

  NIH research University of Virginia · Charlottesville, United States · NIH-11326227

• Personalized care to reduce prenatal stress and prevent preterm birth

  A personalized, multistep program helps pregnant people reduce stress and lower the chance of having a baby who is born too early.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11313825

• How being born early may affect a child's future heart and metabolic health

  Researchers are using blood samples and long-term health information from a mostly Black urban birth cohort to look for protein and metabolic signs that link preterm birth to higher risk of heart and metabolic problems in childhood and beyond.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11312587

• Epigenomic pathways linked to preterm birth

  Researchers will study how epigenetic changes during pregnancy relate to risk of preterm birth in a large U.S. cohort.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11312568

• Targeting FKBP51 to Prevent Stress-Related Preterm Birth

  A new drug approach aims to block a stress-related protein (FKBP51) to help prevent preterm birth in pregnant people.

  NIH research Dare Bioscience, INC. · San Diego, UNITED STATES · NIH-11310088

• Higher low-dose aspirin to prevent repeat preterm birth

  This project looks at whether giving higher daily low-dose aspirin early in pregnancy helps people who previously had a preterm birth avoid another early delivery.

  NIH research George Washington University · Washington, United States · NIH-11309996

• Traffic pollution and early birth risk

  Researchers will use blood, urine, and microbiome data to find biological signs that link prenatal traffic pollution to preterm birth in pregnant people, especially in African American communities.

  NIH research Emory University · Atlanta, United States · NIH-11295463

• Stretch-Activated Signaling in the Human Uterus to Help Prevent Preterm Birth

  A science team is studying how the human uterus relaxes in order to delay or prevent preterm birth, with a focus on making therapies safer and more effective for pregnant people, especially African American communities.

  NIH research University of Nevada Reno · Reno, United States · NIH-11285017

• Immune monitoring during pregnancy to prevent early birth

  This project uses immune checks in pregnant people to predict and help prevent spontaneous preterm (early) birth.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11258512

• How mucus-producing cervical cells protect against infection in pregnancy

  This project looks at mucus-producing cervical cells in pregnancy to find markers that could signal which pregnant women are at higher risk for infection-related preterm birth.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11257722

• Social stress, cellular aging, and early birth risk in Black women

  This project looks at whether life stress and a DNA-based measure of cellular aging are linked to having a baby before 37 weeks among Black pregnant women.

  NIH research University of Central Florida · Orlando, United States · NIH-11238952

• Culturally based live music program to lower stress-linked preterm birth risk in Black pregnant women

  This 10-week culturally based live music program for Black pregnant women aims to lower stress-related molecules that are linked to preterm birth.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11238934

• Vaginal nanomedicine to prevent inflammation-related preterm birth

  A vaginal nanoparticle delivery system is being used to give medicines that may stop inflammation-triggered early labor in pregnant people at risk of preterm birth.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11237058

• Investigating how racial discrimination and vitamin D levels affect preterm birth in Black women

  This study is looking at how experiences of racial discrimination, feelings of depression, and low vitamin D levels might affect the risk of preterm birth in Black women, by examining blood samples to find out how these factors work together during pregnancy.

  NIH research University of Texas Arlington · Arlington, United States · NIH-11228745

• Autism risk after being born early (preterm)

  This project looks at whether being born before 37 weeks changes how often and why autism happens in children born in Sweden and Finland between 1996 and 2020.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11190851

• 3D lab‑grown fetal‑maternal tissue model to find medicines that prevent preterm birth

  This project uses a 3D lab‑grown model of the tissues between mother and baby to test medicines that might lower the chance of preterm birth for pregnant people.

  NIH research University of Texas Med Br Galveston · Galveston, United States · NIH-11184515

• Investigating the role of vaginal microbiome in preterm birth

  This study is looking at how the bacteria in the vagina might affect the risk of early birth, and it involves pregnant women who can help by sharing samples to improve our understanding of this important health issue.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11178856

• How HIV-related vaginal viruses may affect early births in pregnant South African women

  This work looks at whether differences in vaginal viruses in pregnant women with HIV help explain their higher chances of having a preterm birth.

  NIH research Seattle Children's Hospital · Seattle, United States · NIH-11176710

Related topics

Quick answers

How many Preterm Birth clinical trials are recruiting right now?

48, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 24 countries. The most sites are in United States (17 trials), China (4 trials), Denmark (3 trials), Canada (3 trials), Italy (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 4, Phase 3: 2, Phase 2/3: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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