Music intervention to help pregnant Black women with chronic stress
Official title: The Impact of a Culturally-based Live Music Intervention on the Metabolites and Metabolic Pathways Associated With Chronic Stress and the Risk of Pre-term Birth in Black Women
Run by Columbia University · NCT05945264 · Data updated 2026-11-12
Researchers will test whether a live, culturally based music session can reduce the biological impact of chronic stress during pregnancy and improve birth outcomes for Black women.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | Women only |
| Enrollment | 142 (estimated) |
| Sponsor | Columbia University Academic / other |
| Locations | 2 sites (New York, New York and 1 other locations) |
| Status | Recruiting |
| Started | September 29, 2026 |
| Main results expected | October 31, 2027 |
| Study ends | October 31, 2027 |
| Registry record updated | October 19, 2026 |
| Trial ID | NCT05945264 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are pregnant, aged 18–40, in the first trimester, generally healthy without chronic conditions affecting pregnancy.
✕Probably not a fit
Individuals with chronic medical conditions or those not in the first trimester may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial compares a live music intervention to a sham verbal interaction in pregnant women in the first trimester. It uses metabolomics to see if music lowers stress-related metabolic pathways and aims to improve infant outcomes. The study brings together experts in preterm birth, music therapy, and metabolomics to address disparities. Participants are generally healthy adults aged 18–40 with pregnancy in early gestation. Locations include Mount Sinai and Columbia University systems.
Why it matters
Potential benefit: If successful, the approach could reduce stress-related risks and improve birth outcomes for Black women.
How similar studies have gone: Prior work suggests music-based interventions can influence stress and well-being, but this exact metabolomics-driven approach is novel/limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria * Aged 18 to 40 years * Generally healthy pregnant women in the first trimester of pregnancy Exclusion Criteria: * Non-pregnant women * Women with a chronic medical condition that could impact pregnancy health or duration * Women regularly taking any medications other than prenatal vitamins
Where it's running
-
Columbia University Irving Medical Center/NewYork Presbyterian
New York, New York, United States Recruiting -
Louis Armstrong Center for Music and Medicine at Mount Sinai Health System
New York, New York, United States Active not recruiting
Study contacts
- Principal investigator: Jacquelyn Taylor, PhD — Columbia University
- Study coordinator: Jacquelyn Taylor, PhD
- Email: jyt2116@cumc.columbia.edu
- Phone: 347-978-2871
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.