Screening and treatment for Chlamydia infection to help prevent preterm birth
Official title: Screening and treatment for Chlamydia trachomatis infection to prevent preterm birth
Funded at University of California, San Diego · NIH-11474446 · Data updated 2026-11-12
A study in pregnant people will test whether screening for Chlamydia trachomatis and treating it during pregnancy can reduce the risk of babies being born too early.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | August 1, 2025 |
| Project end | July 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $322,700 |
| NIH project number | 3R01HD116989-02S1 |
| Project ID | NIH-11474446 on NIH RePORTER |
Who could benefit from this research
✓Could help
Pregnant individuals, especially in LMIC settings with high CT prevalence, who consent to screening and treatment as part of prenatal care.
✕Less likely to help
Pregnant people without CT infection or those who do not participate in screening may not benefit.
What this research studies
This project focuses on pregnant individuals, especially in settings like Botswana, to see if routine CT screening and timely treatment during pregnancy lowers preterm birth risk. It builds on earlier findings that CT infection is common and screening is feasible, aiming to provide clearer evidence on birth outcomes. The study will use practical screening approaches and treatment with common antibiotics, tracking birth outcomes and potential transmission effects.
Why it matters
Potential benefit: If successful, the approach could reduce preterm births and improve infant health by screening and treating CT during pregnancy.
How similar studies have gone: Prior research suggested possible reductions in CT prevalence and potential birth outcome benefits, but larger trials are needed for definitive birth outcome effects.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Wynn, Adriane Michelle — University of California, San Diego
- Study coordinator: Wynn, Adriane Michelle
Related research
Other NIH-funded projects on the same topics.
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Screening and treatment of Chlamydia infection in pregnancy to help prevent preterm birth
This grant studies whether screening pregnant people for Chlamydia trachomatis and treating those who are positive can reduce the risk of preterm birth.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.