Skin-to-skin contact for preterm infants at birth

Continuous Delivery Room Skin-to-skin-study for Moderate and Late Preterm Infants

NA · University of Cologne · NCT05975203

This study is testing whether immediate skin-to-skin contact after birth can help moderate and late preterm infants develop better and cope with stress.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
SexAll
SponsorUniversity of Cologne (other)
Locations1 site (Cologne, Northrhine-westfalia)
Trial IDNCT05975203 on ClinicalTrials.gov

What this trial studies

This randomized controlled trial investigates the effects of immediate skin-to-skin contact on moderate and late preterm infants born vaginally. Participants will either be separated from their mothers after birth or receive skin-to-skin contact, allowing researchers to compare outcomes related to gene expression in stress signaling pathways and overall infant development. The study aims to establish a link between early skin-to-skin contact and improved long-term psychosocial and neurological outcomes for these infants.

Who should consider this trial

Good fit: Ideal candidates are preterm infants born between 32 and 36 weeks of gestation via vaginal delivery.

Not a fit: Patients with malformations, those requiring resuscitation, or mothers with severe health issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance the developmental outcomes and stress tolerance of preterm infants.

How similar studies have performed: Previous studies have shown positive outcomes with skin-to-skin contact in preterm infants, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* preterm birth between gestational age of 32 0/7 and 36 6/7 weeks
* vaginal delivery
* singleton
* informed consent before birth

Exclusion Criteria:

* malformations or syndromes of the infant
* resuscitation of the infant
* maternal psychological or severe physical illness
* lack of German language skills

Where this trial is running

Cologne, Northrhine-westfalia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Preterm Birth, Mother-Infant Interaction, Infant Development, preterm behavioral epigenetics, skin-to-skin contact

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.