Exploring factors affecting preterm birth and its outcomes in children
Official title: Preterm Birth Cohort Study in Guangzhou
Run by Guangzhou Women and Children's Medical Center · NCT03668327 · Data updated 2026-11-12
This study is looking at how genetics and the environment affect preterm birth and its impact on the health of children over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | Any age to 18 Years |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Guangzhou Women and Children's Medical Center Academic / other |
| Locations | 1 site (Guangzhou) |
| Status | Recruiting |
| Started | February 1, 2012 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2038 |
| Registry record updated | February 26, 2024 |
| Trial ID | NCT03668327 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are infants born before 37 weeks of gestation at the Guangzhou Women and Children's Medical Center.
✕Probably not a fit
Patients who are part of multiple births, stillbirths, or have major congenital abnormalities may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The Preterm Birth Cohort Study in Guangzhou aims to investigate the genetic and environmental influences on preterm birth, as well as the interactions between these factors. This observational study will collect extensive epidemiological and clinical data, along with biological specimens from mothers and their preterm children. Participants will be followed to assess both short-term and long-term health outcomes, including neurodevelopment and immune development. The findings could provide insights into the mechanisms behind preterm birth and its lasting effects on children's health.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and prevention strategies for preterm birth, ultimately enhancing the health outcomes of affected children.
How similar studies have gone: While there have been studies on preterm birth, this cohort approach focusing on both genetic and environmental factors in a specific population is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Born before 37 weeks of gestation 2. Born in Guangzhou Women and Children's Medical Center 3. Intended to remain in Guangzhou for more than 3 years Exclusion Criteria: 1. Multiple birth 2. Stillbirth 3. With major congenital abnormalities
Where it's running
-
Guangzhou Women and Children's Medical Center, China
Guangzhou, China Recruiting
Study contacts
- Principal investigator: Xiu Qiu, MD,PhD — Guangzhou Women and Children's Medical Center, China
- Study coordinator: Xiu Qiu, MD,PhD
- Email: qxiu0161@163.com
- Phone: 0086 20 38367160
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.